23(E)-eupha-8,23–diene-3β,25-diol-7-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 23(E)-eupha-8,23–diene-3β,25-diol-7-one
• 英文别名: (23E)-3β,25-dihydroxylanosta-8,23-diene；(23E)-lanosta-8,23-diene-3β,25-diol；(3S,5R,10S,13R,14R,17R)-17-[(E,2R)-6-hydroxy-6-methylhept-4-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• 化学式: C₃₀H₅₀O₂
• 分子量: 442.726
• InChiKey: YLPXHUMIKSOPEX-IVBAYRGLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  羊毛甾醇 在 氧气 、 亚甲兰 作用下， 以 乙醇 为溶剂， 以25.4 mg的产率得到23(E)-eupha-8,23–diene-3β,25-diol-7-one
  参考文献：
  名称：

  (20R,23E)-Eupha-8,23-diene-3β,25-diol from Tripetalum cymosum

  摘要：

  A new euphane triterpenoid, (20R,23E)-eupha-8,23-diene-3 beta,25-diol, was isolated from the leaves of Tripetalum cymosum and its structure was determined by spectral analysis and chemical correlation with euphol. Caryophyllene oxide, friedelin, euphol and putranjivic acid were also obtained from the leaves whilst the bark afforded euphol, glutin-5-en-3 beta-ol, butyrospermol and dammara-20,24-dien-3 beta-ol. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00565-2

文献信息

• (20R,23E)-Eupha-8,23-diene-3β,25-diol from Tripetalum cymosum
  作者：Yuan-Wah Leong、Leslie J Harrison

  DOI：10.1016/s0031-9422(98)00565-2

  日期：1999.3

  A new euphane triterpenoid, (20R,23E)-eupha-8,23-diene-3 beta,25-diol, was isolated from the leaves of Tripetalum cymosum and its structure was determined by spectral analysis and chemical correlation with euphol. Caryophyllene oxide, friedelin, euphol and putranjivic acid were also obtained from the leaves whilst the bark afforded euphol, glutin-5-en-3 beta-ol, butyrospermol and dammara-20,24-dien-3 beta-ol. (C) 1999 Elsevier Science Ltd. All rights reserved.