亚甲基二磺酸 | 503-40-2

• 物质功能分类: 化学试剂 - 有机试剂 - 磺酸盐/亚磺酸盐
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 中文名称: 亚甲基二磺酸
• 中文别名: 甲基二磺酸；甲二磺酸
• 英文名称: methanedisulfonic acid
• CAS: 503-40-2
• 化学式: CH₄O₆S₂
• mdl: MFCD00041888
• 分子量: 176.171
• InChiKey: OPUAWDUYWRUIIL-UHFFFAOYSA-N

物化性质

• 熔点：
  96-100°
• 沸点：
  263℃ at 101.3kPa
• 密度：
  1.6517 (rough estimate)
• 溶解度：
  可溶于DMSO（少量加热）、甲醇（轻微）
• LogP：
  -1.49 at 25℃ and pH1
• 解离常数：
  -0.17 at 25℃

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  126
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2904100000
• 包装等级：
  III
• 危险类别：
  8
• 危险性防范说明：
  P280,P303+P361+P353,P304+P340,P305+P351+P338,P310
• 危险品运输编号：
  1759
• 危险性描述：
  H290,H314,H335
• 储存条件：
  室温且干燥

SDS

Material Safety Data Sheet

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Section 1. Identification of the substance
Product Name: Methanedisulfonic acid
Synonyms:

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Section 2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

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Section 3. Composition/information on ingredients.
Ingredient name: Methanedisulfonic acid
CAS number: 503-40-2

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Section 4. First aid measures
Skin contact: Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact: Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation: Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion: Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

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Section 5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

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Section 6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution: Wear approved mask/respirator
Hand precaution: Wear suitable gloves/gauntlets
Skin protection: Wear suitable protective clothing
Eye protection: Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

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Section 7. Handling and storage
Handling: This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

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Section 8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

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Section 9. Physical and chemical properties
Appearance: Not specified
Boiling point: No data
No data
Melting point:
Flash point: No data
Density: No data
Molecular formula: CH4O6S2
Molecular weight: 176.2

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Section 10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, sulfur oxides.

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Section 11. Toxicological information
No data.

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Section 12. Ecological information
No data.

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Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

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Section 14. Transportation information
Non-harzardous for air and ground transportation.

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Section 15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

甲基二磺酸是一种重要的精细化工产品。50%的甲基二磺酸水溶液主要用作电镀催化剂，而含量在一定比例以上的固体则主要用于医药和电池电解液领域。

用途广泛，尤其适用于电镀硬铬工艺中作为主添加剂。

反应信息

• 作为反应物：
  描述：

  亚甲基二磺酸 在 四磷十氧化物 、 三氧化硫 作用下， 生成 甲烷二磺酸亚甲酯
  参考文献：
  名称：

  METHOD FOR PRODUCING METHYLENE DISULFONATE COMPOUND

  摘要：

  Provided is a novel production method capable of easily producing a methylene disulfonate compound. The method for producing a methylene disulfonate compound comprises reacting a specific sulfonic acid compound with a formaldehyde compound in the presence of sulfur trioxide.

  公开号：

  US20220251059A1
• 作为产物：
  描述：

  碘仿 在 potassium sulfite 作用下， 生成 亚甲基二磺酸
  参考文献：
  名称：

  Strecker, Justus Liebigs Annalen der Chemie, 1868, vol. 148, p. 92

  摘要：

  DOI：
• 作为试剂：
  描述：

  乙烯酮 、 丙酮 在 亚甲基二磺酸 作用下， 生成 乙酸异丙烯酯
  参考文献：
  名称：

  Production of enol acetates

  摘要：

  公开号：

  US02461016A1

文献信息

• Method for preparing methanedisulfonic acid
  申请人：HUNAN ASTAR BIO-CHEMICAL TECHNOLOGY CO., LTD.

  公开号：US20150353484A1

  公开（公告）日：2015-12-10

  Disclosed is a method for preparing methanedisulfonic acid, comprising an acidification, wherein the acidification comprises that methanedisulfonate reacts with an acidifier to form a mixture containing methanedisulfonic acid. The disclosure has high yield, low cost, and the process are environmental friendly.

  揭示了一种制备甲烷二磺酸的方法，包括酸化步骤，其中酸化包括甲烷二磺酸盐与酸化剂反应形成含有甲烷二磺酸的混合物。该公开具有高产率、低成本，并且该过程环保。
• 一种环状二磺酸亚甲酯的合成方法
  申请人：湖南阿斯达新材料有限公司

  公开号：CN110818673B

  公开（公告）日：2022-08-16

  本发明公开了一种环状二磺酸亚甲酯的合成方法，它是以烷基二磺酸化合物、二卤代烃化合物和有机碱在高压反应釜中进行加热反应，经简易后处理纯化过程即可获得高纯的环状二磺酸亚甲酯。本发明反应条件温和，工艺简单环保，操作便捷，原料来源广泛，无需金属盐，产物纯度高，制备成本低廉。
• 环状二磺酸硅基酯及其制备方法
  申请人：常熟市常吉化工有限公司

  公开号：CN107573371B

  公开（公告）日：2020-06-02

  本发明公开了一种环状二磺酸硅基酯，包括如下结构式：所述制备方法包括如下步骤：将亚甲基二磺酸或通式(Ⅰ)的亚甲基二磺酸盐与通式(Ⅱ)的二烃基二活性官能团硅烷、通式(Ⅲ)的二烃基环硅氧烷或通式(Ⅳ)的二烃基环硅氮烷在溶剂中按一定的摩尔比反应，控制反应的温度和时间，反应结束后，分离去除溶剂和副产物，得到所述环状二磺酸硅基酯。本发明通过特殊的原料选择及合成工艺设计，开创性制备得到具有不同取代基的环状二磺酸硅基酯，能够有效提高锂二次电池的常温、高温循环性能和高温存储性能，降低电池在高温存储过程中的厚度膨胀；其制备方法工艺步骤简单，可实施性强，所得产物纯度高，色谱纯度达到99％以上，具有广阔的市场前景。
• Olefin oligomerization via new and efficient Brönsted acidic ionic liquid catalyst systems
  作者：Guoqin Wang、Heyuan Song、Ruiyun Li、Zhen Li、Jing Chen

  DOI：10.1016/s1872-2067(18)63071-2

  日期：2018.6

  structures and acidities. The influence of different ionic liquids, ionic liquid loading, different co-catalysts, catalyst ratios (mole ratio of ionic liquid to co-catalyst), reaction time, pressure, temperature, solvent, source of reactants, and the recycling of catalyst systems was studied. Among the synthesized ionic liquids, 1-(4-sulfonic acid)butyl-3-hexylimidazolium hydrogen sulfate ([HIMBs]HSO4) exhibited

  摘要 研究了以布朗斯台德酸性离子液体为主催化剂，三辛基甲基氯化铵为助催化剂的新型催化剂体系催化的烯烃低聚反应。合成的布朗斯台德酸性离子液体通过傅里叶变换红外光谱 (FT-IR)、紫外-可见光谱 (UV)、1H 核磁共振 (NMR) 和 13C NMR 进行表征，以分析其结构和酸度。不同离子液体、离子液体负载量、不同助催化剂、催化剂比（离子液体与助催化剂的摩尔比）、反应时间、压力、温度、溶剂、反应物来源和催化剂体系回收率的影响为学习了。在合成的离子液体中，1-(4-磺酸)丁基-3-己基咪唑硫酸氢盐([HIMBs]HSO4)在测试的反应条件下表现出最好的催化活性。在最佳反应条件下，异丁烯的转化率和三聚体的选择性分别为83.21%和35.80%。此外，催化剂体系易于分离和重复使用；根据实验产物的分布提出了一种可行的反应机理。
• Anionic SO₃H-functionalized ionic liquid: An efficient and recyclable catalyst for the Pechmann reaction of phenols with ethyl acetoacetate
  作者：Dayong Song、Jing Chen、Yong-Min Liang

  DOI：10.1080/00397911.2017.1418000

  日期：2018.3.19

  sulfomethylsulfonate ([Hmim][HO3SCH2SO3]) for the synthesis of coumarins by Pechmann reaction. The [Hmim][HO3SCH2SO3] is easier to prepare by one-step neutralization reaction of N-methylimidazole with methanedisulfonic acid and show high catalytic performance for Pechmann reaction. Besides, the catalyst can simply be separated from the reaction mixture and recycled ten times without noticeable loss of activity. GRAPHICAL

  摘要 本文报道了一种用于通过 Pechmann 反应合成香豆素的阴离子 SO3H 功能化离子液体 N-甲基咪唑磺甲基磺酸盐 ([Hmim][HO3SCH2SO3])。[Hmim][HO3SCH2SO3]通过N-甲基咪唑与甲二磺酸的一步中和反应更容易制备，并且对Pechmann反应具有较高的催化性能。此外，催化剂可以简单地从反应混合物中分离并循环使用十次，而没有明显的活性损失。图形概要

表征谱图