十三烷醇水杨酸酯 | 19666-16-1

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物 - 羧酸酯及其衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 十三烷醇水杨酸酯
• 英文名称: tridecyl salicylate
• 英文别名: Tridecylsalicylat；tridecyl 2-hydroxybenzoate
• CAS: 19666-16-1
• 化学式: C₂₀H₃₂O₃
• 分子量: 320.472
• InChiKey: VLMWBWYAHNRUGC-UHFFFAOYSA-N

物化性质

• 沸点：
  411.1±18.0 °C(Predicted)
• 密度：
  0.989±0.06 g/cm3(Predicted)
• LogP：
  8.637 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  23
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2918230000

制备方法与用途

十三烷醇水杨酸酯可以作为有机合成的中间体和医药中间体，主要应用于实验室研发及化工生产过程。

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE
  申请人：MERCK PATENT GMBH

  公开号：US20200038304A1

  公开（公告）日：2020-02-06

  The present invention relates to the use of monosubstiuted urea derivatives of the formula I as self-tanning substance, for increasing melanin synthesis, for improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these urea derivatives.

  本发明涉及使用式I的单取代脲衍生物作为自日晒剂，用于增加黑色素合成，改善黑色素运输和/或改善黑色素在基底层上方的分布，以及包含这些脲衍生物的制剂。
• GLUCURONOLACTONE DERIVATIVES AS SELF-TANNING SUBSTANCES
  申请人：MERCK PATENT GMBH

  公开号：US20150098914A1

  公开（公告）日：2015-04-09

  The invention relates to the use of specific glucuronolactone derivatives as self-tanning substances, as tanning enhancers for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone, for modulation of the colour shade achieved in the case of tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone, as contrast-reduction agents or for colouring keratin-containing fibres, and to preparations or compositions for colouring keratin-containing fibres comprising these specific glucuronolactone derivatives.

  该发明涉及将特定的葡萄糖醛内酯衍生物用作自我晒黑物质，用作增强二羟基丙酮的晒黑效果，或用于包含二羟基丙酮的自我晒黑物质混合物的调节，以调节使用二羟基丙酮或包含二羟基丙酮的混合物或制剂晒黑时所达到的颜色深浅，作为降低对比度的剂或用于给含角蛋白的纤维着色，以及用于含角蛋白纤维着色的制剂或组合物，其中包括这些特定的葡萄糖醛内酯衍生物。
• BARBITURIC ACID DERIVATIVES AS SELF-TANNING SUBSTANCES
  申请人：Merck Patent GmbH

  公开号：US20200038306A1

  公开（公告）日：2020-02-06

  The present invention relates to the use of barbituric acid derivatives of the formula I as self-tanning substance, for increasing melanin synthesis, for improving melanin transport and/or improving the distribution of melanin in superbasal layers, to preparations comprising these barbituric acid derivatives, and to specific barbituric acid derivatives.

  本发明涉及将式I的巴比妥酸衍生物用作自日晒剂，用于增加黑色素合成，改善黑色素运输和/或改善黑色素在表皮层中的分布，以及含有这些巴比妥酸衍生物的制剂，以及特定的巴比妥酸衍生物。
• Crystalline form of a triazine derivative, the procedure for its production and cosmetic formulations thereof
  申请人：3V SIGMA S.p.A

  公开号：EP2774921A1

  公开（公告）日：2014-09-10

  Disclosed is a crystalline form of the compound of formula (I), characterised by an endothermic melting transition between 20 and 30 J/g at temperatures from 125°C to 135°C, determined by differential scanning calorimetry (DSC) and by its X-ray diffraction spectrum.

  揭示了一种化合物的结晶形式，其特征是在125°C至135°C温度范围内，通过差示扫描量热法（DSC）和X射线衍射光谱确定，在20到30 J/g之间具有一个吸热熔化转变。