四氢-5-氧代-2-苯基呋喃-3-羧酸 | 13389-88-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 中文名称: 四氢-5-氧代-2-苯基呋喃-3-羧酸
• 英文名称: 5-oxo-2-phenyl-tetrahydro-furan-3-carboxylic acid
• 英文别名: 5-oxo-2-phenyltetrahydrofuran-3-carboxylic acid；5-Oxo-2-phenyl-tetrahydro-furan-3-carbonsaeure；β-carboxy-γ-phenyl-γ-butyrolactone；tetrahydro-5-oxo-2-phenyl-3-furancarboxylic acid；γ-Phenyl-paraconsaeure；Phenylparaconsaeure；5-oxo-2-phenyloxolane-3-carboxylic acid
• CAS: 13389-88-3
• 化学式: C₁₁H₁₀O₄
• 分子量: 206.198
• InChiKey: LRMTVZBRYDTDCU-UHFFFAOYSA-N

物化性质

• 熔点：
  95-97 °C
• 沸点：
  467.5±45.0 °C(Predicted)
• 密度：
  1.350±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2932190090

反应信息

• 作为反应物：
  描述：

  四氢-5-氧代-2-苯基呋喃-3-羧酸 生成 4-苯基-3-丁烯酸
  参考文献：
  名称：

  Fittig; Jayne, Justus Liebigs Annalen der Chemie, 1883, vol. 216, p. 103

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 萘 作用下， 生成 四氢-5-氧代-2-苯基呋喃-3-羧酸
  参考文献：
  名称：

  Haerdi; Thorpe, Journal of the Chemical Society, 1925, vol. 127, p. 1246

  摘要：

  DOI：

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• Convenient synthesis of α,β-unsaturated γ-butyrolactones and γ-butyrolactams via decarboxylative iodination of paraconic acids and β-carboxyl-γ-butyrolactams using 1,3-diiodo-5,5-dimethylhydantoin
  作者：Supasorn Phae-nok、Chutima Kuhakarn、Manat Pohmakotr、Vichai Reutrakul、Darunee Soorukram

  DOI：10.1039/c5ob01574j

  日期：——

  A convenient synthetic approach to α,β-unsaturated γ-butyrolactones and α,β-unsaturated γ-butyrolactams is developed. The reaction proceeds via decarboxylative iodination of paraconic acids and β-carboxyl-γ-butyrolactams, employing 1,3-diiodo-5,5-dimethylhydantoin (DIH) under irradiation, followed by dehydroiodination of β-iodo-γ-butyrolactones and γ-butyrolactams providing good yields of α,β-unsaturated

  开发了一种简便的合成方法，合成α，β-不饱和γ-丁内酯和α，β-不饱和γ-丁内酰胺。该反应通过在辐射下使用1,3-二碘-5,5-二甲基乙内酰脲（DIH）对对苯二甲酸和β-羧基-γ-丁内酰胺进行脱羧碘化，然后对β-碘-γ-丁内酯和γ-进行加氢碘化来进行。丁内酰胺可提供高产率的α，β-不饱和γ-丁内酯和γ-丁内酰胺，它们是有机合成中合成有用的组成部分。
• 一种酰胺类杀菌剂
  申请人：南京正荣医药化学有限公司

  公开号：CN108440510A

  公开（公告）日：2018-08-24

  一种酰胺类杀菌剂；本发明涉及农化与医药技术领域，本发明所述的酰胺类杀菌剂比起已知的杀菌剂更有活性、使用功效更好、在使用剂量上也是少于已知杀菌剂的用量，并且本发明中的杀菌剂还具有广谱的杀菌活性，可广泛用于农业、园林等领域防治真菌及南方根结线虫等病害。