1,1,2,2-tetrakis(4-carboxyphenyl)ethane tetraethyl ester | 263369-18-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1,1,2,2-tetrakis(4-carboxyphenyl)ethane tetraethyl ester
• 英文别名: Ethyl 4-[1,2,2-tris(4-ethoxycarbonylphenyl)ethyl]benzoate
• CAS: 263369-18-2
• 化学式: C₃₈H₃₈O₈
• 分子量: 622.715
• InChiKey: SAGZZDZYEZSTFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  46
• 可旋转键数：
  17
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  1,1-bis(4-carboxyphenyl)bromomethane diethyl ester 在 五甲基二乙烯三胺 、 铜 、 copper(I) bromide 作用下， 以 甲苯 为溶剂， 反应 0.5h， 以97%的产率得到1,1,2,2-tetrakis(4-carboxyphenyl)ethane tetraethyl ester
  参考文献：
  名称：

  EP1997798

  摘要：

  公开号：

文献信息

• MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1120391A1

  公开（公告）日：2001-08-01

  Novel molecular compounds containing carboxylic acid derivatives represented by general formula (I) or (II) as the constituent compound and exhibiting excellent performances in various technical fields including selective separation of useful substances, chemical stabilization, nonvolatilization, prolongation of release and powderization, wherein X is (CH2)n or p-phenylene; n is 0, 1, 2 or 3; R1 to R8 and R13 to R20 are each hydrogen, C1-C6 alkyl, C2-C4 alkenyl, phenyl optionally substituted with C1-C6 alkyl, halogeno or C1-C6 alkoxy; and R9 to R12 and R21 to R24 are each hydrogen, C1-C6 alkyl, C2-C4 alkenyl, C7-C12 aralkyl or an alkali metal.

  含有通式(I)或(II)代表的羧酸衍生物作为组成化合物的新型分子化合物，在有用物质的选择性分离、化学稳定、不挥发、延长释放和粉末化等各种技术领域表现出优异性能，其中X为(CH2)n或对亚苯基；n 是 0、1、2 或 3；R1 至 R8 和 R13 至 R20 分别是氢、C1-C6 烷基、C2-C4 烯基、任选被 C1-C6 烷基、卤素或 C1-C6 烷氧基取代的苯基；以及 R9 至 R12 和 R21 至 R24 分别是氢、C1-C6 烷基、C2-C4 烯基、C7-C12 芳基或碱金属。
• MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1780224A1

  公开（公告）日：2007-05-02

  The present invention provides a multibranched polymer represented by the following formula (I), and a method for producing the multibranched polymer: wherein A represents an organic group having 3 or more branched chains, Xa represents a linking group containing any atom of Groups 14 to 16 in the Periodic Table, Y represents a functional group having a structure capable of having an active halogen atom, Q represents an arm moiety having a repeating unit derived from a polymerizable unsaturated bond, m1 represents any integer of 1 to the number of branched chains of A, m2 represents the number of branched chains of A, n1 represents an integer of 0 or 1 or more, and Ra represents an organic group which is not associated with the polymerization reaction.

  本发明提供了由下式（I）表示的多支化聚合物，以及生产这种多支化聚合物的方法： 其中 A 代表具有 3 个或 3 个以上支链的有机基团，Xa 代表含有元素周期表中第 14 至 16 族原子的连接基团，Y 代表具有可具有活性卤原子结构的官能团，Q 代表具有由可聚合不饱和键衍生的重复单元的臂分子，m1 代表 1 至 A 的支链数的任意整数，m2 代表 A 的支链数，n1 代表 0 或 1 或以上的整数，Ra 代表与聚合反应无关的有机基团。
• STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1923418A1

  公开（公告）日：2008-05-21

  The present invention provides a novel narrow distribution dendrimer-like star polymer having a controlled molecular structure, and a method capable of easily producing the star polymer. Disclosed is a polymer comprising a core portion and an arm portion, wherein the arm portion includes a first generation composed of a polymer chain and a second generation composed of a polymer chain formed at the outer shell of the first generation, the number of arms of the second generation is larger than the number of arms of the first generation, the first generation composed of the polymer chain is a polymer chain derived from a monomer having a polymerizable double bond, and the ratio of the weight average molecular weight (Mw) to the number average molecular weight (Mn), (Mw/Mn), of the star polymer is within a range from 1.001 to 2.50. A compound containing a functional group capable of reacting with an anion, which serves as a core portion, is reacted with a polymer chain containing two or more functional groups and an anion end which serves as an arm portion.

  本发明提供了一种具有可控分子结构的新型窄分布树枝状星形聚合物，以及一种能够轻松生产该星形聚合物的方法。 本发明公开了一种聚合物，包括芯部和臂部，其中臂部包括由聚合物链组成的第一代和由在第一代外壳上形成的聚合物链组成的第二代，第二代的臂数大于第一代的臂数、由聚合物链组成的第一代是由具有可聚合双键的单体衍生的聚合物链，且星形聚合物的重量平均分子量（Mw）与数量平均分子量（Mn）之比（Mw/Mn）在 1.001 至 2.50。一种含有能与阴离子反应的官能团（作为核心部分）的化合物与含有两个或两个以上官能团和阴离子末端（作为臂部分）的聚合物链反应。
• STAR POLYMER AND METHOD FOR PRODUCING THE SAME
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2039710A1

  公开（公告）日：2009-03-25

  It is to provide a narrowly dispersible star polymer having a controlled molecular structure and a method for easily producing such star polymer. The method comprises step (A) wherein arm (I) is formed by binding the anionic end of a polymer having an anionic end to a core and step (B) wherein arm (II) is extended from the core by a living radical polymerization. Examples of the star polymer is specifically exemplified by star polymers characterized by having a structure represented by formula (I-1) or (I-2) (In formula (I-1) or (I-2), B, C1 and C2 each independently represents a group composed of a polymer; and m1 and m2 each independently represents an integer of 1 or 2, wherein when m1 or m2 is 2, both C1 or both C2 represent the same group or different groups).

  本发明旨在提供一种具有可控分子结构的窄分散星形聚合物，以及一种易于生产这种星形聚合物的方法。该方法包括步骤(A)和步骤(B)，步骤(A)中，臂(I)通过将具有阴离子端的聚合物的阴离子端与芯结合而形成，步骤(B)中，臂(II)通过活自由基聚合从芯延伸出来。星型聚合物的实例具体举例说明，星型聚合物的特征是具有由式（I-1）或（I-2）表示的结构（在式（I-1）或（I-2）中，B、C1 和 C2 各自独立地代表由聚合物组成的基团；m1 和 m2 各自独立地代表 1 或 2 的整数，其中当 m1 或 m2 为 2 时，C1 或 C2 均代表相同的基团或不同的基团）。
• Star polymer and method for producing the same
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2311900A1

  公开（公告）日：2011-04-20

  The present invention provides a novel narrow distribution dendrimer-like star polymer having a controlled molecular structure, and a method capable of easily producing the star polymer. Disclosed is a polymer comprising a core portion and an arm portion, wherein the arm portion includes a first generation composed of a polymer chain and a second generation composed of a polymer chain formed at the outer shell of the first generation, the number of arms of the second generation is larger than the number of arms of the first generation, the first generation composed of the polymer chain is a polymer chain derived from a monomer having a polymerizable double bond, and the ratio of the weight average molecular weight (Mw) to the number average molecular weight (Mn), (Mw/Mn), of the star polymer is within a range from 1.001 to 2.50. A compound containing a functional group capable of reacting with an anion, which serves as a core portion, is reacted with a polymer chain containing two or more functional groups and an anion end which serves as an arm portion.

  本发明提供了一种具有可控分子结构的新型窄分布树枝状星形聚合物，以及一种能够轻松生产该星形聚合物的方法。 本发明公开了一种聚合物，包括芯部和臂部，其中臂部包括由聚合物链组成的第一代和由在第一代外壳上形成的聚合物链组成的第二代，第二代的臂数大于第一代的臂数、由聚合物链组成的第一代是由具有可聚合双键的单体衍生的聚合物链，且星形聚合物的重量平均分子量（Mw）与数量平均分子量（Mn）之比（Mw/Mn）在 1.001 至 2.50。一种含有能与阴离子反应的官能团（作为核心部分）的化合物与含有两个或两个以上官能团和阴离子末端（作为臂部分）的聚合物链反应。