1,5,5-三甲基环己烷-1,3-二醇 | 116235-87-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1,5,5-三甲基环己烷-1,3-二醇
• 英文名称: 1,5,5-Trimethyl-1,3-cyclohexandiol
• 英文别名: 1,5,5-Trimethylcyclohexane-1,3-diol
• CAS: 116235-87-1
• 化学式: C₉H₁₈O₂
• 分子量: 158.241
• InChiKey: IGGOBQNADHBTSJ-UHFFFAOYSA-N

物化性质

• 沸点：
  246.1±8.0 °C(Predicted)
• 密度：
  1.006±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  氧化异佛尔酮 在 丙二酸二乙酯 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以6%的产率得到3-hydroxy-3,5,5-trimethylcyclohexanone
  参考文献：
  名称：

  Electroreductive ring-opening of .alpha.,.beta.-epoxy carbonyl compounds and their homologs through recyclable use of diphenyl diselenide or diphenyl ditelluride as a mediator

  摘要：

  DOI：

  10.1021/jo00292a032

文献信息

• Use of pharmaceutical compositions comprising cyclohexane derivatives in the treatment or prevention of peptic ulcers
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0282643A2

  公开（公告）日：1988-09-21

  A therapeutic and prophylactic agent for peptic ulcers comprising as an effective ingredient a cyclohexane derivative represented by general formula (I): wherein A represents a group shown by formula, >CH₂, X represents ethynylene, vinylene or ethylene, Y represents oxo or a hydroxy group; R¹, R³, R⁴ and R⁵ each represents a hydrogen atom or substituted or un­substituted alkyl; R² represents a hydrogen atom or substituted or unsubstituted alkyl or a group shown by -OR⁸; R⁶ represents a hydrogen atom, oxo or a group shown by -OR⁸; R⁷ represents a hydrogen atom or a group shown by -OR⁸, and R⁸ represents a hydrogen atom or an organic residue, and a pharmaceutically acceptable additive. Such derivatives are also provided for use as a medicament, particularly for the treatment or prevention of peptic ulcers. The use of such derivatives for the manufacture of a medicament having therapeutic and preventative value is also provided.

  一种消化性溃疡的治疗剂和预防剂，其有效成分包括通式(I)代表的环己烷衍生物： 其中 A 代表由式 >CH₂ 所示的基团、 X 代表乙炔基、乙烯基或乙烯基，Y 代表氧代或羟基； R¹、R³、R⁴ 和 R⁵ 各自代表氢原子或取代或未取代的烷基； R² 代表氢原子或取代或未取代的烷基或式 -OR⁸ 所示的基团；R⁶ 代表氢原子、氧代或-OR⁸所示的基团； R⁷ 代表氢原子或-OR⁸所示的基团，以及 R⁸ 代表氢原子或有机残基，以及药学上可接受的添加剂。 此类衍生物还可用作药物，特别是用于治疗或预防消化性溃疡。 还提供了使用此类衍生物制造具有治疗和预防价值的药物的方法。
• Mixture which can be thermally hardened and hardened by actinic radiation and use thereof
  申请人：——

  公开号：US20040053159A1

  公开（公告）日：2004-03-18

  A mixture curable thermally and with actinic radiation, comprising (A) a binder free from carbon-carbon double bonds activatable with actinic radiation, comprising at least one (meth)acrylate copolymer containing on average per molecule at least one isocyanate-reactive functional group and having a glass transition temperature Tg of from −40 to +80° C., (B) at least one blocked and/or unblocked polyisocyanate having at least one soft, flexibilizing segment, which as a constituent of three-dimensional polymeric networks lowers their glass transition temperature Tg, and (C) at least one unsaturated polyfunctional urethane which is free from isocyanate-reactive functional groups and contains on average per molecule more than four carbon-carbon double bonds activatable with actinic radiation and at least one hardening segment, the hardening segment as a constituent of three-dimensional polymer networks increasing their glass transition temperature Tg; processes for preparing it and its use.

  一种可通过热固化和光辐射固化的混合物，包括 (A) 不含碳碳双键的粘结剂，可通过辐射活化，包括至少一种（甲基）丙烯酸 酯共聚物，平均每个分子含有至少一个异氰酸酯反应官能团，玻璃化温度 Tg 为 -40 至 80 摄氏度、 (B) 至少一种封端和/或未封端的多异氰酸酯，该多异氰酸酯至少有一个柔软的柔 化段，作为三维聚合物网络的成分，可降低其玻璃化转变温度 Tg，以及 (C) 至少一种不饱和多官能度聚氨酯，该聚氨酯不含异氰酸酯反应官能团，每 个分子平均含有四个以上可被辐射活化的碳碳双键和至少一个硬化段，该硬化 段作为三维聚合物网络的组成成分可提高其玻璃化转变温度 Tg； 制备工艺及其用途。
• Aqueous dispersions, which can be hardened thermally and by using actinic radiation, method for the production thereof and their use
  申请人：——

  公开号：US20040052966A1

  公开（公告）日：2004-03-18

  Aqueous dispersions curable thermally and with actinic radiation, comprising (I) liquid, and/or highly viscous solid particles dimensionally stable under storage and application conditions, comprising (IA) a binder free of carbon-carbon double bonds activatable with actinic radiation, comprising at least one (meth)acrylate copolymer containing on average per molecule at least one isocyanate-reactive functional group and at least one dispersive functional group, and (IB) at least one blocked polyisocyanate; (II) liquid, highly viscous and/or solid particles dimensionally stable under storage and application conditions, comprising at least one polyurethane (II) containing at least one isocyanate-reactive functional group, at least one functional group having at least one bond activatable with actinic radiation, and at least one dispersive functional group, and (III) at least one unsaturated constituent which is free of isocyanate-reactive functional groups and contains on average per molecule more than one carbon-carbon double bond activatable with actinic radiation; processes for preparing them, and their use.

  可通过热固化和光辐射固化的水性分散体，包括 (I) 在储存和应用条件下尺寸稳定的液体和/或高粘度固体颗粒，包括 (IA) 不含碳碳双键的粘合剂，可通过辐射活化，包括至少一种（甲基）丙烯酸酯共聚物，平均每个分子含有至少一个异氰酸酯反应性官能团和至少一个分散性官能团，以及 (IB) 至少一种封端多异氰酸酯； (II) 在储存和应用条件下尺寸稳定的液态、高粘度和/或固态颗粒，包括至少一种聚氨酯 (II)，其中含有至少一个异氰酸酯反应官能团、至少一个具有至少一个可被放 射线激活的键的官能团和至少一个分散官能团，以及 (III) 至少一种不饱和成分，不含异氰酸酯反应官能团，且平均每分子含有一个以上可被放 射线激活的碳碳双键； 制备工艺及其用途。
• Coating materials which can be cured thermally and by means of acting radiation, use and method for the production thereof
  申请人：——

  公开号：US20040138389A1

  公开（公告）日：2004-07-15

  Coating materials curable thermally and with actinic radiation, comprising (A) at least one binder containing isocyanate-reactive functional groups and (B) a crosslinking component comprising (i) free and/or blocked isocyanate groups, (ii) reactive functional groups containing at least one bond which can be activated with actinic radiation, (iii) flexibilizing segments which as part of three-dimensional networks lower their glass transition temperature Tg, and (iv) hardening segments which as part of three-dimensional networks raise their glass transition temperature Tg; with the proviso that the crosslinking component (B) comprises or consists of at least one constituent which has the features (i) and (ii); processes for their preparation, and their use.

  可通过热固化和光辐射固化的涂层材料，包括 (A) 至少一种含有异氰酸酯反应官能团的粘合剂和 (B) 交联组分，包括 (i) 游离和/或封端异氰酸酯基团、 (ii) 反应性官能团，其中至少含有一个可被光辐射活化的键、 (iii) 柔化段，作为三维网络的一部分，可降低其玻璃化转变温度 Tg，和 (iv) 硬化段，作为三维网络的一部分，可提高其玻璃化转变温度 Tg； 但交联组分（B）至少包括一种具有（i）和（ii）特征的成分； 其制备工艺及其用途。
• THERMISCH UND MIT AKTINISCHER STRAHLUNG HÄRTBARE PUVERSLURRIES, VERFAHREN ZU IHRER HERSTELLUNG UN DIHRE VERWENDUNG
  申请人：BASF Coatings AG

  公开号：EP1373347A1

  公开（公告）日：2004-01-02