椰油酰基谷氨酸TEA盐 | 68187-29-1

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 谷氨酸类衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 椰油酰基谷氨酸TEA盐
• 英文名称: Triethanolamine glutamate
• 英文别名: (2S)-2-aminopentanedioic acid;2-[bis(2-hydroxyethyl)amino]ethanol
• CAS: 68187-29-1；38732-22-8
• 化学式: C11H24N2O7
• 分子量: 296.32
• InChiKey: TUBPSFQENHCYBW-HVDRVSQOSA-N

物化性质

• 密度：
  0.97[at 20℃]
• LogP：
  -1.58 at 25℃

计算性质

• 辛醇/水分配系数(LogP)：
  -2.47
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• [EN] EXTERNAL PREPARATION FOR SKIN<br/>[FR] PREPARATION EXTERNE POUR LA PEAU
  申请人：SHOWA DENKO KK

  公开号：WO2005094777A1

  公开（公告）日：2005-10-13

  The present invention provides an external preparation for skin, which comprises a multi-branched polysaccharide derivative with multi-branched polysaccharide skeleton consisting of saccharides as constituent units, wherein at least one of hydroxyl (OH) groups in the multi-branched polysaccharide skeleton is substituted by OR (wherein R represents a hydrogen atom, a hydrocarbon having 1 to 30 carbon groups or a hydrocarbon having 1 to 30 carbon groups which has hetero atom), which can give moisture and turgor to the skin, and cosmetics containing the external preparation.

  本发明提供了一种用于皮肤的外用制剂，其包括一种多支链多糖衍生物，该多支链多糖骨架由糖组成的多支链多糖骨架组成，其中多支链多糖骨架中的至少一个羟基（OH）被取代为OR（其中R代表氢原子、具有1至30个碳基团的碳氢化合物或具有1至30个碳基团的碳氢化合物，其具有杂原子），可以为皮肤提供水分和弹性，并且含有该外用制剂的化妆品。
• Soap
  申请人：Kisho Co., Ltd.

  公开号：EP1081216A1

  公开（公告）日：2001-03-07

  According to the invention, there is provided a soap which contains charcoal and tea but contains preferably no artificial perfumery component.

  根据本发明，提供了一种含有木炭和茶叶，但最好不含人工香料成分的肥皂。
• NOVEL CYSTINE DERIVATIVES AND INHIBITORS FOR THE ACTIVATION OF INFLAMMATORY FACTORS
  申请人：Ajinomoto Co., Inc.

  公开号：EP1364943A1

  公开（公告）日：2003-11-26

  A novel cystine derivative of a specific structure, such as N,N'-bis(2-hydroxybenzyl)-L-cystine (which may be in any form of free form, salt, solvate and the like) has been found to have an excellent action to suppress the activation of inflammatory factors. By using the derivative as an effective ingredient, an excellent agent for suppressing the activation of inflammatory factors can be provided. Additionally, the cystine derivative is preferably used for a method for suppressing the activation of inflammatory factors (in particular a method for preventing, ameliorating and/or therapeutically treating diseases (disorders), or skin injuries or disorders involved in the activation of inflammatory factors, a method for preventing, delaying, ameliorating and/or therapeutically treating skin change via aging or aesthetically unfavorable skin change as induced or promoted by inflammatory factors, and the like) and for pharmaceutical agents (pharmaceutical products; external skin application agents, eye drops, nutrition agents, transfusion and the like), cosmetics, foods or drinks and the like which are specific use applications to the agent for suppressing the activation of inflammatory factors. The invention also provides the novel cystine derivative with the excellent action to suppress the activation of inflammatory factors, which can be used as the effective ingredient described above, and a method for producing the same, and additionally provides the method for suppressing the activation of inflammatory factors described above, a use of the cystine derivative (active ingredient) described above for the agent for suppressing the activation of inflammatory factors, and the like.

  研究发现，一种具有特定结构的新型胱氨酸衍生物，如 N,N'-双（2-羟基苄基）-L-胱氨酸（可以是游离态、盐、溶液等任何形式），在抑制炎症因子活化方面具有出色的作用。通过使用该衍生物作为有效成分，可以提供一种抑制炎症因子活化的极佳制剂。此外，胱氨酸衍生物优选用于抑制炎症因子活化的方法（特别是预防、改善和/或治疗涉及炎症因子活化的疾病（失调）或皮肤损伤或失调的方法，预防、延缓、改善和/或治疗由炎症因子诱发或促进的皮肤老化或美观上不利的皮肤变化的方法等）和药物制剂（医药产品；外用皮肤涂抹剂、眼药水、营养剂、输血等）、化妆品、食品或饮料等，这些都是抑制炎症因子活化的药剂的特定用途应用。 本发明还提供了具有良好抑制炎症因子活化作用、可用作上述有效成分的新型胱氨酸衍生物及其生产方法，此外还提供了上述抑制炎症因子活化的方法、上述胱氨酸衍生物（有效成分）在抑制炎症因子活化制剂中的用途等。
• WATER ABSORBING AGENT, PROCESS FOR ITS PRODUCTION, AND ABSORBERS AND ABSORBENT ARTICLES MADE BY USING THE AGENT
  申请人：San-Dia Polymers, Ltd.

  公开号：EP1457541A1

  公开（公告）日：2004-09-15

  A water absorbing agent comprising a crosslinked polymer including a water-soluble vinyl monomer (a1) and/or a vinyl monomer (a2) that is formed into the water-soluble vinyl monomer (a1) by hydrolysis, and a crosslinking agent (b) as an essential constituting unit, wherein the following formulae (1) and (2) are satisfied; a process for its production, and absorbers and absorbent articles made by the water absorbing agent.(Y) ≥ -1.14 (X) + 69.5(X) = ((x1)2 + 4 × (x2)2)1/2 wherein (x1) denotes a water-retention amount (g/g) of the water absorbing agent after being soaked in a physiological saline for one hour; (x2) denotes an absorption amount (g/g) of the water absorbing agent after being soaked in a physiological saline under loading of 0.9 psi for one hour; and (Y) denotes a liquid permeation speed (ml/min) of a physiological saline after the water absorbing agent is soaked in a physiological saline under loading of 0.3 psi for one hour. The water-absorbing agent enables easy production of absorbent articles exhibiting high absorption performance in any state, and is suitable for use in disposable diapers, sanitary napkins, and other sanitary goods.

  一种吸水剂，由交联聚合物组成，交联聚合物包括水溶性乙烯基单体（a1）和/或通过水解形成水溶性乙烯基单体（a1）的乙烯基单体（a2），以及作为基本构成单元的交联剂（b），其中交联剂（b）满足下式（1）和（2）；一种吸水剂的生产工艺，以及由该吸水剂制成的吸水剂和吸水物品。 (Y) ≥ -1.14 (X) + 69.5(X) = ((x1)2 + 4 × (x2)2)1/2 其中，(x1) 表示吸水剂在生理盐水中浸泡一小时后的保水量（克/克）；(x2) 表示吸水剂在生理盐水中以 0.吸水剂在生理盐水中浸泡一小时后的液体渗透速度（毫升/分钟）。这种吸水剂可以轻松生产出在任何状态下都具有高吸水性能的吸水物品，适用于一次性尿布、卫生巾和其他卫生用品。
• SHAMPOO OR BODY DETERGENT COMPOSITION
  申请人：Takasago International Corporation

  公开号：EP1639993A1

  公开（公告）日：2006-03-29

  A shampoo or body detergent composition which comprises (A) a refrigerant substance selected from menthol, menthone, camphor, pulegol, isopulegol, cineole, Japanese peppermint oil, peppermint oil, spearmint oil, and eucalyptus oil, (B) a substance giving a cool feeling and comprising an N-substituted p-menthane-3-carboxamide derivative, (C) an anionic surfactant, and (D) a water-soluble polymer and/or polyhydric alcohol. It optionally contains (E) a substance which gives a warm feeling. The composition is satisfactory in the effect of giving a refrigerant feeling and cool feeling during use and in the retention of that effect thereafter.

  一种洗发水或沐浴露组合物，它包括：(A) 一种制冷物质，选自薄荷醇、薄荷酮、樟脑、柚皮酚、异柚皮酚、丁香油、日本薄荷油、薄荷油、留兰香油和桉叶油；(B) 一种给人凉爽感觉的物质，包括一种 N-取代的对薄荷-3-甲酰胺衍生物；(C) 一种阴离子表面活性剂；(D) 一种水溶性聚合物和/或多元醇。它还可选择含有（E）一种能给人温暖感觉的物质。该组合物在使用过程中产生制冷感和凉爽感，并在使用后保持这种效果方面令人满意。