椰油酰基肌氨酸TEA盐 | 68411-96-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 椰油酰基肌氨酸TEA盐
• 中文别名: N-(椰油酰)肌氨酸三乙醇胺盐
• 英文名称: sarcosine triethanolamine salt
• 英文别名: Triethanolamine cocoyl sarcosinate；2-[bis(2-hydroxyethyl)amino]ethanol;2-(methylamino)acetic acid
• CAS: 68411-96-1
• 化学式: C₃H₇NO₂*C₆H₁₅NO₃
• 分子量: 238.284
• InChiKey: BEABHZRODBBUAU-UHFFFAOYSA-N

物化性质

• LogP：
  -1.108 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.44
• 重原子数：
  16
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  113
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  椰油酰基肌氨酸TEA盐 、 在 二叔丁基过氧化物 作用下， 以 甲苯 为溶剂， 反应 12.0h， 以87%的产率得到
  参考文献：
  名称：

  一种含酚羟基氨基酸表面活性剂的合成方法

  摘要：

  本发明公开了一种含酚羟基氨基酸表面活性剂的合成方法。该方法是将苯并呋喃酮化合物与氨基酸和/或氨基酸盐，在二叔丁基过氧化物氧化剂作用下，进行氧化开环‑缩合串联反应，得到含酚羟基氨基酸表面活性剂。该方法合成的含酚羟基氨基酸衍生物具有更好的生物活性，有更好的药用前景，且合成具有成本较低、产率高、操作简便、无污染等优点，满足工业生产要求。

  公开号：

  CN113999129B

文献信息

• SKIN AGENT FOR EXTERNAL USE AND COSMETIC AGENT INCLUDING UBIQUINONE DERIVATIVE OR SALT THEREOF AND METHOD USING THE SAME
  申请人：Aoki Hirobumi

  公开号：US20100074879A1

  公开（公告）日：2010-03-25

  A skin agent for external use and a cosmetic agent are provided, by transdermal administration of which expected actions and effects of ubiquinone derivatives, salts thereof, ubiquinones and ubiquinols are effectively obtained. The skin agent for external use includes a ubiquinone derivative or a salt thereof as an active ingredient. The ubiquinone derivative is represented by the formula (1): wherein R 1 and R 2 are each a hydrogen atom or a phosphoric group, at least one of R 1 and R 2 is a phosphoric group, and n is an integer in the range of 1 to 9.

  提供了一种外用皮肤剂和化妆品剂，通过经皮给药，可以有效地获得辅酶Q衍生物、其盐、辅酶Q和辅酶QH的预期作用和效果。外用皮肤剂包括辅酶Q衍生物或其盐作为活性成分。辅酶Q衍生物由式（1）表示：其中R1和R2分别是氢原子或磷酸基团，R1和R2中至少有一个是磷酸基团，n是1到9范围内的整数。
• Cation-modified galactomannan polysaccharide and cosmetic composition containing the same
  申请人：Takeda Hiromitsu

  公开号：US20060275235A1

  公开（公告）日：2006-12-07

  The present invention provides a cation-modified galactomannan polysaccharide which gives excellent conditioning effects and gives good feeling and flexibility when it is used in a hair treatment composition, and improves feeling of use by conditioning effects and emulsification conditions when it is used in a skin cosmetic composition such as body cleansing agent. Concretely, the present invention provides a cation-modified galactomannan polysaccharide obtained by substituting some of hydroxyl groups contained in an cation-modified galactomannan polysaccharide which is nonionic polysaccharide and constitutes mannose as a main chain and galactose as a side chain and the composition ratio of mannose and galactose is 1:1 and obtained from albumen portion of a seed of fenugreek ( Trigonella foenum - graecum ) which is a leguminus plant, with a specific quaternary nitrogen-containing group, and a cosmetic composition containing the cation-modified cation-modified galactomannan.

  本发明提供了一种阳离子修饰的半乳糖聚糖多糖，当用于头发护理组合物时，能够提供优异的调理效果，并在使用时给人良好的感觉和柔软度；当用于皮肤化妆品组合物，例如身体清洁剂时，能够通过调理效果和乳化条件来提高使用感受。具体而言，本发明提供了一种阳离子修饰的半乳糖聚糖多糖，其通过用具有特定季铵氮含量的阳离子修饰代替非离子聚糖中含有的一些羟基，该聚糖以甘露糖为主链，以半乳糖为侧链，甘露糖和半乳糖的组成比为1:1，该聚糖来源于胡芦巴（Trigonella foenum-graecum）的种子蛋白质部分。同时，本发明还提供了一种含有该阳离子修饰的半乳糖聚糖多糖的化妆品组合物。
• WHITENING DERMATOLOGICAL PREPARATIONS
  申请人：Kamachi Harumi

  公开号：US20090240070A1

  公开（公告）日：2009-09-24

  Disclosed is a dermatological preparation that are safe and are excellent in inhibiting and removing skin pigmentation and in inhibiting skin roughness. A dermatological preparation comprising a tocopherol aminoalkylcarboxylate and/or a salt thereof, the tocopherol aminoalkylcarboxylate being represented by Formula (I): wherein R 1 is a hydrogen atom or a lower alkyl group; R 2 and R 3 are each independently a hydrogen atom or a methyl group; X is a cycloalkylene group of 3 to 6 carbon atoms; and n is 0 or 1.

  本发明涉及一种皮肤科制剂，其安全有效地抑制和去除皮肤色素沉着，并抑制皮肤粗糙度。该皮肤科制剂包括一种生育酚氨基烷基羧酸酯和/或其盐，所述生育酚氨基烷基羧酸酯由式(I)表示：其中，R1是氢原子或低碳基；R2和R3各自独立地是氢原子或甲基基团；X是3至6个碳原子的环烷基团；n为0或1。
• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• AQUEOUS SUSPENSION OF CROSSLINKED SILICONE PARTICLES, AQUEOUS EMULSION OF OIL CONTAINING CROSSLINKED SILICONE PARTICLES, AND COSMETIC INGREDIENTS
  申请人：Dow Corning Toray Silicone Company, Ltd.

  公开号：EP1541633A1

  公开（公告）日：2005-06-15

  Aqueous suspensions of cross-linked silicone particles comprising : (A) cross-linked silicone particles with an average particle size of from 0.1 to 500 µm, (B) N-acyl-, N-hydrocarbon taurines and/or their salts, and (C) water, aqueous emulsions of oil containing cross-linked silicone particles comprising : (A) cross-linked silicone particles with an average particle size of from 0.1 to 500 µm, (D) oil, (B) N-acyl-, N-hydrocarbon taurines and/or their salts, and (C) water, with component (A) contained in droplets of component (D) dispersed in water, and cosmetic raw materials comprising said aqueous suspensions or said aqueous emulsions. The suspensions and emulsions are characterized by superior stability and by low environmental impact and minimal effects on the human body. In addition, they are extremely useful as cosmetic raw materials because of their superior cosmetics functionality such as wetness and smoothness.

  交联有机硅颗粒的水悬浮液，包括：(A)平均粒径为 0.1 至 500 微米的交联有机硅颗粒，(B)N-酰基-、N-烃基牛磺酸和/或其盐，以及(C)水；含有交联有机硅颗粒的油的水乳液，包括：(A)平均粒径为 0.1至500微米的交联有机硅颗粒，(D)油，(B)N-酰基、N-烃基牛磺酸和/或其盐，以及(C)水，其中组分(A)包含在分散于水中的组分(D)的液滴中，以及包含所述水性悬浮液或所述水性乳液的化妆品原料。这些悬浮液和乳液具有优异的稳定性，对环境的影响较小，对人体的影响也最小。此外，它们作为化妆品原料也非常有用，因为它们具有卓越的化妆品功能，如润湿性和柔滑性。