1-溴-双环[2.2.1]庚烷 | 13474-70-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 1-溴-双环[2.2.1]庚烷
• 英文名称: 1-bromonorbornane
• 英文别名: 1-bromo-norbornane；1-Brom-norbornan；bromo norbornane；bromonorbornane；1-Brom-bicyclo<2.2.1>heptan；1-Bromobicyclo[2.2.1]heptane
• CAS: 13474-70-9
• 化学式: C₇H₁₁Br
• 分子量: 175.068
• InChiKey: IBGQMFDJANKDLZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903890090

反应信息

• 作为反应物：
  描述：

  1-溴-双环[2.2.1]庚烷 生成 降莰烷
  参考文献：
  名称：

  Ashby E. C., Sun Xiaojing, Duff J. L., J. Org. Chem., 59 (1994) N 6, S 1270-1278

  摘要：

  DOI：
• 作为产物：
  描述：

  1-氯双环[2.2.1]庚烷 生成 1-溴-双环[2.2.1]庚烷
  参考文献：
  名称：

  Strained Small Ring Compounds: Bridgehead Substituted Bicyclo [2.1.1]hexanes

  摘要：

  DOI：

  10.1021/ja00903a031

文献信息

• 2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as
  申请人：Sterling Winthrop Inc.

  公开号：US05296496A1

  公开（公告）日：1994-03-22

  4-R.sub.1 -R.sub.2 -R.sub.3 -2-Saccharinylmethyl and 4,7-C-4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates of formulas I and IIA respectively herein, useful in the treatment of degenerative diseases, and compositions containing them, methods for using them to treat degenerative diseases, and processes for their preparation by reaction of the corresponding 2-halomethylsaccharins with a phosphate, phosphonate or phosphinic acid of formula III herein in the presence of an acid-acceptor.

  4-R.sub.1 -R.sub.2 -R.sub.3 -2-糖精基甲基和4,7-C-4,5,6,7-四氢-2-糖精基磷酸酯、膦酸酯和膦酸酯，分别在此处的式I和IIA中，用于治疗退行性疾病，以及含有它们的组合物，使用它们治疗退行性疾病的方法，以及通过将相应的2-卤甲基糖精与此处的式III的磷酸酯、膦酸酯或膦酸反应制备它们的过程，其中存在酸受体。
• 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl
  申请人：Sterling Winthrop Inc.

  公开号：US05187173A1

  公开（公告）日：1993-02-16

  4-R.sub.1 -R.sub.2 -R.sub.3 -2-Saccharinylmethyl, 4-R.sub.4 -4-R.sub.5 -6-R.sub.6 -4,5,6,7-tetrahydro-2-saccharinylmethyl and 4,7-C-4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates of formulas I, II and IIA respectively herein, useful in the treatment of degenerative diseases, and compositions containing them, methods for using them to treat degenerative diseases, and processes for their preparation by reaction of the corresponding 2-halomethylsaccharins with a phosphate, phosphonate or phosphinic acid of formula III herein in the presence of an acid-acceptor.

  4-R.sub.1 -R.sub.2 -R.sub.3 -2-糖精基甲基，4-R.sub.4 -4-R.sub.5 -6-R.sub.6 -4,5,6,7-四氢-2-糖精基甲基和4,7-C-4,5,6,7-四氢-2-糖精基甲酸酯、膦酸酯和膦酸酯，分别在此处的公式I、II和IIA中，用于治疗退行性疾病，以及含有它们的组合物，使用它们治疗退行性疾病的方法，以及通过将相应的2-卤甲基糖精与此处的公式III的磷酸酯、膦酸酯或膦酸反应在酸受体存在下制备它们的方法。
• Method for separating substances
  申请人：Hiratsuka Atsunori

  公开号：US20060113189A1

  公开（公告）日：2006-06-01

  An objective of the present invention is to provide electrophoretic separation methods and devices that enable the various features of a substrate surface that comes in contact with an electrophoresis medium to be controlled. The present invention provides methods for electrophoresing substances, which comprises the steps of: (a) adding a substance to be analyzed to an electrophoresis medium retained in a substrate, whose surface that has come in contact with the electrophoresis medium has been coated with a polymer membrane; and (b) adding electrophoretic pressure to the electrophoresis medium. For example, the use of a plasma-polymerized membrane allows the formation of a membrane with homogeneous quality and thickness on the surface of an arbitrary shape. In addition, desired characteristics can be conferred on the surface through selection of monomeric substances. Protein adsorption onto micro-chips can be effectively prevented as well.

  本发明的一个目标是提供电泳分离方法和设备，使接触电泳介质的基板表面的各种特征可以被控制。本发明提供了一种电泳物质的方法，包括以下步骤：(a)将待分析的物质添加到保留在基板中的电泳介质中，该基板的表面与电泳介质接触，已被涂覆聚合物膜；和(b)向电泳介质施加电泳压力。例如，使用等离子体聚合膜可以在任意形状的表面上形成具有均匀质量和厚度的膜。此外，通过选择单体物质，可以赋予表面所需的特性。蛋白质吸附到微芯片上也可以被有效地防止。
• Correlation of Gas-Phase Stability of Bridgehead Carbocations with Rates of Solvolysis and <i>ab Initio</i> Calculations
  作者：José-Luis M. Abboud、Obis Castaño、Ernest W. Della、Marta Herreros、Paul Müller、Rafael Notario、Jean-Claude Rossier

  DOI：10.1021/ja962319i

  日期：1997.3.1

  resonance spectroscopy (FT ICR) based on dissociative proton attachment (DPA) of bromides and alcohols. The stability of the ions correlates with the solvolytic reactivity of bridgehead derivatives over a rate range of 23 log units, and with theoretical calculations for hydride transfer of bridgehead hydrocarbons at the MP2/6-311G** level.

  桥头碳正离子的稳定性已通过基于溴化物和醇的解离质子附着 (DPA) 的傅立叶变换离子回旋共振光谱 (FT ICR) 确定。离子的稳定性与桥头衍生物在 23 log 单位速率范围内的溶剂分解反应性相关，并且与桥头烃在 MP2/6-311G** 水平上的氢化物转移的理论计算相关。
• Hindered polyalicyclic alkyl catalysts and their use in a gas-phase polymerization reactor
  申请人：Apecetche Maria A.

  公开号：US20080242821A1

  公开（公告）日：2008-10-02

  Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition. In one embodiment, the hindered polyalicyclic alkyl catalyst precursor is formed by first combining an acid, a compound having the formula RX, and a metal oxide selected from the group consisting of Group 3 to Group 10 oxide compounds to produce a catalyst precursor; characterized in that R is selected from the group consisting of hindered polyalicyclic alkyls, and substituted derivatives thereof, and X is selected from the group consisting of any suitable leaving group.

  本发明实施例包括一种聚合烯烃的方法，其中包括将烯烃与通过将受阻的多环烷基催化剂前体与颗粒状无机氧化物结合的过程制备的催化剂组合物接触，沉积时间大于2小时形成催化剂组合物。本发明实施例还包括催化剂组合物，其中包括通过将受阻的多环烷基催化剂前体与颗粒状无机氧化物结合的过程制备的受阻的多环烷基催化剂前体，沉积时间大于2小时形成催化剂组合物。在一个实施例中，受阻的多环烷基催化剂前体首先通过将酸、具有RX式的化合物和从第3组至第10组氧化物化合物中选择的金属氧化物组合而形成，以产生催化剂前体；其中R选择自受阻的多环烷基和其取代衍生物组成的组，X选择自任何适当的脱离基组成的组。

表征谱图