1-甲基-1H-苯并咪唑-4,7-二酮 | 7711-63-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-甲基-1H-苯并咪唑-4,7-二酮
• 英文名称: 1-Methyl-benzimidazol-chinon-(4,7)
• 英文别名: 1-Methylbenzimidazole-4,7-dione
• CAS: 7711-63-9
• 化学式: C₈H₆N₂O₂
• 分子量: 162.148
• InChiKey: PFAIYIKEIPOPRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4,7-二甲氧基-(9ci)-1H-苯并咪唑 在 盐酸 、 potassium dichromate 、 氢氧化钾 、 氢溴酸 作用下， 以 氯仿 、 丙酮 为溶剂， 反应 17.5h， 生成 1-甲基-1H-苯并咪唑-4,7-二酮
  参考文献：
  名称：

  Benzimidazole-4,7-diones as Inhibitors of Protozoal ( Toxoplasma gondii ) Purine Nucleoside Phosphorylase

  摘要：

  Ben zimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibitors of both enzymes. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(02)00064-1

文献信息

• SYNTHESIS OF CONJUGATED POLYMERS VIA OXIDATIVE POLYMERIZATION AND RELATED COMPOSITIONS
  申请人：Plextronics, Inc.

  公开号：US20130109813A1

  公开（公告）日：2013-05-02

  An improved polymerization method including a method comprising providing a reaction mixture comprising a first monomer, an organic oxidant, and at least one Lewis acid or Brönsted acid, wherein the first monomer comprises at least one optionally substituted heterocyclic ring, wherein the heterocyclic ring comprises at least one heteroatom; and reacting the reaction mixture to obtain a conjugated polymer. The method can reduce the content of undesirable entities in the polymer such as halogens and metals, which can be useful in organic electronic device applications. Purification methods also are adapted to remove organic and inorganic impurities.
• US8859718B2
  申请人：——

  公开号：US8859718B2

  公开（公告）日：2014-10-14
• Benzimidazole-4,7-diones as Inhibitors of Protozoal ( Toxoplasma gondii ) Purine Nucleoside Phosphorylase
  作者：Frédéric Alvarez、Arnaud Ghérardi、Pascal Nebois、Marie-Elizabeth Sarciron、Anne-Françoise Pétavy、Nadia Walchshofer

  DOI：10.1016/s0960-894x(02)00064-1

  日期：2002.3

  Ben zimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibitors of both enzymes. (C) 2002 Elsevier Science Ltd. All rights reserved.