2,6,10-三甲基十一醛 | 105-88-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,6,10-三甲基十一醛
• 英文名称: α.ε.ι-trimethyl-undecylaldehyde
• 英文别名: α.ε.ι-Trimethyl-undecylaldehyd；2,6,10-Trimethyl-undecan-11-al；2,6,10-Trimethylundecanal；Undecanal, 2,6,10-trimethyl-
• CAS: 105-88-4
• 化学式: C₁₄H₂₈O
• 分子量: 212.376
• InChiKey: MBZCATXQAHUZEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2912190090

反应信息

• 作为反应物：
  描述：

  L-(+)-酒石酸二异丙酯 、 2,6,10-三甲基十一醛 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 以82%的产率得到Di(1-methylethyl)-(4R,5R)-2-<(1RS,5RS)-1,5,9-trimethyldecyl>-1,3-dioxolan-4,5-dicarboxylat
  参考文献：
  名称：

  Eine neue Methode zur立体化学分析fenkettiger萜类化合物Carbonyl-Verbindungen，† ‡

  摘要：

  无环萜烯基羰基化合物立体化学分析的新方法

  DOI：

  10.1002/hlca.19900730432
• 作为产物：
  描述：

  3,7,11-三甲基-1-十二碳烯 在 溶剂黄146 作用下， 生成 2,6,10-三甲基十一醛
  参考文献：
  名称：

  v.Braun; Anton, Chemische Berichte, 1929, vol. 62, p. 1490

  摘要：

  DOI：

文献信息

• Process of manufacturing aldehydes and the products
  申请人：WINTHROP CHEM CO INC

  公开号：US01899340A1

  公开（公告）日：1933-02-28

  Substituted glycidic acid esters, of the formula <;FORM:0372013/IV/1>; where R1 is hydrogen or alkyl, R2 is a cyclic residue when R1 is hydrogen or any organic residue when R1 is alkyl, and X represents a saturated chain, are manufactured by condensing a halogen-acetic acid ester with a cyclic aldehyde or with a ketone in which the carbon atom of the oxo-group is bound to alkyl and to any organic residue or is a member of a saturated ring, by means of an alkali metal, an alkali metal amide or an alkali metal alcoholate, in a medium in which during the condensation process alkali metal halide does not separate on the condensing agent, viz. a liquid hydrocarbon or a liquid halogenated hydrocarbon. The products are converted into substituted acetaldehydes by saponifying with an alkali, acidifying the solution and steam distilling. In examples: (1) benzaldehyde is condensed with chloracetic acid ethyl ester by means of sodium in the presence of xylene yielding phenylglycidic acid ethyl ester, which is converted into phenylacetaldehyde; (2) 4-methoxybenzaldehyde is similarly treated; (3) 4-chlorobenzaldehyde is similarly converted into 4-chlorophenylglycidic acid ethyl ester and 4-chlorophenylacetaldehyde; (4) acetophenone is condensed with chloracetic acid ethyl ester by means of sodium amide in the presence of benzene or xylene, producing b -phenyl-b -methylglycidic acid ethyl ester, which is converted into 1-oxo-2-phenyl-2-methylethane (hydratropa aldehyde); (5) 2-oxo-6 : 10-dimethylundecane (hexahydropseudoionone) and chloracetic acid ethyl ester are condensed by means of sodium in xylene, yielding the corresponding glycidic ester, which is transformed into 1-oxo-2 : 6 : 10-trimethylundecane; (6) decahydro-2-oxonaphthalene (b -decalone) similarly yields the corresponding glycidic acid ester which is converted into decahydro-2-naphthaldehyde; (7) 1 : 1 : 3-trimethyl-2- (23 - oxobutyl)-cyclohexane (tetrahydroionone) is similarly condensed to produce the corresponding glycidic acid ester, which is converted into 1 : 1 : 3-trimethyl-2-(2<;4>; - oxo - 2<;3>; - methobutyl) - cyclohexane. The properties are also given of the substituted glycidic acid esters and substituted acetaldehydes obtained from: 4-methyl- and 4-ethyl-benzaldehyde, 2 : 4-dimethylbenzaldehyde, 4-isopropylbenzaldehyde, 4-(1<;1>;-methopropyl)-benzaldehyde (obtainable by the action of carbon monoxide on 2-phenylbutane in the presence of aluminium chloride), 2 : 4-diisopropylbenzaldehyde, 5 : 6 : 7 : 8-tetrahydro-1-naphthaldehyde (obtainable by the action of carbon monoxide on tetrahydronaphthalene in the presence of aluminium chloride); 2-oxodecane (methyloctylketone), 2-oxoundecane (methylnonylketone), 2-oxo-2-(p-isopropylphenyl)-ethane (p-isopropylacetophenone), 2-oxo-2-(p-methoxyphenyl)-ethane (methyl - p - methoxyphenylketone), 2 - oxo - 4-phenylbutane, 2 - oxo- 4 - (p-isopropylphenyl)-butane, and 1 : 1 : 3-trimethyl-2-(2<;3>;-oxopentyl)-cyclohexane (obtainable by hydrogenating the corresponding a -methylionone). Other starting materials specified are naphthaldehyde and furfural on the one hand and bromacetic acid esters on the other. Specifications 21047/04, [Class 2, Acids and salts, Organic &;c.], and 293,703, [Class 2 (iii), Dyes &;c.], are referred to.

  替代甘油酸酯，化学式为 <;FORM:0372013/IV/1>; 其中 R1 为氢或烷基，R2 在 R1 为氢时为环残基，在 R1 为烷基时为任何有机残基，X 代表饱和链，通过将卤代乙酸酯与环状醛或酮（其中羟基团的碳原子与烷基和任何有机残基结合，或者是饱和环的成员）与碱金属、碱金属酰胺或碱金属醇酸盐在不分离碱金属卤化物的介质中缩合而制造，该介质在缩合过程中不会使碱金属卤化物分离于缩合剂，即液态烃或液态卤代烃。 通过与碱水解、酸化溶液并蒸馏，将产品转化为替代乙醛。 例如：（1）苯甲醛与氯乙酸乙酯在二甲苯存在下通过钠缩合，生成苯基甘油酸乙酯，进而转化为苯乙醛；（2）4-甲氧基苯甲醛类似处理；（3）4-氯苯甲醛类似转化为4-氯苯基甘油酸乙酯和4-氯苯乙醛；（4）苯乙酮与氯乙酸乙酯在苯或二甲苯存在下通过钠酰胺缩合，产生 b -苯基-b -甲基甘油酸乙酯，进而转化为1-氧代-2-苯基-2-甲基乙烷（水合戊醛）；（5）2-氧代-6 : 10-二甲基十一烷（六氢伪离子酮）与氯乙酸乙酯在二甲苯中通过钠缩合，生成相应的甘油酸酯，转化为1-氧代-2 : 6 : 10-三甲基十一烷；（6）去氢-2-氧代萘烷（b -去氢基酮）类似产生相应的甘油酸酯，转化为去氢-2-萘甲醛；（7）1 : 1 : 3-三甲基-2-（23 - 氧代丁基）-环己烷（四氢伊酮）类似缩合以产生相应的甘油酸酯，转化为1 : 1 : 3-三甲基-2-(2<;4>; - 氧代 - 2<;3>; - 甲基丁基) - 环己烷。 还给出了从以下物质获得的替代甘油酸酯和替代乙醛的性质：4-甲基和4-乙基苯甲醛，2 : 4-二甲基苯甲醛，4-异丙基苯甲醛，4-(1<;1>;-甲基丙基)-苯甲醛（通过一氧化碳在氯化铝存在下作用于2-苯基丁烷获得），2 : 4-二异丙基苯甲醛，5 : 6 : 7 : 8-四氢-1-萘甲醛（通过一氧化碳在氯化铝存在下作用于四氢萘烷获得）；2-氧代癸烷（甲基辛酮），2-氧代十一烷（甲基壬酮），2-氧代-2-(对异丙基苯基)-乙烷（对异丙基苯乙酮），2-氧代-2-(对甲氧基苯基)-乙烷（甲基 - 对 - 甲氧基苯基酮），2 - 氧代 - 4-苯基丁烷，2 - 氧代- 4 - (对异丙基苯基)-丁烷，和1 : 1 : 3-三甲基-2-(2<;3>;-氧代戊基)-环己烷（通过氢化相应的 a -甲基伊酮获得）。 另一方面指定的起始材料是萘甲醛和糠醛，另一方面是溴乙酸酯。 参考规范 21047/04，[2类，酸和盐，有机等]，和 293,703，[2类（iii），染料等]。
• Active-releasing cyclic siloxanes
  申请人：Perry J. Robert

  公开号：US20050136021A1

  公开（公告）日：2005-06-23

  Cyclic siloxanes that contain releasable active ingredients are described. The active ingredient can be an alcohol or enolizable carbonyl-containing compound such as a ketone, aldehyde, or ester. The product siloxanes are useful in a variety of personal and household care products where slow or controlled release of active ingredient is desired. A preferred embodiment utilizes substituents that when released as active ingredients are fragrant.

  本文描述了含有可释放活性成分的环状硅氧烷。活性成分可以是醇或可烯化羰基含有化合物，如酮，醛或酯。该产品硅氧烷在需要缓慢或受控释放活性成分的各种个人和家庭护理产品中非常有用。一种首选实施方案利用了当作为活性成分释放时具有香味的取代基。
• Cyclic siloxane compositions for the release of active ingredients
  申请人：Perry J. Robert

  公开号：US20050136022A1

  公开（公告）日：2005-06-23

  Cyclic siloxanes that contain releasable active ingredients are described. The active ingredient can be an alcohol or enolizable carbonyl-containing compound such as a ketone, aldehyde, or ester. The product siloxanes are useful in a variety of personal and household care products where slow or controlled release of active ingredient is desired. A preferred embodiment utilizes substituents that when released as active ingredients are fragrant.

  描述了含有可释放活性成分的环状硅氧烷。活性成分可以是醇或可烯化羰基含有化合物，如酮，醛或酯。产品硅氧烷在需要缓慢或控制释放活性成分的各种个人和家庭护理产品中非常有用。首选实施方式利用当作为活性成分释放时具有芳香性的取代基。
• Antioxidant chroman compounds
  申请人：Hoffman-La Roche Inc.

  公开号：US03947473A1

  公开（公告）日：1976-03-30

  The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.

  (6-羟基-2-色基)乙酸或羧酸衍生物可用作抗氧化剂，本发明提供了一种从对苯二酚和合成中间体制备这些衍生物的方法，以及在制备光学活性α-生育酚时使用这些衍生物作为中间体的用途。
• Hair Relaxer
  申请人：Shibuya Akira

  公开号：US20080131389A1

  公开（公告）日：2008-06-05

  A hair relaxer includes at least one specific mercapto compound such as 2-methoxyethyl 3-mercaptopropionate, 2-mercapto-4-butanolide and 2-mercapto-4-butyrolactam. The hair relaxer can achieve an excellent effect of shaping and relaxing hair over a wide range of pH values from weak acidity to weak alkalinity. In particular, the hair relaxer displays a more superior hair shaping and relaxing performance in a weakly acidic to neutral pH range. Consequently, the hair relaxer can drastically reduce the damage to the hair and skin and can reliably perform straightening, uncurling, curling and other hair processing.

  一种头发放松剂包括至少一种特定的巯基化合物，例如2-甲氧基乙基3-巯基丙酸酯，2-巯基-4-丁醇内酯和2-巯基-4-丁酰内酰胺。该头发放松剂可以在从弱酸性到弱碱性的广泛pH值范围内实现出色的造型和放松头发的效果。特别是，该头发放松剂在弱酸性到中性pH范围内显示出更卓越的头发造型和放松性能。因此，该头发放松剂可以大大减少对头发和皮肤的损伤，并可可靠地进行拉直、卷曲和其他头发加工。