猴头菌多醇C | 156101-09-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 猴头菌多醇C
• 英文名称: erinacine C
• 英文别名: (1R,2R,5R,10R,14R,16R,17S,18R,21S)-13-(hydroxymethyl)-2,5-dimethyl-8-propan-2-yl-15,20,22-trioxapentacyclo[12.8.0.02,10.05,9.016,21]docosa-8,12-diene-17,18-diol
• CAS: 156101-09-6
• 化学式: C₂₅H₃₈O₆
• 分子量: 434.573
• InChiKey: DMPGFSQMXITJPT-ZCKYJUNOSA-N

物化性质

• 沸点：
  599.3±50.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  31
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  88.4
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  猴头菌多醇C 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 1,4-二氧六环 为溶剂， 生成 猴头菌多醇B
  参考文献：
  名称：

  猴头菌属菌丝体中的神经生长因子（NGF）合成的强刺激物Erinacines A，B和C

  摘要：

  通过解析光谱数据以及化学和酶促反应，确定了从培养的猴头菌菌丝体中分离出的新型二萜类化合物-芥子碱A，B和C的结构。这些化合物显示出有效的神经生长因子（NGF）合成刺激作用。

  DOI：

  10.1016/s0040-4039(00)76760-8

文献信息

• COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID
  申请人：CaaMTech, LLC

  公开号：US20190142851A1

  公开（公告）日：2019-05-16

  This disclosure pertains to new compositions and methods comprising a psilocybin derivative. In one embodiment, the compositions disclosed herein are used for a method of regulating a neurotransmitter receptor, e.g., a serotonin receptor. In one embodiment, the compositions disclosed herein comprise purified compounds, e.g., a purified psilocybin derivative, a purified cannabinoid, or purified terpene.
• COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND
  申请人：CAAMTECH, INC.

  公开号：US20210346346A1

  公开（公告）日：2021-11-11

  Disclosed herein are compositions comprising a serotonergic tryptamine compound, combinations thereof, and methods of using them for treating and preventing a variety of human conditions. In one embodiment, disclosed herein are new compositions and methods which comprise a therapeutically effective amount of a first purified psilocybin derivative and a therapeutically effective amount of a second compound. The second compound is selected from the group consisting of a second purified psilocybin derivative, a purified terpene, a serotonergic drug, an adrenergic drug, a dopaminergic drug, a purified erinacine, and a purified hericenone.
• Erinacines A, B and C, strong stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum
  作者：Hirokazu Kawagishi、Atsushi Shimada、Ryoko Shirai、Kenji Okamoto、Fumihiro Ojima、Hideki Sakamoto、Yukio Ishiguro、Shoei Furukawa

  DOI：10.1016/s0040-4039(00)76760-8

  日期：1994.3

  The structures of novel diterpenoids, erinacines A, B, and C, isolated from the cultured mycelia of Hericium erinaceum were determined by interpretation of the spectral data, and chemical and enzymatic reactions. These compounds showed potent stimulating activity of nerve growth factor (NGF)-synthesis.

  通过解析光谱数据以及化学和酶促反应，确定了从培养的猴头菌菌丝体中分离出的新型二萜类化合物-芥子碱A，B和C的结构。这些化合物显示出有效的神经生长因子（NGF）合成刺激作用。