6-O-(diethoxyphosphoryl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose | 126911-48-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-(diethoxyphosphoryl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose
• 英文别名: alpha-d-Galactopyranose, 1,2:3,4-bis-O-(1-methylethylidene)-, diethyl phosphate；diethyl [(1S,2R,6R,8R,9S)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl]methyl phosphate
• CAS: 126911-48-6
• 化学式: C₁₆H₂₉O₉P
• 分子量: 396.375
• InChiKey: UOVZPMMEOIOFDM-MBJXGIAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.9
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  6-O-(diethoxyphosphoryl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 以 水 为溶剂， 反应 4.0h， 生成 6-O-(diethoxyphosphoryl)-α-D-galactopyranose 、 6-O-(diethoxyphosphoryl)-β-D-galactopyranose
  参考文献：
  名称：

  Autocleavage ofO-Isopropylidene ProtectedO-Phosphono- andO- Thionophosphono Esters of Sugars

  摘要：

  Phosphorylation of D-glucose, D-galactose, D-fructose, glycerol and xylitol acetals with diethoxy- or diphenoxy(thiono)phosphoryl chloride gave the corresponding esters. A novel method of partially and fully deprotecting these compounds, which we have called "autocatalytic cleavage", was effected by simply refluxing in water. Antifungal and insecticidal properties of these compounds are presented.

  DOI：

  10.1080/07328300008544073
• 作为产物：
  描述：

  在 双氧水 、 三乙胺 、 乙酰丙酮 作用下， 以 丙酮 为溶剂， 反应 9.0h， 生成 6-O-(diethoxyphosphoryl)-1,2:3,4-di-O-isopropylidene-α-D-galactopyranose
  参考文献：
  名称：

  Dahlhoff, Wilhelm V.; Taba, Kalulu M., Zeitschrift fur Naturforschung, B: Chemical Sciences, 1989, vol. 44, # 10, p. 1260 - 1262

  摘要：

  DOI：

文献信息

• Autocleavage of<i>O</i>-Isopropylidene Protected<i>O</i>-Phosphono- and<i>O</i>- Thionophosphono Esters of Sugars
  作者：Denis Postel、Gino Ronco、Pierre Villa

  DOI：10.1080/07328300008544073

  日期：2000.1

  Phosphorylation of D-glucose, D-galactose, D-fructose, glycerol and xylitol acetals with diethoxy- or diphenoxy(thiono)phosphoryl chloride gave the corresponding esters. A novel method of partially and fully deprotecting these compounds, which we have called "autocatalytic cleavage", was effected by simply refluxing in water. Antifungal and insecticidal properties of these compounds are presented.
• Dahlhoff, Wilhelm V.; Taba, Kalulu M., Zeitschrift fur Naturforschung, B: Chemical Sciences, 1989, vol. 44, # 10, p. 1260 - 1262
  作者：Dahlhoff, Wilhelm V.、Taba, Kalulu M.

  DOI：——

  日期：——