Tri(propan-2-yl)-(3-quinolin-3-ylindol-1-yl)silane | 553635-70-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: Tri(propan-2-yl)-(3-quinolin-3-ylindol-1-yl)silane
• 英文别名: tri(propan-2-yl)-(3-quinolin-3-ylindol-1-yl)silane
• CAS: 553635-70-4
• 化学式: C₂₆H₃₂N₂Si
• 分子量: 400.639
• InChiKey: CDLMPVMDAYUSRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.88
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Tri(propan-2-yl)-(3-quinolin-3-ylindol-1-yl)silane 在 四丁基氟化铵 作用下， 生成 3-(1H-indol-3-yl)quinoline
  参考文献：
  名称：

  Synthesis of (3-Indolyl)heteroaromatics by Suzuki-Miyaura Coupling and Their Inhibitory Activity in Lipid Peroxidation

  摘要：

  A variety of (3-indolyl)heteroaromatic compounds were synthesized by Suzuki-Miyaura coupling of 3-indolylboronic acid and halogenated heteroaromatics. 2-(3-Indolyl)thiophene showed potent inhibitory activity against lipid peroxidation by rat liver microsome.

  DOI：

  10.3987/com-02-s64
• 作为产物：
  描述：

  3-溴-1-(三异丙基甲硅烷基)吲哚 在 四(三苯基膦)钯 、 叔丁基锂 、 sodium carbonate 作用下， 以 四氢呋喃 、 甲醇 、 苯 为溶剂， 生成 Tri(propan-2-yl)-(3-quinolin-3-ylindol-1-yl)silane
  参考文献：
  名称：

  Synthesis of (3-Indolyl)heteroaromatics by Suzuki-Miyaura Coupling and Their Inhibitory Activity in Lipid Peroxidation

  摘要：

  A variety of (3-indolyl)heteroaromatic compounds were synthesized by Suzuki-Miyaura coupling of 3-indolylboronic acid and halogenated heteroaromatics. 2-(3-Indolyl)thiophene showed potent inhibitory activity against lipid peroxidation by rat liver microsome.

  DOI：

  10.3987/com-02-s64

文献信息

• Synthesis of (3-Indolyl)heteroaromatics by Suzuki-Miyaura Coupling and Their Inhibitory Activity in Lipid Peroxidation
  作者：Atsushi Nishida、Naoki Miyashita、Mihoko Fuwa、Masako Nakagawa

  DOI：10.3987/com-02-s64

  日期：——

  A variety of (3-indolyl)heteroaromatic compounds were synthesized by Suzuki-Miyaura coupling of 3-indolylboronic acid and halogenated heteroaromatics. 2-(3-Indolyl)thiophene showed potent inhibitory activity against lipid peroxidation by rat liver microsome.