1-ethyl-4-methylene-1,4-dihydro-quinoline | 115374-75-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-ethyl-4-methylene-1,4-dihydro-quinoline
• 英文别名: 1-Aethyl-4-methylen-1,4-dihydro-chinolin；1-Ethyl-4-methylene-1,4-dihydroquinoline；1-ethyl-4-methylidenequinoline
• CAS: 115374-75-9
• 化学式: C₁₂H₁₃N
• 分子量: 171.242
• InChiKey: VNSNDFRHWOHYAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-ethyl-4-methylene-1,4-dihydro-quinoline 、 1-(2-Hydroxy-5-nitro-phenyl)-2-[1,3,3-trimethyl-1,3-dihydro-indol-(2E)-ylidene]-ethanone 在 三氯氧磷 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 1-(1-ethyl-4-quinolinia)-2-(2-oxido-4-nitrophenyl)-3-(1,3,3-trimethyl-2-indolinylidene)propene
  参考文献：
  名称：

  Carbocyanine dyes with an o-hydroxyaryl substituent in the meso position of the polymethine chain

  摘要：

  DOI：

  10.1007/bf00475576
• 作为产物：
  描述：

  1-乙基-4-甲基喹啉碘 在 sodium hydroxide 作用下， 生成 1-ethyl-4-methylene-1,4-dihydro-quinoline
  参考文献：
  名称：

  Carbocyanine dyes with an o-hydroxyaryl substituent in the meso position of the polymethine chain

  摘要：

  DOI：

  10.1007/bf00475576

文献信息

• Non-resonant two-photon absorbing material, non-resonant two-photon emitting material, and method for inducing absorption or generating emission of non-resonant two photon by using the material.
  申请人：FUJIFILM Corporation

  公开号：EP2503389A2

  公开（公告）日：2012-09-26

  A non-resonant two-photon absorbing material is provided, comprising a methine dye undergoing a non-resonant two-photon absorption, in which the methine dye is a merocyanine dye, and a non-resonant two-photon absorbing material is provided, comprising a non-resonant two-photon absorbing compound undergoing non-resonant two-photon absorption in the intermolecular aggregation state.

  本发明提供了一种非共振双光子吸收材料，该材料包括一种进行非共振双光子吸收的亚甲基染料，其中亚甲基染料为美蓝染料；还提供了一种非共振双光子吸收材料，该材料包括一种在分子间聚集状态下进行非共振双光子吸收的非共振双光子吸收化合物。
• Compounds for use in a photoelectric conversion material, and intermediates for the preparation thereof
  申请人：Fujifilm Corporation

  公开号：EP2786983A1

  公开（公告）日：2014-10-08

  The invention provides a compound represented by the following formula (V): Also claimed are compounds of formula (I) which are useful as a photoelectric conversion material. The aldehydes of formula (V) are intermediates in the preparation of compounds of formula (I).

  本发明提供了由下式（V）代表的化合物： 本发明还涉及可用作光电转换材料的式 (I) 化合物。式（V）的醛是制备式（I）化合物的中间体。
• ANTI-NEURODEGENERATIVE DISEASE AGENT
  申请人：Hayashibara Co., Ltd.

  公开号：EP3858355A1

  公开（公告）日：2021-08-04

  The present invention addresses the problem of providing an orally-administrable anti-neurodegenerative disease agent having an action of accelerating neurocyte growth and an action of promoting neurite-outgrowth, and having excellent transfer properties to central nervous tissues. The problem is solved by providing an anti-neurodegenerative disease agent containing a compound represented by General formula 4 as an active ingredient, and having an action of accelerating neurocyte growth, an action of promoting neurite-outgrowth, and an action of scavenging reactive oxygen species. In General formula 4, R10 and R11 represent the same or different alkyl group having 2-8 carbon atoms, and the alkyl group may be either a straight chain or a branched chain. n represents an integer of 0 or 1, and X4- represents a suitable counter anion that is pharmaceutically acceptable.

  本发明所要解决的问题是提供一种可口服的抗神经退行性疾病药物，该药物具有加速神经细胞生长和促进神经元生长的作用，并且对中枢神经组织具有良好的转移特性。本发明通过提供一种抗神经退行性疾病制剂来解决上述问题，该制剂含有通式 4 所代表的化合物作为活性成分，具有加速神经细胞生长的作用、促进神经元生长的作用以及清除活性氧的作用。通式 4 中，R10 和 R11 代表具有 2-8 个碳原子的相同或不同的烷基，烷基可以是直链或支链，n 代表 0 或 1 的整数，X4- 代表药学上可接受的合适的反阴离子。
• Methine dye sensitized semiconductor particle
  申请人：FUJIFILM Corporation

  公开号：EP0892411B1

  公开（公告）日：2007-09-19
• PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS
  申请人：HAMANO Mitsumasa

  公开号：US20110056562A1

  公开（公告）日：2011-03-10

  A compound represented by the following formula (I), and a photoelectric conversion device containing the compound: wherein Z 1 is a ring containing two carbon atoms and represents a 5-membered ring, a 6-membered ring or a condensed ring containing at least either a 5-membered ring or a 6-membered ring, each of L 1 , L 2 and L 3 independently represents an unsubstituted methine group or a substituted methine group, n represents an integer of 0 or more, each of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 independently represents a hydrogen atom or a substituent, R 1 and R 2 , R 2 and R 3 , R 4 and R 5 , or R 5 and R 6 may be combined with each other to form a ring, and each of R 21 and R 22 independently represents a substituted aryl group, an unsubstituted aryl group, a substituted heteroaryl group or an unsubstituted heteroaryl group, provided that the case where both R 21 and R 22 are an unsubstituted phenyl group is excluded.