2-methyl-5-phytylquinol | 98931-25-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-methyl-5-phytylquinol
• 英文别名: 2-methyl-5-[(E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl]benzene-1,4-diol
• CAS: 98931-25-0
• 化学式: C₂₇H₄₆O₂
• 分子量: 402.661
• InChiKey: UHENQFJOSPDXLZ-UOFXASEASA-N

物化性质

• 沸点：
  521.9±45.0 °C(Predicted)
• 密度：
  0.942±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.6
• 重原子数：
  29
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methyl-5-phytylquinol 在 silver(l) oxide 作用下， 以 乙醚 为溶剂， 生成 2-(丙-2-炔-1-基)己酸
  参考文献：
  名称：

  2-Methyl-6-phytylquinol and 2,3-dimethyl-5-phytylquinol as precursors of tocopherol synthesis in spinach chloroplasts

  摘要：

  The incorporation of [Me(methyl)-14C] from SAM(S-adenosylmethionine)-[Me-14C] into precursors indicates the following sequence of tocopherol synthesis in spinach: 2-methyl-6-phytylquinol (6-phytyltoluquinol) (1a) .fwdarw. 2,3-dimethyl-5-phytylquinol (phytylplastoquinol) (2a) .fwdarw. .gamma.-tocopherol (5a) .fwdarw. .alpha.-tocopherol (6). 1a is particularly preferred to 2-methyl-5-phytylquinol (1b) and 2-methyl-3-phytylquinol (1c). 1a only forms 2a. 2a is converted to 6 via 5a and, to a lesser extent, 2,5-dimethyl-6-phylquinol (2b) to 6 via .beta.-tocopherol (5b). Trimethylphytylquinol (3) is not an intermediate in the formation of 6. All reactions are independent of light.

  DOI：

  10.1016/s0031-9422(00)81963-9
• 作为产物：
  描述：

  2-(丙-2-炔-1-基)己酸 在 甲醇 、 sodium tetrahydroborate 作用下， 反应 2.0h， 生成 2-methyl-5-phytylquinol
  参考文献：
  名称：

  2-Methyl-6-phytylquinol and 2,3-dimethyl-5-phytylquinol as precursors of tocopherol synthesis in spinach chloroplasts

  摘要：

  The incorporation of [Me(methyl)-14C] from SAM(S-adenosylmethionine)-[Me-14C] into precursors indicates the following sequence of tocopherol synthesis in spinach: 2-methyl-6-phytylquinol (6-phytyltoluquinol) (1a) .fwdarw. 2,3-dimethyl-5-phytylquinol (phytylplastoquinol) (2a) .fwdarw. .gamma.-tocopherol (5a) .fwdarw. .alpha.-tocopherol (6). 1a is particularly preferred to 2-methyl-5-phytylquinol (1b) and 2-methyl-3-phytylquinol (1c). 1a only forms 2a. 2a is converted to 6 via 5a and, to a lesser extent, 2,5-dimethyl-6-phylquinol (2b) to 6 via .beta.-tocopherol (5b). Trimethylphytylquinol (3) is not an intermediate in the formation of 6. All reactions are independent of light.

  DOI：

  10.1016/s0031-9422(00)81963-9

文献信息

• 2-Methyl-6-phytylquinol and 2,3-dimethyl-5-phytylquinol as precursors of tocopherol synthesis in spinach chloroplasts
  作者：Jürgen Soll、Gernot Schultz

  DOI：10.1016/s0031-9422(00)81963-9

  日期：1980.1

  The incorporation of [Me(methyl)-14C] from SAM(S-adenosylmethionine)-[Me-14C] into precursors indicates the following sequence of tocopherol synthesis in spinach: 2-methyl-6-phytylquinol (6-phytyltoluquinol) (1a) .fwdarw. 2,3-dimethyl-5-phytylquinol (phytylplastoquinol) (2a) .fwdarw. .gamma.-tocopherol (5a) .fwdarw. .alpha.-tocopherol (6). 1a is particularly preferred to 2-methyl-5-phytylquinol (1b) and 2-methyl-3-phytylquinol (1c). 1a only forms 2a. 2a is converted to 6 via 5a and, to a lesser extent, 2,5-dimethyl-6-phylquinol (2b) to 6 via .beta.-tocopherol (5b). Trimethylphytylquinol (3) is not an intermediate in the formation of 6. All reactions are independent of light.