trans-6,6a,7,8,9,9a-hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | 1392325-86-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: trans-6,6a,7,8,9,9a-hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
• 英文别名: 7,7,8,9,9-Pentamethyl-6,6a,7,8,9,9a-hexahydro-5H-cyclopenta(H)quinazoline；7,7,8,9,9-pentamethyl-6,6a,8,9a-tetrahydro-5H-cyclopenta[h]quinazoline
• CAS: 1392325-86-8
• 化学式: C₁₆H₂₄N₂
• 分子量: 244.38
• InChiKey: QKABJOXIAJBLQX-UHFFFAOYSA-N

物化性质

• 沸点：
  339℃ at 100.9kPa
• 密度：
  1.06 at 24℃
• LogP：
  4.1-5.84

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,1,2,3,3-pentamethyl-2,3,4,5-tetrahydro-1H-7,9-diaza-cyclopenta[a]naphthalene 在 palladium on activated charcoal 氢气 作用下， 以 异丙醇 为溶剂， 反应 4.0h， 生成 trans-6,6a,7,8,9,9a-hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline 、 trans-6,6a,7,8,9,9a-hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline
  参考文献：
  名称：

  Novel Quinazoline Compounds and Their Use in Perfume Compositions

  摘要：

  本发明涉及新型喹唑啉化合物及其在香水组合物中的应用。本发明的新型喹唑啉化合物由以下公式表示：其中，断裂线代表单键或双键的异构体或混合物。

  公开号：

  US20120207697A1

文献信息

• NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN PERFUME COMPOSITIONS
  申请人：International Flavors & Fragrances Inc.

  公开号：US20150057206A1

  公开（公告）日：2015-02-26

  The present invention relates to novel pyrimidine derivatives and their use in perfume compositions. The novel pyrimidine derivatives of the present invention are represented by the following formula: wherein m and n are integers of 0 or 1, with the proviso that when m is 0, n is 1 and when m is 1, n is 0; and wherein the dashed circle represents either single or double bonds.

  本发明涉及新型嘧啶衍生物及其在香水组合物中的使用。本发明的新型嘧啶衍生物由以下式子表示：其中m和n是0或1的整数，但当m为0时，n为1，当m为1时，n为0；其中虚线圆圈表示单键或双键。
• NOVEL QUINAZOLINE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS
  申请人：International Flavors & Fragrances Inc.

  公开号：US20140194339A1

  公开（公告）日：2014-07-10

  The present invention relates to novel quinazoline compounds and their use in perfume compositions. The novel quinazoline compounds of the present invention are represented by the following formula: an isomer or a mixture of isomers thereof, wherein the broken line represents a single or double bond.

  本发明涉及新型喹唑啉化合物及其在香水组合物中的应用。本发明的新型喹唑啉化合物由以下公式表示：其中，断裂的线表示单键或双键，可以是其异构体或异构体混合物。
• POLYALKOXY-POLYIMINE ADDUCTS FOR USE IN DELAYED RELEASE OF FRAGRANCE INGREDIENTS
  申请人：International Flavors & Fragrances Inc.

  公开号：EP3192566A1

  公开（公告）日：2017-07-19

  Disclosed is a fragrance adduct that is a reaction product between a polymeric amine and a reactive fragrance ingredient. The polymeric amine contains a backbone and at least one amino functional group, the reactive fragrance ingredient is an aldehyde, a ketone, an α,β-unsaturated electrophilic compound reactive towards the polymeric amine, or a combination thereof, and the reaction product is an imine compound or a Michael addition adduct. The fragrance adduct can be formulated into a fragrance composition, household product, personal care product, hair care product, or beauty care product. Also disclosed is a method for sequestering a fragrance using the fragrance adduct.

  本发明公开了一种香料加成物，它是聚合胺与活性香料成分的反应产物。聚合胺含有骨架和至少一个氨基官能团，反应性香料成分是醛、酮、对聚合胺有反应性的α,β-不饱和亲电化合物或它们的组合，反应产物是亚胺化合物或迈克尔加成加合物。该香料加合物可配制成香料组合物、家用产品、个人护理产品、护发产品或美容产品。此外，还公开了一种使用香料加合物封存香料的方法。
• Novel pyrimidine derivatives and their use in perfume compositions
  申请人：International Flavors & Fragrances Inc.

  公开号：EP2644688B1

  公开（公告）日：2017-11-08
• Novel quinazoline derivatives and their use in perfume compositions
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP2851415B1

  公开（公告）日：2016-04-27