threo-5-Fluoro-6-iododecane | 89609-00-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机碘化物
• 英文名称: threo-5-Fluoro-6-iododecane
• 英文别名: (5R,6R)-5-fluoro-6-iododecane
• CAS: 89609-00-7；89609-07-4
• 化学式: C₁₀H₂₀FI
• 分子量: 286.172
• InChiKey: AKBRNNALABDKBA-NXEZZACHSA-N

物化性质

• 沸点：
  74 °C(Press: 1 Torr)
• 密度：
  1.308±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  threo-5-Fluoro-6-iododecane 以32%的产率得到
  参考文献：
  名称：

  PANKOVA, M.;KOCIAN, O.;KRUPICKA, J.;ZAVADA, J., COLLECT. CZECH. CHEM. COMMUN., 1983, 48, N 10, 2944-2951

  摘要：

  DOI：
• 作为产物：
  描述：

  顺式-5-癸烯 在 iodine pentafluoride-pyridine-hydrogen fluoride 、 potassium iodide 作用下， 以 二氯甲烷 为溶剂， 反应 17.5h， 以58%的产率得到threo-5-Fluoro-6-iododecane
  参考文献：
  名称：

  Iodofluorination of Alkenes Using IF5–Pyridine–HF

  摘要：

  Iodofluorination of alkenes was performed by using IF5-pyridine-HF and a reductant such as potassium iodide or tin powder. The addition of IF to the double bond proceeded with stereo- and regioselectivity. In the reaction with internal alkenes, the trans-addition product was obtained selectively. With terminal alkenes, the addition took place regioselectively to give 1-iodo-2-fluoroalkanes.

  DOI：

  10.1055/s-0034-1381003

文献信息

• Pankova, Magdalena; Kocian, Oldrich; Krupicka, Josef, Collection of Czechoslovak Chemical Communications, 1983, vol. 48, # 10, p. 2944 - 2951
  作者：Pankova, Magdalena、Kocian, Oldrich、Krupicka, Josef、Zavada, Jiri

  DOI：——

  日期：——
• Iodofluorination of Alkenes Using IF5–Pyridine–HF
  作者：Shoji Hara、Shohei Yano

  DOI：10.1055/s-0034-1381003

  日期：——

  Iodofluorination of alkenes was performed by using IF5-pyridine-HF and a reductant such as potassium iodide or tin powder. The addition of IF to the double bond proceeded with stereo- and regioselectivity. In the reaction with internal alkenes, the trans-addition product was obtained selectively. With terminal alkenes, the addition took place regioselectively to give 1-iodo-2-fluoroalkanes.
• PANKOVA, M.;KOCIAN, O.;KRUPICKA, J.;ZAVADA, J., COLLECT. CZECH. CHEM. COMMUN., 1983, 48, N 10, 2944-2951
  作者：PANKOVA, M.、KOCIAN, O.、KRUPICKA, J.、ZAVADA, J.

  DOI：——

  日期：——