8-decylquinoline | 1303543-82-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 8-decylquinoline
• CAS: 1303543-82-9
• 化学式: C₁₉H₂₇N
• 分子量: 269.43
• InChiKey: LREOYSMSKCLLDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  喹啉 在 silver tetrafluoroborate 、 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 copper diacetate 、 溶剂黄146 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成 8-decylquinoline
  参考文献：
  名称：

  铑催化的活化和未活化烯烃对喹啉的远程C-8烷基化：机理研究和EP4激动剂的全合成

  摘要：

  本文报道的是铑（III）催化的区域选择性远侧C（SP 2）-H键的喹啉烷基化ñ -oxides使用烯烃作为烷基源和Ñ氧化物作为无痕引导组。该反应具有广泛的底物范围，对C-8位置具有出色的选择性，并且烷基化产物的收率高。通过合成EP4激动剂可以确定已开发的催化方案的实用性。在机理研究中，C-8烯烃化喹啉被确定为反应中间体，在存在铑（I）物种（反应过程中由铑（III）生成）和甲酸的情况下，该中间体还原为所需的C-8烷基化产物。在四氟硼酸银的存在下，由二甲基甲酰胺生产甲酸。

  DOI：

  10.1002/adsc.201700542

文献信息

• PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE
  申请人：Okamoto Kuniaki

  公开号：US20120130107A1

  公开（公告）日：2012-05-24

  Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R 1 's and T are as described in claim 1 ) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R 3 to R 5 are as described in claim 1 ), and a disulfonic acid ester represented by a general formula [1′] (in the formula, two R 16 's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).

  提供一种高效生产双季铵盐和其新型合成中间体的方法。本发明涉及一种生产由通用式[3]表示的双季铵盐的方法，包括将由通用式[1]表示的二磺酸酯（在该式中，两个R1和T的定义如权利要求1中所述）与由通用式[2]表示的三级胺（在该式中，R3到R5的定义如权利要求1中所述）以及由通用式[1']表示的二磺酸酯（在该式中，两个R16独立表示卤原子或C1-C3氟烷基，两个m独立表示1至5的整数）反应。
• Novel disulfonic acid ester as an additive for an electrolyte for a lithium secondary battery
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP2821395A2

  公开（公告）日：2015-01-07

  Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R1's and T are as described in Claim 1) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R3 to R5 are as described in Claim 1), and a novel disulfonic acid ester represented by a general formula [1'] (in the formula, two R16's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5) as an additive for an electrolyte for a lithium secondary battery.

  目的 提供一种高效生产双季铵盐的方法及其新型合成中间体。 本发明涉及一种生产通式[3]代表的双季铵盐的方法，该方法包括将通式[1]代表的二磺酸酯（式中，两个 R1 和 T 的定义如权利要求 1 所述）与通式[2]代表的叔胺（式中、R3至R5的定义如权利要求1所述），以及通式[1']代表的新型二磺酸酯（式中，两个R16独立地代表卤素原子或C1-C3氟烷基，两个m独立地代表1至5的整数），作为锂二次电池电解液的添加剂。
• Cross-couplings of alkyl halides with heteroaromatic halides, in water at room temperature
  作者：Arkady Krasovskiy、Isabelle Thomé、Julien Graff、Valeria Krasovskaya、Paul Konopelski、Christophe Duplais、Bruce H. Lipshutz

  DOI：10.1016/j.tetlet.2010.11.160

  日期：2011.4

  Zn-mediated, Pd-catalyzed cross-coupling reactions between heteroaromatic and alkyl halides can be done at room temperature in pure water using a commercially available Pd catalyst and PTS, a nanomicelle-forming amphiphile. Notably, zinc metal inserts selectively into a carbon sp(3)-halide bond, while palladium adds oxidatively to a carbon sp(2)-bond. (C) 2010 Elsevier Ltd. All rights reserved.
• US8716513B2
  申请人：——

  公开号：US8716513B2

  公开（公告）日：2014-05-06