2-羟基-1-苯基丁烷-1,3-二酮 | 18632-35-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-羟基-1-苯基丁烷-1,3-二酮
• 英文名称: 2-hydroxy-1-phenyl-butane-1,3-dione
• 英文别名: 2-Hydroxy-1-phenyl-butan-1,3-dion；2-Hydroxy-1-phenylbutane-1,3-dione
• CAS: 18632-35-4
• 化学式: C₁₀H₁₀O₃
• 分子量: 178.188
• InChiKey: DMHDAJCXNSEXEE-UHFFFAOYSA-N

物化性质

• 沸点：
  134-136 °C(Press: 11 Torr)
• 密度：
  1.196±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-羟基-1-苯基丁烷-1,3-二酮 、 苯肼 在 溶剂黄146 作用下， 生成 3-甲基-1,5-二苯基吡唑-4-醇
  参考文献：
  名称：

  Boehme; Schneider, Chemische Berichte, 1958, vol. 91, p. 1100,1105

  摘要：

  DOI：
• 作为产物：
  描述：

  2-chloro-1-phenylbutane-1,3-dione 在 盐酸 、 potassium acetate 作用下， 生成 2-羟基-1-苯基丁烷-1,3-二酮
  参考文献：
  名称：

  Boehme; Schneider, Chemische Berichte, 1958, vol. 91, p. 1100,1105

  摘要：

  DOI：

文献信息

• Enzymatic process for the preparation of butyrolactones
  申请人：Lonza Ltd

  公开号：EP2634180A1

  公开（公告）日：2013-09-04

  The invention relates to a process for the preparation of a compound of formula wherein R1 is selected from the group consisting of hydrogen, C2-11-acyl, C4-9-cycloalkanoyl, aryl, aralkyl, aroyl, hetaryl, hetaralkyl and hetaroyl, comprising a biotransformation of a compound of formula wherein R1 is as defined above, wherein said biotransformation is carried out using a polypeptide having aldo-keto reductase activity or a microorganism containing same.

  这项发明涉及一种制备下式化合物的方法 其中R1选自羟基、C2-11-酰基、C4-9-环烷酰基、芳基、芳基烷基、芳酰基、杂芳基、杂芳基烷基和杂芳酰基的群组，包括利用下式化合物的生物转化 其中R1如上定义，所述生物转化是利用具有醛酮还原酶活性的多肽或含有该多肽的微生物进行的。
• DDQ-mediated oxidation of sp3 C–H bond for the direct synthesis of vicinal tricarbonyl compounds
  作者：Zheng-Lin Wang、Xing-Lan An、Li-Shi Ge、Jing-Hai Jin、Xiaoyan Luo、Wei-Ping Deng

  DOI：10.1016/j.tet.2014.04.021

  日期：2014.6

  A facile and direct synthetic method was developed for the construction of vicinal tricarbonyl compounds (VTCs) in moderate to excellent yields (46-92%), by treating the readily available 1,3-dicarbonyl compounds with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). The reaction pathway involves the DDQ-mediated oxidative activation of sp(3) C-H bond and subsequent coupling to TEMPO to form the key intermediate TEMPO-substrate adduct, which can be further converted to VTC products promoted by DDQ (C) 2014 Elsevier Ltd. All rights reserved.
• US3985718A
  申请人：——

  公开号：US3985718A

  公开（公告）日：1976-10-12
• US4182873A
  申请人：——

  公开号：US4182873A

  公开（公告）日：1980-01-08
• [EN] FLAME RETARDANT POYLMER COMPOSITIONS<br/>[FR] COMPOSITIONS POLYMERIQUES IGNIFUGES
  申请人：BOEING CO

  公开号：WO2005071004A2

  公开（公告）日：2005-08-04

  A fire retardant polymer composition is provided. The fire retardant polymer composition is formed of a polymer material, a plurality of monomers of a polycondensed partially hydrolyzed chelated metal oxide precursor, and at least one flame retardant constituent. A process for making a flame retardant polymer composition is also presented. The process includes contacting a polymer material with a metal oxide sol comprising a liquid and a condensation product of a partially hydrolyzed chelated metal oxide precursor to form a mixture. The polymer material also is contacted with at least one flame retardant constituent. The polymer material is then polymerized or solidified.