(Z)-3,7-dimethyl-1,6-octadienyl acetate | 57576-60-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-3,7-dimethyl-1,6-octadienyl acetate
• 英文别名: (Z)-3,7-Dimethylocta-1,6-dienylacetat；[(1Z)-3,7-dimethylocta-1,6-dienyl] acetate
• CAS: 57576-60-0
• 化学式: C₁₂H₂₀O₂
• 分子量: 196.29
• InChiKey: UGXCOBMTQQHYSO-HJWRWDBZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  香茅醛 、 乙酸酐 在 sodium acetate 作用下， 生成 (Z)-3,7-dimethyl-1,6-octadienyl acetate
  参考文献：
  名称：

  Cant,P.A.E. et al., Australian Journal of Chemistry, 1975, vol. 28, p. 391 - 397

  摘要：

  DOI：

文献信息

• Aldehyde Enol Esters as Novel Chain Terminators in Cationic Olefin Cyclizations
  作者：Dana P. Simmons、Daniel Reichlin、David Skuy

  DOI：10.1002/hlca.19880710509

  日期：1988.8.10

  Citronella (1) has been transformed into enol acetates 2 which have been cyclized with various Lewis and Brönsted acids to dihydrocyclocitral (4). Application of this methodology to the synthesis of mono- and bicyclic ring systems has been examined.

  香茅油（1）已转化为烯醇乙酸酯2，已用各种路易斯酸和布朗斯台德酸环化成二氢环柠檬酸（4）。已经研究了该方法在单环和双环系统合成中的应用。
• COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS
  申请人：CASE WESTERN RESERVE UNIVERSITY

  公开号：US20170340581A1

  公开（公告）日：2017-11-30

  A method of treating an ocular disorder in a subject associated with increased all-trans-retinal in an ocular tissue includes administering to the subject a therapeutically effective amount of a primary amine compound of formula (I); and pharmaceutically acceptable salts thereof.
• [EN] COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS<br/>[FR] COMPOSÉS ET MÉTHODES DE TRAITEMENT DE TROUBLES OCULAIRES
  申请人：UNIV CASE WESTERN RESERVE

  公开号：WO2016085939A2

  公开（公告）日：2016-06-02

  A method of treating an ocular disorder in a subject associated with increased all-trans-retinal in an ocular tissue includes administering to the subject a therapeutically effective amount of a primary amine compound of formula (I); and pharmaceutically acceptable salts thereof.