3-十四烷基氧基丙胺 | 7617-82-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3-十四烷基氧基丙胺
• 英文名称: tetradecyloxypropyl amine
• 英文别名: 3-tetradecyloxy-1-propanamine；3-myristyloxypropylamine；3-(Tetradecyloxy)propylamine；3-tetradecoxypropan-1-amine
• CAS: 7617-82-5
• 化学式: C₁₇H₃₇NO
• 分子量: 271.487
• InChiKey: XIFDDGOEJJEZBQ-UHFFFAOYSA-N

物化性质

• 沸点：
  367.6±15.0 °C(Predicted)
• 密度：
  0.850±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  19
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  disodium epoxysuccinate 、 3-十四烷基氧基丙胺 生成 2-hydroxy-3-(3-tetradecoxypropylamino)butanedioic acid
  参考文献：
  名称：

  Amphoteric surfactants based upon epoxy succinic acid

  摘要：

  本发明涉及新化合物及其应用和制备过程。这些化合物是新型两性表面活性剂，每个羟基中含有一个羟基和两个羧基。这些化合物具有独特的结构，在每个氨基上具有多个羧基。这些新型聚合物的用途是作为个人护理、纺织和相关应用中的柔软、防缠结和调理剂。

  公开号：

  US06346648B1
• 作为产物：
  描述：

  3-tetradecyloxy-1-propanol 在 叠氮磷酸二苯酯 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 三苯基膦 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 31.17h， 生成 3-十四烷基氧基丙胺
  参考文献：
  名称：

  Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase

  摘要：

  N-Acylethanolamines (NAEs) including N-arachidonoylethanolamine (anandamide) and N-palmitoylethanolamine are endogenous lipid mediators. These molecules are degraded to the corresponding fatty acids and ethanolamine by fatty acid amide hydrolase (FAAH) or NAE-hydrolyzing acid amidase (NAAA). Lipophilic amines, especially pentadecylamine (2c) and tridecyl 2-aminoacetate (11b), were found to exhibit potent NAAA inhibitory activities (IC50 = 5.7 and 11.8 mu M), with much weaker effects on FAAH. These simple structures would provide a scaffold for further improvement in NAAA inhibitory activity. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2012.03.065

文献信息

• N,N'-dialkyl derivatives of polyhydroxyalkyl alkylenediamines
  申请人：Ford Edward Michael

  公开号：US20060013780A1

  公开（公告）日：2006-01-19

  Surfactant compositions containing compounds according to structure (I), and methods of making them, are disclosed. The compounds provide reduced dynamic and equilibrium surface tension, good solubility, moderate foaming, and good cleaning performance. The methods for making them involve reaction of N-(polyhydroxyalkyl)-alkylamines with dinitriles, dialdehydes, or acetals or hemiacetals of dialdehydes in the presence of hydrogen and a transition metal catalyst. In structure (I), x is an integer from about 1 to 12, R 1 and R 2 are independently C3-C30 linear alkyl, cyclic alkyl, branched alkyl, alkenyl, aryl, alkylaryl, alkoxyalkyl, and dialkylaminoalkyl; and R 3 and R 4 are independently hydrogen or a pyranosyl group such as α-D-glucopyranosyl, β-D-glucopyranosyl, or β-D-galactopyranosyl.

  含有结构（I）中化合物的表面活性剂组合物以及制备它们的方法已被披露。这些化合物提供了降低的动态和平衡表面张力、良好的溶解性、适度的起泡性能和良好的清洁性能。制备它们的方法涉及N-(多羟基烷基)-烷基胺与二腈、二醛或二醛的缩醛或半缩醛在氢气和过渡金属催化剂存在下的反应。在结构（I）中，x是约1到12之间的整数，R1和R2独立地为C3-C30线性烷基、环烷基、支链烷基、烯烃、芳基、烷基芳基、烷氧基烷基和二烷基氨基烷基；R3和R4独立地为氢或吡喃基团，如α-D-葡萄糖吡喃基、β-D-葡萄糖吡喃基或β-D-半乳糖吡喃基。
• Method for preserving quaternary ammonium salt
  申请人：——

  公开号：US20030153785A1

  公开（公告）日：2003-08-14

  A method of improving the stability of a quaternary ammonium salt and a method of efficiently preparing the quaternary ammonium salt having improved stability.

  一种提高季铵盐稳定性的方法和一种高效制备稳定性提高的季铵盐的方法。
• Process for producing unsaturated dicarboxylic acid imide compound
  申请人：MATSUSHITA ELECTRIC WORKS, LTD.

  公开号：EP0387381A1

  公开（公告）日：1990-09-19

  A process for producing an unsaturated di­carboxylic acid imide compound of formula (I): wherein D represents a divalent organic group having at least one carbon/carbon double bond; R¹ represents an n-­valent organic group having at least one carbon atom; and n is an integer of 1 or above, which comprises reacting an unsaturated amide acid compound of formula (II): wherein D, R¹, and n are as defined above, with an orthoester of formula (III): R²-C⁅OR³]₃      (III) wherein R² and R³, which may be the same or different, each represents a monovalent organic group having at least one carbon atom, to form an unsaturated dicarboxylic acid amide acid ester compound of formula (IV): wherein D, R¹, R³, and n are as defined above, and then imidating the compound of formula (IV).

  一种制备式（I）的不饱和二羧酸酰亚胺化合物的方法：其中D表示至少具有一个碳/碳双键的二价有机基团；R¹表示至少具有一个碳原子的n价有机基团；n为1或以上的整数；包括将式（II）的不饱和酰胺酸化合物与式（III）的正酯发生反应：R²-C⁅OR³]₃      （III），其中R²和R³，可以相同也可以不同，每个都表示至少具有一个碳原子的一价有机基团，形成式（IV）的不饱和二羧酸酰胺酸酯化合物：其中D，R¹，R³和n如上定义，然后对式（IV）的化合物进行亚胺化。
• Modified epoxy resin composition and process for the preparation thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0055632A1

  公开（公告）日：1982-07-07

  Modified epoxy resin composition having excellent flexibility and excellent compatibility with conventional epoxy resins as well as the original properties of the epoxy resin before modified such as mechanical strength, adhesion, heat resistance and chemical resistance, which is obtained by treating an epoxy resin with at least one modified adduct [D] of a conjugated diene polymer or copolymer which has an imido bond and/or amido bond and a semi-ester structure and has an acid value owing to a free carboxyl group of 5 to 100, the modified adduct being obtained by reacting an adduct [A] of a polymer of a conjugated diene having a number average molecular weight of 300 to 20,000 or a copolymer of the conjugated diene and a vinyl monomer with an α,β-unsaturated dicarboxylic acid or its anhydride, with a compound [B] containing one primary amino group in the molecule and a compound [C] containing a hydroxy group in the molecule.

  改性环氧树脂组合物，具有优异的柔韧性和与传统环氧树脂优异的相容性，以及改性前环氧树脂的原有性能，如机械强度、粘合性、耐热性和耐化学性，该组合物是用至少一种共轭二烯聚合物或共聚物的改性加合物[D]处理环氧树脂而得到的，共轭二烯聚合物或共聚物具有亚氨基键和/或氨基键和半酯结构，由于游离羧基而具有 5 至 100 的酸值、该改性加合物是将平均分子量为 300 至 20,000 的共轭二烯聚合物或共轭二烯与乙烯基单体的共聚物与α，β-不饱和二羧酸或其酐的加合物[A]，与分子中含有一个伯氨基的化合物[B]和分子中含有一个羟基的化合物[C]反应而得到的。
• Cyan dye-forming couplers and photographic recording materials containing same
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0443159A1

  公开（公告）日：1991-08-28

  Tetrahydroquinoline rings fused to a phenolic ring form novel cyan dye-forming coupler compounds which produce dyes having improved resistance to ferrous ion reduction. Photographic recording materials containing such coupler compounds are also disclosed.

  与酚醛环融合的四氢喹啉环形成了新颖的青色染料形成耦合剂化合物，其产生的染料具有更好的抗亚铁离子还原性。 此外，还公开了含有这种耦合化合物的照相记录材料。