6-Methanesulfonylmethyl-2,4,6-trimethyl-cyclohexa-2,4-dienone | 229008-08-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-Methanesulfonylmethyl-2,4,6-trimethyl-cyclohexa-2,4-dienone
• 英文别名: 2,4,6-Trimethyl-6-(methylsulfonylmethyl)cyclohexa-2,4-dien-1-one
• CAS: 229008-08-6
• 化学式: C₁₁H₁₆O₃S
• 分子量: 228.312
• InChiKey: UGURGPOGVVCHSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  59.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-Methanesulfonylmethyl-2,4,6-trimethyl-cyclohexa-2,4-dienone 以 四氢呋喃 、 水 为溶剂， 反应 7.0h， 以72%的产率得到(3Z,5E)-7-Methanesulfonyl-2,4,6-trimethyl-hepta-3,5-dienoic acid
  参考文献：
  名称：

  Photocleavage coupling reactions between cyclohexa-2,4-dienone sulfone derivatives and amines by visible light irradiation

  摘要：

  A stable sulfone derivative of 2,4,6-trimethylcyclohexa-2,4-diene-1-one (7) undergoes facile ring cleavage under visible light to produce a ketene intermediate, which could be efficiently captured by amines to give amides even in the presence of competing nucleophiles such as water and ethanol. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00153-5
• 作为产物：
  描述：

  2,4,6-三甲酚 在 N-氯代丁二酰亚胺 、 三乙胺 、 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 6-Methanesulfonylmethyl-2,4,6-trimethyl-cyclohexa-2,4-dienone
  参考文献：
  名称：

  Photocleavage coupling reactions between cyclohexa-2,4-dienone sulfone derivatives and amines by visible light irradiation

  摘要：

  A stable sulfone derivative of 2,4,6-trimethylcyclohexa-2,4-diene-1-one (7) undergoes facile ring cleavage under visible light to produce a ketene intermediate, which could be efficiently captured by amines to give amides even in the presence of competing nucleophiles such as water and ethanol. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00153-5

文献信息

• Photolytic Cleavage and Condensation Reactions of Cyclohexa-2,4-dienones with Diamines
  作者：Young Kim、Suk Song、Tae Kwon、Sung Chung

  DOI：10.3390/50700961

  日期：——

  Cyclohexa-2,4-diene-1-one sulfone derivate undergoes ring cleavage to afford bis-amides containing a diene moiety on irradiation with visible light in the presence of various diamines.

  环己-2,4-二烯-1-酮砜衍生物在各种二胺的存在下，经可见光照射后发生环裂解，生成含有二烯分子的双酰胺。