(1S,2R,5S,7S)-2,6,6-trimethyl-8-methylidenetricyclo[5.3.1.01,5]undecan-9-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1S,2R,5S,7S)-2,6,6-trimethyl-8-methylidenetricyclo[5.3.1.01,5]undecan-9-ol
• 化学式: C₁₅H₂₄O
• 分子量: 220.35
• InChiKey: DJYWGTBEZVORGE-WCRMDNNCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• USES OF SESQUITERPENE DERIVATIVES
  申请人：Kwang Dong Pharm. Co., Ltd.

  公开号：EP2331089A2

  公开（公告）日：2011-06-15
• US8481592B2
  申请人：——

  公开号：US8481592B2

  公开（公告）日：2013-07-09
• [EN] USES OF SESQUITERPENE DERIVATIVES<br/>[FR] UTILISATIONS DE DÉRIVÉS DE SESQUITERPÈNE
  申请人：IND ACADEMIC COOP

  公开号：WO2010030054A2

  公开（公告）日：2010-03-18

  The present invention relates to a pharmaceutical composition for preventing or treating hyperlipidemia, fatty liver, diabetes and obesity comprising a sesquiterpene derivative as an active ingredient. The sesquiterpene derivatives of the present invention leads to decrease in body fat weight, visceral fat weight and total cholesterol levels, triglyceride of plasma and liver tissue, blood glucose and blood insulin levels in a fast state, finally exhibiting efficacies on prevention or treatment of hyperlipidemia, fatty liver, diabetes and obesity.