(-)-olivil tetraacetate | 107783-49-3

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 呋喃类木脂素
• 英文名称: (-)-olivil tetraacetate
• CAS: 107783-49-3
• 化学式: C₂₈H₃₂O₁₁
• 分子量: 544.555
• InChiKey: NMRSVPRDBYHWRL-MWVDVNALSA-N

反应信息

• 作为反应物：
  描述：

  (-)-olivil tetraacetate 在 氨 作用下， 以 甲醇 为溶剂， 以13.9 mg的产率得到(-)-olivil diacetate
  参考文献：
  名称：

  杜仲树皮中木脂素苷对腺苷3'，5'-环磷酸单酯磷酸二酯酶的抑制作用。

  摘要：

  Studies were conducted on adenosine 3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterase inhibition by lignan glucosides from bark of Eucommia ulmoides OLIV. (Eucommiaceae). Various lignan diglucosides. (+)-syringaresinol di-O-β-D-glucopyranoside (1c), (+)-medioresinol di-O-β-D-glucopyranoside (2c), (+)-pinoresinol di-O-β-D-glucopyranoside (3c) and (+)-1-hydroxy-pinoresinol 4', 4"-di-O-β-D-glucopyranoside (4d), showed strong inhibitory activity.The structure-inhibitory activity relationships of the aglycone and its glucosides are discussed. The order of inhibitory effect was diglucoside ≩︀ aglycone > monoglucoside.

  DOI：

  10.1248/cpb.36.435
• 作为产物：
  描述：

  乙酸酐 、 橄榄树脂素 在 吡啶 作用下， 以27 mg的产率得到(-)-olivil tetraacetate
  参考文献：
  名称：

  杜仲树皮中木脂素苷对腺苷3'，5'-环磷酸单酯磷酸二酯酶的抑制作用。

  摘要：

  Studies were conducted on adenosine 3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterase inhibition by lignan glucosides from bark of Eucommia ulmoides OLIV. (Eucommiaceae). Various lignan diglucosides. (+)-syringaresinol di-O-β-D-glucopyranoside (1c), (+)-medioresinol di-O-β-D-glucopyranoside (2c), (+)-pinoresinol di-O-β-D-glucopyranoside (3c) and (+)-1-hydroxy-pinoresinol 4', 4"-di-O-β-D-glucopyranoside (4d), showed strong inhibitory activity.The structure-inhibitory activity relationships of the aglycone and its glucosides are discussed. The order of inhibitory effect was diglucoside ≩︀ aglycone > monoglucoside.

  DOI：

  10.1248/cpb.36.435