6,11-bis-bromomethyl-2,15-dimethyl-hexadeca-2,4,6,8,10,12,14-heptaenedial | 56218-20-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 6,11-bis-bromomethyl-2,15-dimethyl-hexadeca-2,4,6,8,10,12,14-heptaenedial
• 英文别名: (all-Ξ)-20,20'-dibromo-8,8'-diapo-carotene-8,8'-dial；6,11-Bis(bromomethyl)-2,15-dimethylhexadeca-2,4,6,8,10,12,14-heptaenedial
• CAS: 56218-20-3
• 化学式: C₂₀H₂₂Br₂O₂
• 分子量: 454.201
• InChiKey: FPBQBYTVCHFGQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,6,11,15-tetramethylhexadec-2,4,6,8,10,12,14-heptenedial 在 N-溴代丁二酰亚胺(NBS) 作用下， 生成 6,11-bis-bromomethyl-2,15-dimethyl-hexadeca-2,4,6,8,10,12,14-heptaenedial
  参考文献：
  名称：

  Johansen,J.E.; Liaaen-Jensen,S., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1975, vol. 29, p. 315 - 319

  摘要：

  DOI：

文献信息

• CAROTENOID OXIDATION PRODUCTS AS CHEMOPREVENTIVE AND CHEMOTHERAPEUTIC AGENTS
  申请人：Sharoni Yoav

  公开号：US20090069417A1

  公开（公告）日：2009-03-12

  The present invention relates to a method for the chemoprevention and treatment of cancer, by administering a pharmaceutical composition comprising a carotenoid derivative, such as a derivative of lycopene, a- and b-carotene, phytoene, phytofluene, lutein, zeaxanthin, α- and β-cryptoxanthin, canthaxanthin, astaxanthin, or other carotenoid. The carotenoid derivative is a carotenoid oxidation product, and is preferably an aldehyde derivative, a dialdehyde derivative or a ketone derivative. The carotenoid derivative can be a derivative of any naturally occurring carotenoid, such as those found in tomatoes and other fruits and vegetables.
• Johansen,J.E.; Liaaen-Jensen,S., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1975, vol. 29, p. 315 - 319
  作者：Johansen,J.E.、Liaaen-Jensen,S.

  DOI：——

  日期：——