(1R,2R,6S,7S)-5-((R)-2-Methyl-3-phenyl-propionyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one | 139174-22-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,2R,6S,7S)-5-((R)-2-Methyl-3-phenyl-propionyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one
• CAS: 139174-22-4
• 化学式: C₁₈H₂₁NO₃
• 分子量: 299.37
• InChiKey: JGXILWBOQFPWKM-MBEZOWKRSA-N

反应信息

• 作为产物：
  描述：

  溴甲苯 、 (1R,2R,6S,7S)-5-Propionyl-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one 在 lithium diisopropyl amide 作用下， 生成 (1R,2R,6S,7S)-5-((R)-2-Methyl-3-phenyl-propionyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one 、 (1R,2R,6S,7S)-5-((S)-2-Methyl-3-phenyl-propionyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]decan-4-one
  参考文献：
  名称：

  Conformationally rigid chiral [4+2]cycloadduct-based 2-oxazolidinones as new auxiliaries

  摘要：

  Newly introduced enantiomerically pure [4 + 2]cycloadduct-based 2-oxazolidinones which are conformationally fixed by bicyclo[2.2.2] and [2.2.1] ring systems, serve well as exellent chiral auxiliaries in the Evans' asymmetric strategy.

  DOI：

  10.1016/0040-4039(91)80573-o