7α-hydroxy-14α,15α-epoxy-fridogammaceran-3-one | 134028-26-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 7α-hydroxy-14α,15α-epoxy-fridogammaceran-3-one
• CAS: 134028-26-5
• 化学式: C₃₀H₄₈O₃
• 分子量: 456.709
• InChiKey: YRZYEANXNWDVCO-LJCRIHPASA-N

反应信息

• 作为产物：
  描述：

  swertanone 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 72.0h， 以38%的产率得到swerta-7,9(11)-dien-3-one
  参考文献：
  名称：

  Peracid oxidation products of swertanone, the novel triterpene of Swertia chirata

  摘要：

  While treatment of swertanone (1a) with mineral acids and Lewis acids yielded isoswertanone (2a) as the only isolable product, its reaction with m-chloroperbenzoic acid afforded 7-alpha, 8-alpha-epoxyswertanone (7), 7-alpha -hydroxy-swert-8-en-3-one (8), swerta-7, 9(11)-dien-3-one (3a), its 7-alpha, 8-alpha -epoxide (4a), 7-alpha -hydroxy-friedogammacer-14-en-3-one (5a) and its 14-alpha, 15-alpha -epoxide (6a). The structures of the products have been elucidated mainly on the basis of H-1 and C-13 NMR spectroscopy and, in some cases, by chemical correlation.Assignments of C-13 NMR signals of the products have been done and those of some of the signals of 1a, swertenyl acetate (1b) and swertenol (16) have been revised. In this connection, spectra of bauerenyl acetate (18), isobauerenyl acetate (19) and multiflorenyl acetate (20) have been recorded.

  DOI：

  10.1016/s0040-4020(01)96141-1