2-chloro-1-(3,5-dichlorophenyl)-2,2-difluoroethanone | 864725-56-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-chloro-1-(3,5-dichlorophenyl)-2,2-difluoroethanone
• 英文别名: 2,3',5'-trichloro-2,2-difluoroacetophenone
• CAS: 864725-56-4
• 化学式: C₈H₃Cl₃F₂O
• 分子量: 259.467
• InChiKey: WMJBSIUHXDANQK-UHFFFAOYSA-N

物化性质

• 沸点：
  295.9±40.0 °C(Predicted)
• 密度：
  1.551±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-chloro-1-(3,5-dichlorophenyl)-2,2-difluoroethanone 在 potassium tert-butylate 、 碳酸氢钠 作用下， 以 四氢呋喃 、 乙酸乙酯 为溶剂， 反应 32.0h， 生成 ethyl 5-[chloro(difluoro)methyl]-5-(3,5-dichlorophenyl)-4H-isoxazole-3-carboxylate
  参考文献：
  名称：

  [EN] SUBSTITUTED ISOXAZOLINE DERIVATIVES
  [FR] DÉRIVÉS D'ISOXAZOLINE SUBSTITUÉS

  摘要：

  The invention relates to isoxazoline compounds of formula (I) wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their use for protecting growing plants and animals from attack or infestation by invertebrate pests, furthermore, to seed comprising such compounds.

  公开号：

  WO2022171472A1
• 作为产物：
  描述：

  2-氯-2,2-二氟乙酸甲酯 、 3,5-二氯碘苯 在 乙酸乙酯 、 magnesium sulfate 作用下， 以 甲基叔丁基醚 、 正丁基锂 、 氯化铵 为溶剂， 反应 1.0h， 以to obtain 4.6 g of crude aimed product as pale yellow oily substance的产率得到2-chloro-1-(3,5-dichlorophenyl)-2,2-difluoroethanone
  参考文献：
  名称：

  Isoxazoline-substituted benzamide compound and pesticide

  摘要：

  一种公式（1）的异氧唑基取代苯甲酰胺化合物或其盐： 其中A1，A2和A3各自独立地是碳原子或氮原子，G是苯环等，X是卤素原子，C1-C6卤代烷基等，Y是卤素原子，C1-C6烷基等，R1是任意取代R16的C1-C12烷基，任意取代R16的C3-C2烯基，是氧原子或硫原子，-N（R20）R19等，R2是氢原子，C1-C4烷氧基C1-C6烷基等，R3是C1-C6卤代烷基等，R16是卤素原子，氰基，被（Z）p1，D-1到D-60，E-1到E-49等取代的苯基，R19是苯基，被（Z）p1等取代的苯基，R20是氢原子，C1-C6烷基等，Z是卤素原子，硝基，C1-C4烷氧基等，D-1到D-60是5-或6-成员芳香杂环环，E-1到E-49是5-或6-成员饱和杂环环，m是0到5的整数，n是0到4的整数，p1是1到5的整数。包含这些化合物的杀虫剂。

  公开号：

  US07662972B2

文献信息

• ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE
  申请人：Mita Takeshi

  公开号：US20090312330A1

  公开（公告）日：2009-12-17

  An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A 1 , A 2 and A 3 independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., X is halogen atom, C 1 -C 6 haloalkyl, etc., Y is halogen atm, C 1 -C 6 alkyl, etc., R 1 is C 1 -C 12 alkyl arbitrarily substituted with R 16 , C 3 -C 12 alkenyl, arbitrarily substituted with R 16 is oxygen atom or sulfur atom, —N(R 20 )R 19 , etc., R 2 is hydrogen atom, C 1 -C 4 alkoxy C 1 -C 6 alkyl, etc., R 3 is C 1 -C 6 haloalkyl, etc., R 16 is halogen atom, cyano, phenyl substituted with (Z) p1 , D-1 to D-60, E-1 to E-49, etc., R 19 is phenyl, phenyl substituted with (Z) p1 , etc., R 20 is hydrogen atom, C 1 -C 6 alkyl, etc., Z is halogen atom, nitro, C 1 -C 4 alkoxy, etc., D-1 to D-60 are 5- or 6-membered aromatic heterocyclic rings, E-1 to E-49 are 5- or 6-membered saturated heterocyclic rings, m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

  一种公式（1）的异氧杂环取代苯甲酰胺化合物或其盐： 其中，A1，A2和A3独立地是碳原子或氮原子，G是苯环等，X是卤素原子，C1-C6卤代烷基等，Y是卤素原子，C1-C6烷基等，R1是任意取代R16的C1-C12烷基，任意取代R16的C3-C12烯基，是氧原子或硫原子，-N（R20）R19等，R2是氢原子，C1-C4烷氧基C1-C6烷基等，R3是C1-C6卤代烷基等，R16是卤素原子，氰基，苯基，其上取代有（Z）p1，D-1至D-60，E-1至E-49等，R19是苯基，其上取代有（Z）p1等，R20是氢原子，C1-C6烷基等，Z是卤素原子，硝基，C1-C4烷氧基等，D-1至D-60是5-或6-成员芳香杂环，E-1至E-49是5-或6-成员饱和杂环，m是0至5的整数，n是0至4的整数，p1是1至5的整数。含有这些化合物的杀虫剂。
• ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP1731512B9

  公开（公告）日：2017-03-01
• HOCHMOLEKULARE UNPOLARE BENZTRIAZOLE
  申请人：BASF SE

  公开号：EP2430089A2

  公开（公告）日：2012-03-21
• METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20170233321A1

  公开（公告）日：2017-08-17

  There is provided a novel intermediate for producing pesticides. A method for producing the compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4) and a substituted acetophenone compound of Formula (5) as starting raw materials in an organic solvent or water in the presence or absence of an additive in the presence of a base in a suspended state. A method may comprise dehydrating the compound of Formula (3). A method for producing compound (2) in one step comprises reacting compound (4) and compound (5) to obtain compound (3). Further, a method for producing an isoxazoline compound of Formula (1) comprises reacting compound (2) and a hydroxylamine in an aliphatic or an aromatic hydrocarbon solvent which is optionally substituted by a halogen atom by adding an additive selected from a phase-transfer catalyst, a C 1 -C 6 alcohol and an aprotic polar solvent in the presence of a base and water.
• US7662972B2
  申请人：——

  公开号：US7662972B2

  公开（公告）日：2010-02-16