chilianoside H | 222541-60-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: chilianoside H
• 英文别名: (2R,3R,4S,5S,6R)-2-[[(1S,2R,3R,5S,8R,9S,10R,13R,14R,17S)-17-[(2R)-2,5-dihydroxy-6-methylhept-6-en-2-yl]-1,2-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 222541-60-8
• 化学式: C₃₆H₆₂O₁₀
• 分子量: 654.882
• InChiKey: MFYBZVKJMFAPNF-JIPZFDOESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  46
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  180
• 氢给体数：
  8
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 chilianoside H 在 吡啶 作用下， 以9 mg的产率得到[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-[[(1S,2R,3R,5S,8R,9S,10R,13R,14R,17S)-2-acetyloxy-17-[(2R)-5-acetyloxy-2-hydroxy-6-methylhept-6-en-2-yl]-1-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-2-yl]methyl acetate
  参考文献：
  名称：

  Dammarane-Type Triterpene Glycosides from the Leaves of Rhoiptelea chiliantha.

  摘要：

  In the course of our continuing studies on the chemical constituents of Rhoipteleaceae from the chemotaxonomical point of view, twelve dammarane-type triterpene glycosides, chilianosides A-L, were isolated from the leaves of Rhoiptelea chiliantha DIELS et Hand.-MAZZ. (Rhoipteleaceae). Their structures were elucidated on the basis of spectral and chemical evidence. Chilianosides B-G possess hydroperoxyl groups in the molecules, whereas chilianosides H-L are the hydroxyl analogues of chilianosides B-G. All of the chilianosides have 20-R configurations.

  DOI：

  10.1248/cpb.47.257
• 作为产物：
  描述：

  chilianoside A 在 rose bengal 、 三苯基膦 作用下， 以 甲醇 为溶剂， 反应 14.0h， 生成 chilianoside H
  参考文献：
  名称：

  Dammarane-Type Triterpene Glycosides from the Leaves of Rhoiptelea chiliantha.

  摘要：

  In the course of our continuing studies on the chemical constituents of Rhoipteleaceae from the chemotaxonomical point of view, twelve dammarane-type triterpene glycosides, chilianosides A-L, were isolated from the leaves of Rhoiptelea chiliantha DIELS et Hand.-MAZZ. (Rhoipteleaceae). Their structures were elucidated on the basis of spectral and chemical evidence. Chilianosides B-G possess hydroperoxyl groups in the molecules, whereas chilianosides H-L are the hydroxyl analogues of chilianosides B-G. All of the chilianosides have 20-R configurations.

  DOI：

  10.1248/cpb.47.257