N-(4-nitrophenyl)-N'-quinolin-8-ylethane-1,2-diamine | 1313524-50-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(4-nitrophenyl)-N'-quinolin-8-ylethane-1,2-diamine
• CAS: 1313524-50-3
• 化学式: C₁₇H₁₆N₄O₂
• 分子量: 308.34
• InChiKey: SATVEJPBHWBRIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  82.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N-(4-nitrophenyl)-2-(quinolin-8-ylamino)acetamide 在 dimethyl sulfide borane 作用下， 以 四氢呋喃 为溶剂， 反应 12.5h， 以46%的产率得到N-(4-nitrophenyl)-N'-quinolin-8-ylethane-1,2-diamine
  参考文献：
  名称：

  Fine tuning of receptor polarity for the development of selective naked eye anion receptor

  摘要：

  We designed and synthesized new anion receptors 1, 2, and 3, which have different N-H polarity. According to their N-H polarities, these receptors showed different selectivities for the anions they were interacting with. The difference of selectivity could be easily recognized from their color change during recognition events. Therefore, fine tuning of receptor polarity could be a good strategy for the designing of a selective anion receptor and made it possible to develop a selective naked eye anion receptor. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.04.081

文献信息

• Fine tuning of receptor polarity for the development of selective naked eye anion receptor
  作者：Jin Joo Park、Young-Hee Kim、Cheal Kim、Jongmin Kang

  DOI：10.1016/j.tetlet.2011.04.081

  日期：2011.6

  We designed and synthesized new anion receptors 1, 2, and 3, which have different N-H polarity. According to their N-H polarities, these receptors showed different selectivities for the anions they were interacting with. The difference of selectivity could be easily recognized from their color change during recognition events. Therefore, fine tuning of receptor polarity could be a good strategy for the designing of a selective anion receptor and made it possible to develop a selective naked eye anion receptor. (C) 2011 Elsevier Ltd. All rights reserved.