(3bR,6aS)-7-Phenyl-1,2,3,3b,4,5,6,6a-octahydro-cyclopenta[a]pentalene-3a-carboxylic acid methyl-phenyl-amide | 135190-91-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (3bR,6aS)-7-Phenyl-1,2,3,3b,4,5,6,6a-octahydro-cyclopenta[a]pentalene-3a-carboxylic acid methyl-phenyl-amide
• 英文别名: (3aR,7aS)-N-methyl-N,7-diphenyl-1,2,3,3a,4,5,6,7a-octahydrocyclopenta[a]pentalene-3b-carboxamide
• CAS: 135190-91-9
• 化学式: C₂₅H₂₇NO
• 分子量: 357.495
• InChiKey: ICXLNORFNZZTHO-SXNCYPNXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-(2-iodophenyl)-N-methyl-2-(2-cyclopentenyl)-7-phenyl-6-heptynamide 在 偶氮二异丁腈 、 三正丁基氢锡 作用下， 以 苯 为溶剂， 以35%的产率得到(3bR,6aS)-7-Phenyl-1,2,3,3b,4,5,6,6a-octahydro-cyclopenta[a]pentalene-3a-carboxylic acid methyl-phenyl-amide
  参考文献：
  名称：

  Radical translocation reactions of o-iodoanilides: the use of carbon-hydrogen bonds as precursors of radicals adjacent to carbonyl groups

  摘要：

  The treatment of o-iodoanilides with tributyltin hydride results in radical generation followed by rapid translocation to produce radicals adjacent to carbonyls. These radicals participate in cyclization and asymmetric addition reactions.

  DOI：

  10.1021/jo00014a001

文献信息

• Radical translocation reactions of o-iodoanilides: the use of carbon-hydrogen bonds as precursors of radicals adjacent to carbonyl groups
  作者：Dennis P. Curran、Ann C. Abraham、Hongtao Liu

  DOI：10.1021/jo00014a001

  日期：1991.7

  The treatment of o-iodoanilides with tributyltin hydride results in radical generation followed by rapid translocation to produce radicals adjacent to carbonyls. These radicals participate in cyclization and asymmetric addition reactions.