6-Aminobicyclo[2.2.1]heptan-2-ol | 223595-58-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 6-Aminobicyclo[2.2.1]heptan-2-ol
• CAS: 223595-58-2
• 化学式: C₇H₁₃NO
• mdl: MFCD18826801
• 分子量: 127.18
• InChiKey: BBLGFSOKWOCPFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] AMINO QUINOLINE DERIVATIVES INHIBITORS OF HCV<br/>[FR] DÉRIVÉS D'AMINO-QUINOLÉINE INHIBITEURS DE VHC
  申请人：GILEAD SCIENCES INC

  公开号：WO2013090929A1

  公开（公告）日：2013-06-20

  A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents are defined herein, and methods of treating HCV infection in a patient are disclosed.

  一种化合物的化学式I：或其药用可接受的盐，其中取代基在此定义，并公开了治疗患者HCV感染的方法。
• Anti-vascular and anti-proliferation methods, therapies, and combinations employing specific tyrosine kinase inhibitors
  申请人：Nesbit Mark

  公开号：US20070197538A1

  公开（公告）日：2007-08-23

  This invention is directed to potent inhibitors of protein tyrosine kinase alone or in synergistic combination with antiangiogenic or chemotherapeutic agents for the abrogation of mature vasculature within chemotherapeutic refractory tumors, pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cell proliferation, and particularly treatment of brain cancer, ovarian cancer, pancreatic cancer prostate cancer, and human leukemias, such as CML, AML or ALL.

  本发明涉及针对蛋白酪氨酸激酶的强效抑制剂，单独或与抗血管生成或化疗药物协同使用，用于消除化疗难治性肿瘤内的成熟血管，以及包含这些化合物的制药组合物，并且用于治疗患有或患有涉及细胞增殖的疾病/病症的患者，特别是治疗脑癌、卵巢癌、胰腺癌、前列腺癌和人类白血病，如慢性髓细胞白血病、急性髓细胞白血病或急性淋巴细胞白血病。
• Compositions and Methods for the Isolation of Biologically Active Proteins
  申请人：Forman Henry J.

  公开号：US20100221809A1

  公开（公告）日：2010-09-02

  This invention is directed to compositions and methods for the isolation and further characterization of eukaryotic, mammalian, and/or human PC-PLC. In addition, the present invention discloses methods for the synthesis of an affinity chromatography resin for the isolation and purification of biologically active proteins, including eukaryotic PC-PLC.
• US6245760B1
  申请人：——

  公开号：US6245760B1

  公开（公告）日：2001-06-12