4-(triethylsilyloxy)cyclohexanol | 1094026-91-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-(triethylsilyloxy)cyclohexanol
• 英文别名: 4-triethylsilyloxycyclohexan-1-ol
• CAS: 1094026-91-1
• 化学式: C₁₂H₂₆O₂Si
• 分子量: 230.423
• InChiKey: JFCBQFLFJBVZHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.31
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(triethylsilyloxy)cyclohexanol 在 potassium peroxymonosulfate 、 2-碘苯磺酸钠 、 sodium sulfate 作用下， 以 乙酸乙酯 为溶剂， 反应 8.0h， 以74%的产率得到4-(triethylsilyloxy)cyclohexanone
  参考文献：
  名称：

  METHOD FOR PRODUCING CARBONYL COMPOUND AND PRO-OXIDANT USED FOR PRODUCTION OF CARBONYL COMPOUND

  摘要：

  公开号：

  EP2085373B8
• 作为产物：
  描述：

  三乙基氯硅烷 、 1,4-环己二醇 在 咪唑 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以54%的产率得到4-(triethylsilyloxy)cyclohexanol
  参考文献：
  名称：

  Uyanik, Muhammet; Akakura, Matsujiro; Ishihara, Kazuaki, Journal of the American Chemical Society, 2009, vol. 131, p. 251 - 262

  摘要：

  DOI：

文献信息

• PROCESS FOR PREPARATION OF CARBONYL COMPOUND AND PRO-OXIDANT FOR PREPARATION OF CARBONYL COMPOUND
  申请人：Ishihara Kazuaki

  公开号：US20100041917A1

  公开（公告）日：2010-02-18

  The invention provides a process for the preparation of a carbonyl compound in high efficiency by oxidizing an alcohol. The process for the preparation of a carbonyl compound of the present invention includes a step of oxidizing an alcohol in the presence of a compound of the formula (I) or a derivative or a salt thereof, and an oxidant, wherein R 1 and R 2 independently represent hydrogen, a halogen, a nitro or acidic group, or an alkyl or alkoxy group, each of which optionally has a substituent, or R 1 and R 2 combine the two carbon atoms to which they are boned to form an aromatic ring.

  本发明提供了一种通过氧化醇类化合物高效制备羰基化合物的方法。本发明的制备羰基化合物的方法包括在化合物(I)的衍生物或盐及氧化剂的存在下氧化醇类化合物的步骤，其中R1和R2分别独立地表示氢、卤素、硝基或酸性基团或烷基或烷氧基，每个基团可选地具有取代基，或者R1和R2结合形成它们所结合的两个碳原子形成芳环。
• Process for preparation of carbonyl compound and pro-oxidant for preparation of carbonyl compound
  申请人：Ishihara Kazuaki

  公开号：US08394995B2

  公开（公告）日：2013-03-12

  The invention provides a process for the preparation of a carbonyl compound in high efficiency by oxidizing an alcohol. The process for the preparation of a carbonyl compound of the present invention includes a step of oxidizing an alcohol in the presence of a compound of the formula (I) or a derivative or a salt thereof, and an oxidant, wherein R1 and R2 independently represent hydrogen, a halogen, a nitro or acidic group, or an alkyl or alkoxy group, each of which optionally has a substituent, or R1 and R2 combine the two carbon atoms to which they are boned to form an aromatic ring.

  本发明提供了一种通过氧化醇制备高效的羰基化合物的方法。本发明的羰基化合物制备方法包括在化合物(I)的存在下或其衍生物或盐的存在下，在氧化剂的存在下，将醇氧化的步骤，其中R1和R2分别表示氢、卤素、硝基或酸性基团，或烷基或烷氧基，每个基团都可以有取代基，或者R1和R2结合成它们所结合的两个碳原子形成一个芳环。
• Highly Efficient Cu(I)-Catalyzed Oxidation of Alcohols to Ketones and Aldehydes with Diaziridinone
  作者：Yingguang Zhu、Baoguo Zhao、Yian Shi

  DOI：10.1021/ol303431h

  日期：2013.3.1

  A novel and efficient Cu(I)-catalyzed oxidation of alcohols has been achieved with di-tert-butyldiaziridinone as the oxidant under mild conditions. A wide variety of primary and secondary alcohols with various functional groups can be oxidized to aldehydes and ketones in high yields. The reaction proceeds under neutral conditions making it compatible with acid- or base-sensitive substrates, and it is amenable to gram scale.
• 2-Iodoxy-5-Methylbenzenesulfonic Acid-Catalyzed Selective Oxidation of 4-Bromobenzyl Alcohol to 4-Bromobenzaldehyde or 4-Bromobenzoic Acid with Oxone
  作者：Uyanik, Muhammet、Kazuaki, Kazuaki

  DOI：10.15227/orgsyn.089.0105

  日期：——