27-氧夫西地酸 | 1415035-94-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 27-氧夫西地酸
• 中文别名: 夫西地酸杂质
• 英文名称: 26-Oxofusidic Acid
• 英文别名: (E,2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methyl-7-oxohept-5-enoic acid
• CAS: 1415035-94-7
• 化学式: C₃₁H₄₆O₇
• 分子量: 530.7
• InChiKey: OZMOUWFCJHVIQT-CEDPPNKGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  38
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  121
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• COMPOSITIONS COMPRISING FUSIDIC ACID AND PACKAGES THEREFOR
  申请人：Pereira David E.

  公开号：US20140088062A1

  公开（公告）日：2014-03-27

  Described are solid pharmaceutical compositions of fusidic acid, and pharmaceutically acceptable salts thereof, dosage units of the pharmaceutical compositions, and packages for pharmaceutical compositions of fusidic acid, and pharmaceutically acceptable salts thereof, which increase stability against the degradation of the fusidic acid, and pharmaceutically acceptable salts thereof. Also described are uses of the pharmaceutical compositions and dosage units in treating diseases.