(1R,5R,6S,7S,10R)-10-methyl-4-methylene-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-5,6-epoxy-decahydro-naphthalene | 1224700-90-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,5R,6S,7S,10R)-10-methyl-4-methylene-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-5,6-epoxy-decahydro-naphthalene
• CAS: 1224700-90-6
• 化学式: C₂₁H₃₈O₂Si
• 分子量: 350.617
• InChiKey: XTRVIARBLWFXGD-LBFCPWMRSA-N

反应信息

• 作为反应物：
  描述：

  (1R,5R,6S,7S,10R)-10-methyl-4-methylene-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-5,6-epoxy-decahydro-naphthalene 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 以90%的产率得到(1R,5R,6S,7S,10R)-10-methyl-4-methylene-7-(1-methylethyl)-5,6-epoxy-decahydro-naphthalene-1-ol
  参考文献：
  名称：

  First total synthesis of (+)-Carainterol A

  摘要：

  The first, stereospecific, and elegant synthesis of the natural product (+)-Carainterol A was developed by using the Robinson annulation reaction as a key step to build the eudesmane skeleton. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.02.001
• 作为产物：
  描述：

  在 sodium hydroxide 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 1.0h， 以58%的产率得到(1R,5R,6S,7S,10R)-10-methyl-4-methylene-7-(1-methylethyl)-1-[(tert-butyldimethylsilyl)oxy]-5,6-epoxy-decahydro-naphthalene
  参考文献：
  名称：

  First total synthesis of (+)-Carainterol A

  摘要：

  The first, stereospecific, and elegant synthesis of the natural product (+)-Carainterol A was developed by using the Robinson annulation reaction as a key step to build the eudesmane skeleton. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.02.001