(1R,2S,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl 2-phenyl-2-(2-tosylhydrazineylidene)acetate | 161634-48-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,2S,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl 2-phenyl-2-(2-tosylhydrazineylidene)acetate
• CAS: 161634-48-6
• 化学式: C₃₁H₃₆N₂O₄S
• 分子量: 532.704
• InChiKey: MQFZROKOGIJPDD-XTBZXYEFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.0
• 重原子数：
  38.0
• 可旋转键数：
  8.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  84.83
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  (1R,2S,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl 2-phenyl-2-(2-tosylhydrazineylidene)acetate 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 (-)-(1R,3R,4S)-8-phenylmenthyl 2-diazo-2-phenylacetate
  参考文献：
  名称：

  Diastereoselectivity in the OH insertion reactions of rhodium carbenoids derived from phenyldiazoacetates of homochiral alcohols

  摘要：

  Rhodium(II) acetate catalysed decomposition of the phenyldiazoacetates 3 in the presence of alcohols (methanol, propan-2-ol, tert-butanol) led to the O-II insertion products 4-6 in varying yields; the diastercomeric excess of the product ranged from 5-53%.

  DOI：

  10.1016/s0040-4039(00)78227-x
• 作为产物：
  描述：

  Phenylglyoxylsaeure-<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)-1-cyclohexyl>ester 、 对甲苯磺酰肼 以 甲苯 为溶剂， 生成 (1R,2S,5R)-5-methyl-2-(2-phenylpropan-2-yl)cyclohexyl 2-phenyl-2-(2-tosylhydrazineylidene)acetate
  参考文献：
  名称：

  Diastereoselectivity in the OH insertion reactions of rhodium carbenoids derived from phenyldiazoacetates of homochiral alcohols

  摘要：

  Rhodium(II) acetate catalysed decomposition of the phenyldiazoacetates 3 in the presence of alcohols (methanol, propan-2-ol, tert-butanol) led to the O-II insertion products 4-6 in varying yields; the diastercomeric excess of the product ranged from 5-53%.

  DOI：

  10.1016/s0040-4039(00)78227-x