2-amino-3,5,5-trimethylcyclohex-2-en-1-one | 57696-95-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-amino-3,5,5-trimethylcyclohex-2-en-1-one
• CAS: 57696-95-4
• 化学式: C₉H₁₅NO
• 分子量: 153.224
• InChiKey: XQTBXOPVEMBXRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  氧化异佛尔酮 在 ammonium hydroxide 作用下， 反应 6.0h， 生成 2-amino-3,5,5-trimethylcyclohex-2-en-1-one
  参考文献：
  名称：

  Dihydroindol-7(6H)-ones and 6,7-Dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione

  摘要：

  3-甲基环己烯酮可以通过环氧化物转化为 2-苄基氨基-3-甲基环己烯酮而转化为二氢吲哚-7(6H)-酮，后者与二甲基甲酰胺二甲基缩醛反应生成 N-苄基二氢吲哚-7(6H)-酮。讨论了该工艺的局限性，以及无法通过贝克曼或施密特重排将二氢吲哚-7(6H)-酮转化为二氢吡咯氮杂环己二酮的问题。后一种化合物的一个例子是通过简单的方法从吡咯羧酸制得的。

  DOI：

  10.1071/ch9900355

文献信息

• ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION
  申请人：ASAHI KASEI CHEMICALS CORPORATION

  公开号：US20160016901A1

  公开（公告）日：2016-01-21

  The present invention relates to an isothiocyanate production method using an organic primary amine and thiourea as starting materials; to a composition for transporting and storing an N-substituted O-substituted thiocarbamate that includes an N-substituted O-substituted thiocarbamate and a hydroxy compound, the equivalent weight ratio of hydroxy groups of the hydroxy compound with respect to the carbamate groups of the N-substituted O-substituted thiocarbamate being in the range of 1 to 100; to a composition for transporting and storing a compound with a thioureido group that includes a compound with a thioureido group and a hydroxy compound, the equivalent weight ratio of hydroxy groups of the hydroxy compound with respect to the thioureido groups of the compound with a thioureido group being in the range of 1 to 100; and to an isothiocyanate composition containing an isothiocyanate and a compound with a specific functional group.

  该发明涉及一种使用有机初级胺和硫脲作为起始原料的异硫氰酸酯生产方法；一种用于运输和储存N-取代O-取代硫代氨基甲酸酯的组合物，包括N-取代O-取代硫代氨基甲酸酯和羟基化合物，羟基化合物的羟基与N-取代O-取代硫代氨基甲酸酯的羰基的当量重量比在1到100的范围内；一种用于运输和储存具有硫脲基团的化合物的组合物，包括具有硫脲基团的化合物和羟基化合物，羟基化合物的羟基与具有硫脲基团的化合物的硫脲基团的当量重量比在1到100的范围内；以及含有异硫氰酸酯和具有特定功能基团的化合物的异硫氰酸酯组合物。
• Medical Adhesive
  申请人：Yoshimura Tetsuji

  公开号：US20070282093A1

  公开（公告）日：2007-12-06

  The present invention has its object to provide a medical adhesive excellent in safety, reactivity (curing rate) and duration of adhesive strength. A medical adhesive of the present invention comprises a hydrophilic urethane prepolymer (UP) obtained by reacting a fluorine-containing nonaromatic polyisocyanate component (A) and a polyol component (B) having a hydrophilic polyol (B 1 ) as the essential component, and a phenolic radical scavenger (PRS). The content of (PRS) is preferably 0.01 to 3% by weight based on the weight of (UP). The content of oxyethylene groups in (B) is preferably 30 to 100% by weight based on the weight of the oxyalkylene groups in (B). Preferably, (B) is a mixture of a random copolymer obtained by addition of ethylene oxide and propylene oxide to diols and polypropylene glycol. The content of isocyanate groups in the medical adhesive is 1 to 10% by weight based on the weight of (UP). The medical adhesive of the present invention is suitable for bonding body tissues, such as lung, artery and heart in particular.

  本发明的目的是提供一种在安全性、反应性（固化速率）和粘接强度持续时间方面具有优异性能的医用粘合剂。本发明的医用粘合剂包括通过反应含氟非芳香族多异氰酸酯组分（A）和具有亲水性多元醇（B1）作为基本组分的多元醇组分（B）获得的亲水性聚氨酯预聚物（UP）和酚类自由基清除剂（PRS）。根据（UP）的重量，（PRS）的含量优选为0.01至3重量％。根据（B）中氧乙烯基团的重量，氧乙烯基团的含量优选为30至100重量％。优选地，（B）是通过将环氧丙烷和丙烯酸酯添加到双醇和聚丙烯醇中获得的随机共聚物的混合物。医用粘合剂中异氰酸酯基团的含量根据（UP）的重量为1至10重量％。本发明的医用粘合剂特别适用于粘接肺、动脉和心脏等体内组织。
• Acrylic polymers containing hydrolyzable moieties from organosilane compounds
  申请人：PPG INDUSTRIES, INC.

  公开号：EP0205827A2

  公开（公告）日：1986-12-30

  Disclosed is an ungelled acrylic resin composition containing an acrylic polymer having in a molecule thereof at least one group containing a silicon atom selected from: . and wherein each R independently is selected from the group of moieties consisting of Y, hydrogen, a C,-C,o group joined to Si through an Si-C linkage, and OR7 in which R7 represents alkyl having at least 4 carbon atoms, aryl, alkylaryl, arylalkyl, aryloxyalkyl, or alkyloxyalkyl, wherein Y represents an easily hydrolyzable group. The acrylic resin composition, contains an amount of easily hydrolyzable Y moieties such that the ratio of the number of grams of the ungelled acrylic resin composition to equivalent of easily hydrolyzable Y moieties in the ungelled acrylic resin composition is in a range of from 40 to 667. Preferred acrylic resin compositions of the invention can be cured in the presence of atmospheric moisture and a suitable catalyst at a temperature of less than or equal to 121 degrees Celsius within 3 hours. Disclosed is a method for producing the ungelled acrylic resin composition. Also disclosed is a nonaqueous composition, particularly a nonaqueous coating composition, containing the ungelled acrylic resin composition. Preferred coating compositions containing an ungelled acrylic resin composition can be cured in the presence of atmospheric moisture and a suitable catalyst at a temperature of less than or equal to 121 degrees C within 3 hours.

  本发明公开了一种未胶凝的丙烯酸树脂组合物，该组合物含有一种丙烯酸聚合物，其分子中至少有一个含有硅原子的基团，该硅原子选自......： 和 其中每个R独立地选自由Y、氢、通过Si-C连接与Si连接的C,-C,o基团和OR7组成的分子组，其中R7代表至少有4个碳原子的烷基、芳基、烷芳基、芳烷基、芳氧基烷基或烷氧基烷基，其中Y代表易水解基团。 丙烯酸树脂组合物含有一定量的易水解 Y 基，使未胶化丙烯酸树脂组合物的克数与未胶化丙烯酸树脂组合物中易水解 Y 基的当量之比范围在 40 至 667 之间。优选的本发明丙烯酸树脂组合物可以在大气湿度和适当催化剂的存在下，在小于或等于 121 摄氏度的温度下于 3 小时内固化。 本发明公开了一种生产未胶化丙烯酸树脂组合物的方法。 还公开了一种含有未胶凝丙烯酸树脂组合物的非水组合物，特别是非水涂料组合物。含有未胶化丙烯酸树脂组合物的优选涂料组合物可在大气湿度和适当催化剂存在下，在小于或等于 121 摄氏度的温度下于 3 小时内固化。
• Prepregs, comprising only one of the reactive components, and composites derived from them
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0939099A2

  公开（公告）日：1999-09-01

  Composite, obtainable by hot pressing or vacuum bagging a multilayer of prepregs of reinforcing webs impregnated with duroplastic resin systems, wherein at least one layer of an epoxy resin prepreg and at least one layer of a prepreg comprising a curing agent and/or an adduct of an epoxy resin and a curing agent, and prepregs to be used therefore. As curing agent preferably a polyamine is used.

  复合材料，可通过热压或真空袋包装浸渍有杜罗塑料树脂体系的多层加固网预浸料来获得，其中至少有一层环氧树脂预浸料和至少有一层包含固化剂和/或环氧树脂与固化剂的加合物的预浸料，以及因此而使用的预浸料。固化剂最好使用多胺。
• MEDICAL ADHESIVE
  申请人：Sanyo Chemical Industries, Ltd.

  公开号：EP1741454A1

  公开（公告）日：2007-01-10

  The present invention has its object to provide a medical adhesive excellent in safety, reactivity (curing rate) and duration of adhesive strength. A medical adhesive of the present invention comprises a hydrophilic urethane prepolymer (UP) obtained by reacting a fluorine-containing nonaromatic polyisocyanate component (A) and a polyol component (B) having a hydrophilic polyol (B1) as the essential component, and a phenolic radical scavenger (PRS). The content of (PRS) is preferably 0.01 to 3% by weight based on the weight of (UP). The content of oxyethylene groups in (B) is preferably 30 to 100% by weight based on the weight of the oxyalkylene groups in (B). Preferably, (B) is a mixture of a random copolymer obtained by addition of ethylene oxide and propylene oxide to diols and polypropylene glycol. The content of isocyanate groups in the medical adhesive is 1 to 10% by weight based on the weight of (UP). The medical adhesive of the present invention is suitable for bonding body tissues, such as lung, artery and heart in particular.

  本发明的目的是提供一种在安全性、反应性（固化率）和粘合强度持续时间方面都非常出色的医用粘合剂。 本发明的一种医用粘合剂由亲水性聚氨酯预聚物（UP）和酚基清除剂（PRS）组成，亲水性聚氨酯预聚物（UP）是由含氟非芳香族多异氰酸酯组分（A）和以亲水性多元醇（B1）为基本组分的多元醇组分（B）反应而得。PRS 的含量最好为（UP）重量的 0.01 至 3%。以（B）中氧烷基的重量为基准，（B）中氧烷基的含量最好为 30%至 100%。优选地，(B) 是无规共聚物的混合物，通过将环氧乙烷和环氧丙烷添加到二元醇和聚丙二醇中获得。医用粘合剂中异氰酸酯基团的含量为 1-10%（以（UP）的重量为基准）。本发明的医用粘合剂特别适用于粘合人体组织，如肺、动脉和心脏。