(4-nitro)phenyl 2,3,5,6-tetra-O-acetyl-α-L-idofuranoside | 848310-21-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4-nitro)phenyl 2,3,5,6-tetra-O-acetyl-α-L-idofuranoside
• CAS: 848310-21-4
• 化学式: C₂₀H₂₃NO₁₂
• 分子量: 469.402
• InChiKey: QXQLXODSWYVHJM-PXTPFGJHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.06
• 重原子数：
  33.0
• 可旋转键数：
  9.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  166.8
• 氢给体数：
  0.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  (4-nitro)phenyl 2,3,5,6-tetra-O-acetyl-α-L-idofuranoside 在 sodium methylate 作用下， 以 甲醇 为溶剂， 以90%的产率得到(4-nitro)phenyl α-L-idofuranoside
  参考文献：
  名称：

  Non-natural aldofuranosides as substrates of a β-glucosidase

  摘要：

  Based on glycosidase inhibitory activities of some known 1,4-iminoalditols, four aldofuranosides, (4-nitro)phenyl beta-D-glucofuranoside, -beta-D-galactofuranoside, -alpha-L-idofuranoside and -alpha-L-altrofuranoside, were identified as possible substrates of glucosidases and galactosidases. Three of them were found to be accepted by the beta-glucosidase from Agrobacterium sp. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.027
• 作为产物：
  描述：

  3,5,6-tri-O-acetyl-1,2-O-isopropylidene-β-L-idofuranose 在 硫酸 、 对甲苯磺酸 、 溶剂黄146 作用下， 以 甲苯 为溶剂， 反应 3.0h， 生成 (4-nitro)phenyl 2,3,5,6-tetra-O-acetyl-α-L-idofuranoside
  参考文献：
  名称：

  Non-natural aldofuranosides as substrates of a β-glucosidase

  摘要：

  Based on glycosidase inhibitory activities of some known 1,4-iminoalditols, four aldofuranosides, (4-nitro)phenyl beta-D-glucofuranoside, -beta-D-galactofuranoside, -alpha-L-idofuranoside and -alpha-L-altrofuranoside, were identified as possible substrates of glucosidases and galactosidases. Three of them were found to be accepted by the beta-glucosidase from Agrobacterium sp. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.11.027