4-methylquinolin-2-yl trifluoromethanesulfonate | 108530-09-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-methylquinolin-2-yl trifluoromethanesulfonate
• 英文别名: (4-methylquinolin-2-yl) trifluoromethanesulfonate
• CAS: 108530-09-2
• 化学式: C₁₁H₈F₃NO₃S
• 分子量: 291.251
• InChiKey: UNLMODLSZOTUGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  4-methylquinolin-2-yl trifluoromethanesulfonate 在 1,1'-双(二苯基膦)二茂铁 、 甲酸 、 palladium diacetate 、 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.0h， 以82%的产率得到4-甲基喹啉
  参考文献：
  名称：

  钯催化的甲酸三乙铵还原芳基三氟甲磺酸酯。苯酚脱氧的选择性方法

  摘要：

  在均相钯催化剂的存在下，通过用甲酸三乙铵还原相应的芳基三氟甲磺酸酯，可以对苯酚进行选择性脱氧。

  DOI：

  10.1016/s0040-4039(00)85262-4
• 作为产物：
  描述：

  三氟甲磺酸酐 、 2-羟基-4-甲基喹啉 在 吡啶 作用下， 反应 24.0h， 以78%的产率得到4-methylquinolin-2-yl trifluoromethanesulfonate
  参考文献：
  名称：

  Microwave-Assisted Trans-Halogenation Reactions of Various Chloro-, Bromo-, Trifluoromethanesulfonyloxy- and Nonafluorobutanesulfonyloxy-Substituted Quinolines, Isoquinolines, and Pyridines Leading to the Corresponding Iodinated Heterocycles

  摘要：

  Microwave irradiation of certain chloro-, bromo-, trifluoromethanesulfonyloxy- and nonafluorobutanesulfonyloxy-substituted quinolines in the presence of acetic. anhydride and sodium iodide leads, via a trans-halogenation process, to the corresponding iodides in high yield. Related conversions involving pyridines and isoquinolines can also be achieved under similar conditions.

  DOI：

  10.1021/jo9008386

文献信息

• Palladium-catalyzed carbonylation of aryl triplates. Synthesis of arenecarboxylic acid derivatives from phenols
  作者：Sandro Cacchi、Pier Giuseppe Ciattini、Enrico Morera、Giorgio Ortar

  DOI：10.1016/s0040-4039(00)83920-9

  日期：1986.1

  Various aryl triflates derived from phenols were converted into aryl esters or amides in good yields by a palladium-catalyzed reaction with carbon monoxide and alcohols or amines.

  通过与一氧化碳和醇或胺的钯催化反应，衍生自苯酚的各种芳基三氟甲磺酸酯以良好的产率转化为芳基酯或酰胺。
• A simple route to 1,4-addition reactions by Co-catalyzed reductive coupling of organic tosylates and triflates with activated alkenes
  作者：Jen-Chieh Hsieh、Yi-Hua Chu、Krishnamoorthy Muralirajan、Chien-Hong Cheng

  DOI：10.1039/c7cc06881f

  日期：——

  An efficient Co-catalyzed 1,4-addition reaction of alkyl/aryl triflates and tosylates with activated alkenes is described. In this reaction, air-stable cobalt(II) complex, mild reducing agent Zn and simple proton source (H2O) are used. A radical mechanism for the addition of alkyl tosylates to activated alkenes is likely involved.

  描述了烷基/芳基三氟甲磺酸酯和甲苯磺酸酯与活化的烯烃的有效的共催化的1,4-加成反应。在该反应中，使用了空气稳定的钴（II）配合物，温和的还原剂Zn和简单的质子源（H2O）。可能存在将烷基甲苯磺酸酯加成到活化烯烃上的自由基机理。
• An efficient preparation of indolizines through a tandem palladium-catalyzed cross-coupling reaction and cycloisomerization
  作者：Hyunseok Kim、Kwangmoo Lee、Sunggak Kim、Phil Ho Lee

  DOI：10.1039/c0cc01945c

  日期：——

  An efficient synthetic method for producing indolizines through a tandem Pd-catalyzed selective allenyl cross-coupling reaction using organoindium reagents and cycloisomerization was developed in a one-pot process.

  一种高效的合成方法通过在一步反应中采用钯催化的选择性烯丙基交叉偶联反应以及环状异构化，使用有机铟试剂合成了吲哚啉。
• NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME
  申请人：Murakami Masahiro

  公开号：US20110046372A1

  公开（公告）日：2011-02-24

  The present invention provides novel boron compounds which are useful, depending on their characteristics, as light-emitting materials, electron-transport materials, electron-injection materials, hole-blocking materials, or organic semiconductor materials, and which have new molecular structures quite different from those of the heretofore known boron compounds; their production processes; and functional electronic devices using the same. The novel boron compounds are, for example, those of the following formula (1): These boron compounds can be produced by, for example, reacting boron compounds of the following formula (4): with compounds of the following formula (5): in the presence of a catalyst containing at least one metal element selected from the group consisting of palladium, platinum, and nickel. These boron compounds are used for the functional electronic devices.

  本发明提供了新型硼化合物，根据其特性，可以作为发光材料、电子传输材料、电子注入材料、阻挡空穴材料或有机半导体材料，并具有与迄今为止已知的硼化合物完全不同的新分子结构；它们的生产过程；以及使用它们的功能电子器件。新型硼化合物例如为以下式子（1）的化合物：这些硼化合物可以通过例如在至少包含铂、钯和镍组成的金属元素中选择至少一种催化剂的存在下，将以下式子（4）的硼化合物与以下式子（5）的化合物反应制备而成。这些硼化合物用于功能电子器件。
• CACCHI S.; CIATTINI P. G.; MORERA E.; ORTAR G., TETRAHEDRON LETT., 27,(1986) N 45, 5541-5544
  作者：CACCHI S.、 CIATTINI P. G.、 MORERA E.、 ORTAR G.

  DOI：——

  日期：——