phenanthridin-3-ol | 99585-74-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: phenanthridin-3-ol
• 英文别名: 3-phenanthridinol；3-Hydroxyphenanthridin；3-Phenanthridinol
• CAS: 99585-74-7
• 化学式: C₁₃H₉NO
• 分子量: 195.221
• InChiKey: PVRBBNVBVWFJSC-UHFFFAOYSA-N

物化性质

• 沸点：
  420.6±18.0 °C(Predicted)
• 密度：
  1.307±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(4-羟基苯基)苯甲醛 在 fac-tris(2-phenylpyridinato-N,C2')iridium(III) 、 4-氯苯磺酸 、 4-(aminooxycarbonyl)benzonitrile 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以67%的产率得到phenanthridin-3-ol
  参考文献：
  名称：

  Visible-Light-Promoted and One-Pot Synthesis of Phenanthridines and Quinolines from Aldehydes and O-Acyl Hydroxylamine

  摘要：

  A one-pot synthesis of phenanthridines and quinolines from commercially available or easily prepared aldehydes has been reported. O-(4-Cyanobenzoyl)hydroxylamine was utilized as the nitrogen source to generate O-acyl oximes in situ with aldehydes catalyzed by Bronsted acid. O-Acyl oximes were then subjected to visible light photoredox catalyzed cyclization via iminyl radicals to furnish aza-arenes. A variety of phenanthridines and quinolines have been prepared assisted by Bronsted acid and photocatalyst under visible light at room temperature with satisfactory yields.

  DOI：

  10.1021/acs.orglett.5b01096

文献信息

• Reactions of organic azides. Part III. The synthesis of phenanthridines by the interaction of fluoren-9-ols with hydrazoic and sulphuric acids, and the mechanism of the rearrangement of the intermediate azides
  作者：C. L. Arcus、M. M. Coombs

  DOI：10.1039/jr9540004319

  日期：——
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427B1

  公开（公告）日：1989-07-05
• METHOD OF AND COMPOSITIONS FOR REDUCING WEAR ON SURFACES SUBJECTED TO FRICTIONAL FORCES
  申请人：NATIONAL RESEARCH DEVELOPMENT CORPORATION

  公开号：EP0420868A1

  公开（公告）日：1991-04-10
• METHOD OF FOR REDUCING WEAR ON SURFACES SUBJECTED TO FRICTIONAL FORCES
  申请人：BRITISH TECHNOLOGY GROUP LIMITED

  公开号：EP0420868B1

  公开（公告）日：1993-09-15
• ANTI-MICROBIAL COMPOSITION COMPRISING A METAL ION CHELATING AGENT
  申请人：AQ+ PLC

  公开号：EP1474101A1

  公开（公告）日：2004-11-10