1,6-anhydro-2-deoxy-4-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranose | 220099-50-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,6-anhydro-2-deoxy-4-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranose
• CAS: 220099-50-3
• 化学式: C₄₀H₄₄O₉
• 分子量: 668.784
• InChiKey: FMMOQIGNHRETCR-JGPMOYKUSA-N

物化性质

• 沸点：
  784.572±60.00 °C(Press: 760.00 Torr)(predicted)
• 密度：
  1.283±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.58
• 重原子数：
  49.0
• 可旋转键数：
  15.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  94.07
• 氢给体数：
  1.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  溴甲苯 、 1,6-anhydro-2-deoxy-4-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranose 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以88.1%的产率得到(1R,2S,3R,5R)-3-phenylmethoxy-2-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxy-6,8-dioxabicyclo[3.2.1]octane
  参考文献：
  名称：

  The chemical synthesis of a cyclic oligosaccharide derivative with branching

  摘要：

  A cyclic oligosaccharide derivative was synthesized by cationic ring-opening polymerization of an anhydrodisaccharide derivative under high vacuum in dichloromethane with 20 mol% of PF5 as initiator. Analysis of the spectral results showed that the oligomer chain is composed of only 3 glucose units connected by alpha-1,6 linkages with a glucopyranosyl branching unit at C-4 of each sugar residue in the main chain. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02234-5
• 作为产物：
  描述：

  1,6:2,3-dianhydro-4-O-(2,3,5,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-mannopyranose 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 4.0h， 以82.6%的产率得到1,6-anhydro-2-deoxy-4-O-(2',3',4',6'-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-glucopyranose
  参考文献：
  名称：

  The chemical synthesis of a cyclic oligosaccharide derivative with branching

  摘要：

  A cyclic oligosaccharide derivative was synthesized by cationic ring-opening polymerization of an anhydrodisaccharide derivative under high vacuum in dichloromethane with 20 mol% of PF5 as initiator. Analysis of the spectral results showed that the oligomer chain is composed of only 3 glucose units connected by alpha-1,6 linkages with a glucopyranosyl branching unit at C-4 of each sugar residue in the main chain. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02234-5