N-(3-(trimethoxysilyl)propyl)quinolin-8-amine hydroiodide | 1430743-52-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(3-(trimethoxysilyl)propyl)quinolin-8-amine hydroiodide
• CAS: 1430743-52-4
• 化学式: C₁₅H₂₂N₂O₃Si*HI
• 分子量: 434.349
• InChiKey: QUGXSVRRZNRKBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.53
• 重原子数：
  22.0
• 可旋转键数：
  8.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  52.61
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  8-氨基喹啉 、 3-碘苯基三甲氧基硅烷 以 四氢呋喃 为溶剂， 反应 72.0h， 以70%的产率得到N-(3-(trimethoxysilyl)propyl)quinolin-8-amine hydroiodide
  参考文献：
  名称：

  Mo(II) complexes of 8-aminoquinoline and their immobilization in MCM-41

  摘要：

  Two new Mo(II) complexes [MoBr(eta(3)-C3H5)(CO)(2)(8-aq)] (1) and [MoI2(CO)(3)(8-aq)] (2) containing the bidentate 8-aminoquinoline ligand (8-aq) were synthesized and characterized. They were immobilized in MCM-41. A 3-iodopropyltrimethoxysilane spacer reacted both with the surface, through the silane, and through the other end, with the coordinated 8-aq of complexes 1 and 2, leading to an immobilized form of the complex (MCM-Pr-1,2). In an alternative route, 8-aq reacted with 3-iodopropyltrimethoxysilane to form a new ligand L-1, which could be supported in the MCM-41 and then react with the metal precursors to afford (MCM-L-1-1,2). The complexes and the materials were characterized using FTIR and NMR spectroscopies, and the structure of the materials was checked with powder X-ray diffraction and nitrogen adsorption isotherms. The first synthetic procedure was less efficient in terms of metal load inside the channels of the materials.The complexes and the new materials were tested as catalytic precursors in the epoxidation of cis-cycloctene, styrene, 1-octene, R-(+)limonene, geraniol, cis-3-hexene-1-ol and trans-2-hexene-1-ol, using tert-butylhydroperoxide (TBHP) as oxidant. Although almost all the catalysts were 100% selective toward the epoxide, the conversions were in general poor. The best catalyst was complex 1, but the conversions dropped after immobilization. Conversions could be a bit improved by a careful choice of reaction conditions, the most effective being the absence of added solvent (the substrate acted as solvent). (c) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.apcata.2013.01.033