(1R,3R,4S)-3-Diphenylphosphanyl-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one | 133099-26-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,3R,4S)-3-Diphenylphosphanyl-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one
• CAS: 133099-26-0
• 化学式: C₂₂H₂₅OP
• 分子量: 336.414
• InChiKey: TWMVZZSFPQEVRP-KNKQGSTJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.51
• 重原子数：
  24.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  (1R,3R,4S)-3-Diphenylphosphanyl-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 在 lithium aluminium tetrahydride 、 双氧水 作用下， 以 四氢呋喃 为溶剂， 生成 (1R)-endo,endo-3S-(diphenylphosphoryl)-2R-hydroxybornane
  参考文献：
  名称：

  Camphor-based β-hydroxyphosphoryl ligands and their complexes of the type [MoO(O₂)₂L(H₂O)]

  摘要：

  Homochiral hydroxyphosphoryl compounds, L, such as-the novel camphor-based(1R)-endo, endo-3S-(diphenylphosphoryl)-2R-hydroxybornane, have been found to be prevented from behaving as bidentate ligands in the epoxidation catalysts [MoO(O-2)(2)L(H2O)] by unexpectedly strong multiple-bond delocalisation producing near linear Mo-O-P angles.

  DOI：

  10.1039/dt9960004149
• 作为产物：
  描述：

  白樟油 、 二苯基氯化膦 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 生成 (1R,3R,4S)-3-Diphenylphosphanyl-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one
  参考文献：
  名称：

  Camphor-based β-hydroxyphosphoryl ligands and their complexes of the type [MoO(O₂)₂L(H₂O)]

  摘要：

  Homochiral hydroxyphosphoryl compounds, L, such as-the novel camphor-based(1R)-endo, endo-3S-(diphenylphosphoryl)-2R-hydroxybornane, have been found to be prevented from behaving as bidentate ligands in the epoxidation catalysts [MoO(O-2)(2)L(H2O)] by unexpectedly strong multiple-bond delocalisation producing near linear Mo-O-P angles.

  DOI：

  10.1039/dt9960004149