beta-Chlorocinnamoyl chloride | 85311-59-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: beta-Chlorocinnamoyl chloride
• 英文别名: 3-chloro-3-phenylprop-2-enoyl chloride
• CAS: 85311-59-7
• 化学式: C₉H₆Cl₂O
• 分子量: 201.052
• InChiKey: LNXLTDIDRGQAEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  beta-Chlorocinnamoyl chloride 在 水 作用下， 生成 (E)-3-chloro-3-phenyl-2-propenoic acid 、 (Z)-3-chloro-3-phenyl-2-propenoic acid
  参考文献：
  名称：

  (E,Z)-3-Chloro-2-propenamides、酸和酯在 DMF 中从 2,3-乙炔酸与草酰氯的简便合成

  摘要：

  摘要描述了通过 2,3-炔酸与草酰氯反应合成 E 和 Z 3-氯-2-丙烯酰胺 (4a-e)、酯 (3a) 和酸 (2a-c) 的简单路线。在 DMF 中，然后用胺、醇和水处理相应的 3-氯-2-丙烯酰氯衍生物。

  DOI：

  10.1081/scc-120027713
• 作为产物：
  描述：

  苯丙炔酸 在 草酰氯 、 N,N-二甲基甲酰胺 作用下， 反应 0.75h， 生成 beta-Chlorocinnamoyl chloride
  参考文献：
  名称：

  (E,Z)-3-Chloro-2-propenamides、酸和酯在 DMF 中从 2,3-乙炔酸与草酰氯的简便合成

  摘要：

  摘要描述了通过 2,3-炔酸与草酰氯反应合成 E 和 Z 3-氯-2-丙烯酰胺 (4a-e)、酯 (3a) 和酸 (2a-c) 的简单路线。在 DMF 中，然后用胺、醇和水处理相应的 3-氯-2-丙烯酰氯衍生物。

  DOI：

  10.1081/scc-120027713

文献信息

• Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain
  申请人：——

  公开号：US04936904A1

  公开（公告）日：1990-06-26

  The present invention relates to N-alkyl-2-aryl-4-oxonicotinates, N-alkyl-5-aryl-4-oxonicotinates, N-alkyl-6-aryl-4-oxonicotinates and N-alkyl-2,6-diaryl-4-oxonicotinates and their use as plant hybridization agents especially useful in wheat, barley and corn. These compounds are particularly active as chemical gametocides and possess a high degree of male/female selectivity. Moreover, these compounds are relatively noninjurious to both corn and wheat crops. The fact that these chemicals possess a high degree of male sterility without affecting female fertility makes them very useful as chemical gametocides.

  本发明涉及N-烷基-2-芳基-4-羟基吡啶酮酸酯、N-烷基-5-芳基-4-羟基吡啶酮酸酯、N-烷基-6-芳基-4-羟基吡啶酮酸酯和N-烷基-2,6-二芳基-4-羟基吡啶酮酸酯及其作为植物杂交剂的用途，特别适用于小麦、大麦和玉米。这些化合物在化学杂交中具有特别的活性，并具有很高的雄性/雌性选择性。此外，这些化合物对玉米和小麦作物相对无害。这些化学物质具有很高的雄性不育性而不影响雌性育性，使它们非常有用作为化学杂交剂。
• Certain-2,6-diphenyl-1,4-dihydro-4-oxo-nicotinates which are useful for
  申请人：Monsanto Company

  公开号：US04964896A1

  公开（公告）日：1990-10-23

  This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 is an optionally substituted alkyl or alkenyl group; at least one of R.sub.2, R.sub.5 and R.sub.6 is ##STR2## wherein (1) when R.sub.2 is ##STR3## R.sub.5 is a hydrogen atom, an alkyl group or a halogen atom and R.sub.6 is a hydrogen atom or an alkyl group, (2) when R.sub.5 is ##STR4## R.sub.2 is an alkyl group and R.sub.6 is a hydrogen atom or an alkyl group, (3) when R.sub.6 is ##STR5## R.sub.2 is an optionally substituted (C.sub.1 -C.sub.6) alkyl or a (C.sub.3 -C.sub.6) alkenyl group and R.sub.5 is a hydrogen atom, a (C.sub.1 -C.sub.6) alkyl group or a halogen atom, and (4) when R.sub.2 and R.sub.6 are both independently ##STR6## R.sub.5 is hydrogen atom or an alkyl group; Y is a hydrogen atom or an alkyl group; X is a hydrogen atom, a halogen atom, a trihalomethyl group and the like; and n is an integer from 1 to 3; or the agronomically acceptable alkali metal or acid addition salts thereof. These compounds are useful as chemical hybridization agents on monocotyledonous crops and are especially effective in wheat, corn, barley, rice, rye, triticale and forage crops.

  本发明涉及以下式的化合物：## STR1 ## 其中R.sub.1是可选取代的烷基或烯基基团；R.sub.2，R.sub.5和R.sub.6中至少有一个是##STR2## 其中（1）当R.sub.2为##STR3## R.sub.5是氢原子，烷基或卤素原子，R.sub.6是氢原子或烷基基团， （2）当R.sub.5为##STR4## R.sub.2是烷基，R.sub.6是氢原子或烷基基团， （3）当R.sub.6为##STR5## R.sub.2是可选取代的（C.sub.1-C.sub.6）烷基或（C.sub.3-C.sub.6）烯基基团，R.sub.5是氢原子，（C.sub.1-C.sub.6）烷基或卤素原子， （4）当R.sub.2和R.sub.6都独立为##STR6## R.sub.5是氢原子或烷基基团；Y是氢原子或烷基基团；X是氢原子，卤素原子，三卤甲基基团等；n是1到3的整数；或其对农业有益的碱金属或酸加合盐。这些化合物在单子叶作物的化学杂交剂中很有用，特别是在小麦、玉米、大麦、稻米、黑麦、小黑麦和饲料作物中特别有效。
• Certain 2-phenyl-4-oxo-nicotinates and their use for inducing male
  申请人：Rohm and Haas Company

  公开号：US04714492A1

  公开（公告）日：1987-12-22

  This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 is an optionally substituted alkyl or alkenyl group; at least one of R.sub.2, R.sub.5 and R.sub.6 is ##STR2## wherein (1) when R.sub.2 is ##STR3## R.sub.5 is a hydrogen atom, an alkyl group or a halogen atom and R.sub.6 is a hydrogen atom or an alkyl group, (2) when R.sub.5 is ##STR4## R.sub.2 is an alkyl group and R.sub.6 is a hydrogen atom or an alkyl group, (3) when R.sub.6 is ##STR5## R.sub.2 is an optionally substituted (C.sub.1 -C.sub.6) alkyl or a (C.sub.3 -C.sub.6) alkenyl group and R.sub.5 is a hydrogen atom, a (C.sub.1 -C.sub.6) alkyl group or a halogen atom, and (4) when R.sub.2 and R.sub.6 are both independently ##STR6## R.sub.5 is a hydrogen atom or an alkyl group; Y is a hydrogen atom or an alkyl group; X is a hydrogen atom, a halogen atom, a trihalomethyl group and the like; and n is an integer from 1 to 3; or the agronomically acceptable alkali metal or acid addition salts thereof. These compounds are useful as chemical hybridization agents on moncotyledonous crops and are especially effective in wheat, corn, barley, rice, rye, triticale and forage crops.

  本发明涉及以下式的化合物：## STR1 ## 其中R1是可选取代的烷基或烯基基团；R2、R5和R6中至少一个为## STR2 ## 其中（1）当R2为## STR3 ##时，R5为氢原子、烷基或卤素原子，R6为氢原子或烷基；（2）当R5为## STR4 ##时，R2为烷基，R6为氢原子或烷基；（3）当R6为## STR5 ##时，R2为可选取代的（C1-C6）烷基或（C3-C6）烯基基团，R5为氢原子、（C1-C6）烷基或卤素原子；（4）当R2和R6均独立为## STR6 ##时，R5为氢原子或烷基；Y为氢原子或烷基；X为氢原子、卤素原子、三卤甲基基团等；n为1至3的整数；或其农业上可接受的碱金属或酸加成盐。这些化合物可用作单子叶作物的化学杂交剂，尤其在小麦、玉米、大麦、水稻、黑麦、小黑麦和饲草作物中特别有效。
• INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE
  申请人：Hurley Timothy Brian

  公开号：US20090203694A1

  公开（公告）日：2009-08-13

  The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection.

  本发明涉及一种选择性和/或强效抑制UPPS的化合物。除了抑制UPPS的化合物外，本发明还提供包含这些化合物的药物组合物以及使用这些化合物治疗细菌性疾病（如细菌感染）的方法。
• US4714492A
  申请人：——

  公开号：US4714492A

  公开（公告）日：1987-12-22