| 945548-23-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 945548-23-2
• 化学式: C₁₃H₁₉N₃O₈
• 分子量: 345.309
• InChiKey: HUMLQACQBBRRKH-XQHKEYJVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.46
• 重原子数：
  24.0
• 可旋转键数：
  7.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  146.12
• 氢给体数：
  0.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  在 palladium on activated charcoal N-乙基吗啉 、 氢气 、 sodium methylate 、 (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 、 1-羟基苯并三唑 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 14.25h， 生成 N-[3-[2-[2-[3-[(4-hydrazinyl-4-oxobutanoyl)amino]propoxy]ethoxy]ethoxy]propyl]-N'-[2-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyethyl]butanediamide
  参考文献：
  名称：

  Carbohydrate Microarrays for Assaying Galactosyltransferase Activity

  摘要：

  Carbohydrate microarrays have been used recently for the rapid analysis of glycan-protein or glycan-cell interactions and for the detection of pathogens. As a demonstration of its significance and versatility, the microarray technology has been applied in this effort to assay glycosyltransferase activities. In addition, carbohydrate microarray based methods have been employed to quantitatively determine binding affinities between lectins and carbohydrates.

  DOI：

  10.1021/ol070250l
• 作为产物：
  描述：

  [(3R,4S,5R,6R)-4,5-diacetoxy-6-(2-bromoethoxy)tetrahydropyran-3-yl] acetate 在 sodium azide 、 四丁基碘化铵 作用下， 以 二甲基亚砜 为溶剂， 生成
  参考文献：
  名称：

  Carbohydrate Microarrays for Assaying Galactosyltransferase Activity

  摘要：

  Carbohydrate microarrays have been used recently for the rapid analysis of glycan-protein or glycan-cell interactions and for the detection of pathogens. As a demonstration of its significance and versatility, the microarray technology has been applied in this effort to assay glycosyltransferase activities. In addition, carbohydrate microarray based methods have been employed to quantitatively determine binding affinities between lectins and carbohydrates.

  DOI：

  10.1021/ol070250l

文献信息

• Fullerene derivative and composition comprising the same
  申请人：——

  公开号：US20040067892A1

  公开（公告）日：2004-04-08

  A fullerene derivative represented by the formula (I): 1 [wherein, A is a residue of monosaccharides or disaccharides, and Alk is a lower alkylene group, the group represented by the formula (X): 2 is a fullerene residual skeleton, and n is an integral number of 1 or 2] or its salt produces a formulation usable for PDT which has more hydrophilicity and lipophilicity, is expected to have selectivity to tumor cells by cell recognition, shows no toxicity to the cells in a dark place and has a cytocidal effect by light irradiation.

  公式(I)代表的富勒烯衍生物：其中，A是单糖或双糖的残基，Alk是较低的烷基烯基团，所表示的团(X)是富勒烯残基骨架，n是1或2的整数，或其盐制剂可用于光动力疗法，具有更多的亲水性和亲脂性，预期通过细胞识别对肿瘤细胞具有选择性，在黑暗条件下对细胞没有毒性，并且通过光照射具有细胞杀伤作用。
• US6844429B2
  申请人：——

  公开号：US6844429B2

  公开（公告）日：2005-01-18