4-Methoxyglucobrassicin | 83327-21-3

• 物质功能分类: 分析化学 - 标准品 - 药典标准品和杂质标准品
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Methoxyglucobrassicin
• 英文别名: [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1Z)-2-(4-methoxy-1H-indol-3-yl)-N-sulfooxyethanimidothioate
• CAS: 83327-21-3
• 化学式: C₁₇H₂₂N₂O₁₀S₂
• 分子量: 478.5
• InChiKey: IIAGSABLXRZUSE-KYKLFQSUSA-N

物化性质

• 密度：
  1.77±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  225
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• P450 Monooxygenases of the cyp79 family
  申请人：——

  公开号：US20030166202A1

  公开（公告）日：2003-09-04

  The invention provides DNA coding for cytochrome P450 monooxygenases of the CYP79 family catalyzing the conversion of an aliphatic or aromatic amino acid or chain-elongated methionine homologue to the corresponding oxime. Preferred embodiments of the invention are enzymes catalyzing the conversion of L-Valine and L-Isoleucine such as the cassava enzymes CYP79D1 and CYP79D2, enzymes catalyzing the conversion of tyrosine such as the Triglochin maritima enzymes CYP79E1 and CYP79E2, enzymes catalyzing the conversion of tryptophan to the corresponding oxime indole-3-acetaldoxime such as the Arabidopsis thaliana enzyme CYP79A2 and the Brassica napus enzyme CYP79B5, and enzymes catalyzing the conversion of a chain-elongated methionine homologue such as the Arabidopsis thaliana enzymes CYP79F1 and CYP79F2. Transgenic expression of said DNA or parts thereof in plants can be used to manipulate the biosynthesis of corresponding glucosinolates or cyanogenic glucosides.

  该发明提供了编码CYP79家族细胞色素P450单加氧酶的DNA，其催化将脂肪族或芳香族氨基酸或链延长的蛋氨酸同源物转化为相应的肟类。该发明的优选实施例是催化L-缬氨酸和L-异亮氨酸转化的酶，例如木薯酶CYP79D1和CYP79D2，催化酪氨酸转化的Triglochin maritima酶CYP79E1和CYP79E2，催化色氨酸转化为相应的肟类吲哚-3-乙醛肟的Arabidopsis thaliana酶CYP79A2和Brassica napus酶CYP79B5，以及催化链延长的蛋氨酸同源物转化的Arabidopsis thaliana酶CYP79F1和CYP79F2。在植物中转基因表达该DNA或其部分可以用于操纵相应的硫代葡萄糖苷或氰基葡萄糖苷的生物合成。
• PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES
  申请人：Bednarek Pawel

  公开号：US20090028796A1

  公开（公告）日：2009-01-29

  The present invention is directed to pesticidal compositions comprising indole derivatives. These indole derivatives are especially active against phytopathogenic fungi. Furthermore, the invention relates to the use of indole derivatives for the production of pesticides and the use of the compositions according to the invention as pesticides. The present invention is also directed to a process for producing a pesticidal composition and to pesticidal compositions prepared by this process. In addition, the invention relates to a process for preventing or combating pests and to a process for protecting plants against pests, especially against phytopathogenic fungi. Further, the invention is directed to plants or seeds as well as objects or materials which have been protected against pests by treatment with a composition according to the invention. Further, the invention is directed to a method for identifying a substance having pesticidal activity. Further, the invention is directed to a method of identifying the mode of action of and/or of providing binding proteins for a pesticidal compound of the present invention. Finally, the invention is directed to a method for diagnosing pest infection of a plant and to the use of a pesticidal compound of the present invention as diagnostic markers.

  本发明涉及包含吲哚衍生物的杀虫组合物。这些吲哚衍生物特别对植物病原真菌具有活性。此外，本发明涉及使用吲哚衍生物制备杀虫剂以及使用本发明中的组合物作为杀虫剂。本发明还涉及制备杀虫组合物的过程以及通过该过程制备的杀虫组合物。此外，本发明还涉及预防或对抗害虫的过程以及保护植物免受害虫，特别是植物病原真菌的过程。此外，本发明还涉及经过本发明中的组合物处理后受到保护的植物或种子以及物体或材料。本发明还涉及识别具有杀虫活性的物质的方法。此外，本发明还涉及识别本发明中杀虫化合物的作用方式和/或提供结合蛋白的方法。最后，本发明涉及诊断植物害虫感染的方法以及使用本发明中的杀虫化合物作为诊断标记的方法。
• Use of compounds that are able to increase the serum IGF-1 level for the preparation of a therapeutical composition for treatment of various disease states associated with a reduced IGF-1 serum level in humans and animals
  申请人：VEIJLEN N.V.

  公开号：US10716778B2

  公开（公告）日：2020-07-21

  The present disclosure relates to the use of one or more compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition, in particular, in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome. The same composition can also be used by patients suffering from depression, Alzheimer disease, irritated bowel syndrome, osteoporosis, type 2 diabetes, or for anti-aging, immune therapy and recovery after exercise. The composition also has a use in veterinary applications for increasing the growth and immunity in animals.

  本公开涉及一种或多种能够提高血清中胰岛素样生长因子1（IGF-1）水平的化合物用于制备治疗组合物，特别是以食品补充剂的形式，用于治疗患有严重疲劳和疲惫症状、倦怠和慢性疲劳综合征的患者。同样的组合物还可用于抑郁症、老年痴呆症、肠易激综合征、骨质疏松症、2 型糖尿病患者，或用于抗衰老、免疫疗法和运动后恢复。该成分还可用于兽医领域，提高动物的生长速度和免疫力。
• P450 MONOOXYGENASES OF THE CYP79 FAMILY
  申请人：Syngenta Participations AG

  公开号：EP1246906A2

  公开（公告）日：2002-10-09
• ANIMAL FEED COMPOSITION
  申请人：Veijlen N.V.

  公开号：EP1667678A1

  公开（公告）日：2006-06-14