2-azidoethyl α-D-xylopyranoside | 937400-93-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-azidoethyl α-D-xylopyranoside
• CAS: 937400-93-6
• 化学式: C₇H₁₃N₃O₅
• 分子量: 219.197
• InChiKey: QNXLFMLUXNXCPJ-UCROKIRRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.25
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  127.91
• 氢给体数：
  3.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  2-azidoethyl α-D-xylopyranoside 在 palladium on activated charcoal N-乙基吗啉 、 氢气 、 (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 、 1-羟基苯并三唑 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 13.25h， 生成 N-[3-[2-[2-[3-[(4-hydrazinyl-4-oxobutanoyl)amino]propoxy]ethoxy]ethoxy]propyl]-N'-[2-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyethyl]butanediamide
  参考文献：
  名称：

  Carbohydrate Microarrays for Assaying Galactosyltransferase Activity

  摘要：

  Carbohydrate microarrays have been used recently for the rapid analysis of glycan-protein or glycan-cell interactions and for the detection of pathogens. As a demonstration of its significance and versatility, the microarray technology has been applied in this effort to assay glycosyltransferase activities. In addition, carbohydrate microarray based methods have been employed to quantitatively determine binding affinities between lectins and carbohydrates.

  DOI：

  10.1021/ol070250l
• 作为产物：
  描述：

  [(3R,4S,5R,6R)-4,5-diacetoxy-6-(2-bromoethoxy)tetrahydropyran-3-yl] acetate 在 sodium azide 、 sodium methylate 、 四丁基碘化铵 作用下， 以 甲醇 、 二甲基亚砜 为溶剂， 反应 1.0h， 生成 2-azidoethyl α-D-xylopyranoside
  参考文献：
  名称：

  Carbohydrate Microarrays for Assaying Galactosyltransferase Activity

  摘要：

  Carbohydrate microarrays have been used recently for the rapid analysis of glycan-protein or glycan-cell interactions and for the detection of pathogens. As a demonstration of its significance and versatility, the microarray technology has been applied in this effort to assay glycosyltransferase activities. In addition, carbohydrate microarray based methods have been employed to quantitatively determine binding affinities between lectins and carbohydrates.

  DOI：

  10.1021/ol070250l