2,3-lutidine hydrochloride | 36316-67-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,3-lutidine hydrochloride
• 英文别名: Lutidinium chloride；dimethylpyridine hydrochloride；1,2-dimethylpyridinium chloride；2,3-dimethylpyridinium chloride；2,3-dimethyl-pyridine; hydrochloride；2,3-Dimethyl-pyridin; Hydrochlorid；lutidine hydrochloride；dimethyl pyridine HCl；2,3-dimethylpyridine;hydrochloride
• CAS: 36316-67-3
• 化学式: C₇H₁₀N*Cl
• 分子量: 143.616
• InChiKey: PKRHOIOVOBITKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.12
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  12.9
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  copper(ll) bromide 、 2,3-lutidine hydrochloride 以 氢溴酸 为溶剂， 生成 (1,2-dimethylpyridinium)2Cu3Br8
  参考文献：
  名称：

  Magnetic properties of two new low-dimensional copper-halide systems

  摘要：

  Powder magnetic susceptibility measurements on two new, low-dimensional copper-halide systems are reported: (piperazinium)2CuCl6.CH3OH, and (1,2-dimethylpyridinium)2Cu3Br8. The data are analyzed using the high- and low-temperature series expansions for a 1D, S = 1/2, Heisenberg Hamiltonian, with a mean-field correction to model the interaction between chains. The piperazinium system shows very weak antiferromagnetism with a possibility of two-dimensional behavior. The pyridinium trimer system shows more strongly ferromagnetically coupled doublet ground states between trimers, which comprise the chain.

  DOI：

  10.1016/0304-8853(92)90381-w
• 作为试剂：
  描述：

  1-十一炔 在 叔丁基过氧化氢 、 锰 、 sodium tetrahydroborate 、 正丁基锂 、 bis(acetylacetonate)oxovanadium 、 C₃₀H₄₆Cl₂Ti 、 氢气 、 三正丁基氢锡 、 nickel(II) acetate tetrahydrate 、 2,3-lutidine hydrochloride 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 为溶剂， 反应 93.5h， 生成 (2R,5S)-tetradecane-2,4-diol 、 Tetradecane-2,5-diol
  参考文献：
  名称：

  通过区域发散性环氧的开放，高选择性地合成1,3和1,4-双功能化的结构单元

  摘要：

  我们描述了一种区域发散性环氧化物开口（REO），其特征在于由催化剂控制的对映体和非对映体高度富集的合成，或由常见的环氧前体合成的纯的顺式和反式1,3和1,4-双官能化的结构单元。REO对于天然产物合成以及作为环氧化物面向多样性的合成的支化反应具有吸引力。

  DOI：

  10.1002/anie.201606064

文献信息

• [CuCl₃(H₂O)]⁻complexes aggregated to form hydrate columns in methyl-substituted pyridinium or piperidinium salts
  作者：Sowjanya Nalla、Marcus R. Bond

  DOI：10.1107/s0108270111017306

  日期：2011.6.15

  1,2,3-Trimethylpyridinium aquatrichloridocuprate(II), (C8H12N)[CuCl3(H2O)], (I), 3,4-dimethylpyridinium aquatrichloridocuprate(II), (C7H10N)[CuCl3(H2O)], (II), and 2,3-dimethylpyridinium aquatrichloridocuprate(II), (C7H10N)[CuCl3(H2O)], (III), exhibit the same fundamental structure, with (I) and (II) isomorphous and with the unit-cell constants of (III) similar to the reduced unit-cell constants of (I) and (II). The distorted square-planar [CuCl3(H2O)](-) complex [mirror symmetric in (I) and (II)] forms two semicoordinate Cu center dot center dot center dot Cl bonds to a neighboring complex to produce a dimer with 2/m symmetry [only inversion symmetry in (III)]. The semicoordinate Cu center dot center dot center dot Cl bond length of the dimer shows significant elongation at 295 K compared with that at 100 K, while the coordinate Cu-Cl bond lengths are slightly contracted at 295 K compared with those at 100 K. The inorganic dimers are linked by eight hydrogen bonds to four neighboring dimers to establish a checkerboard network layer in the ab plane, with voids between the dimers that accommodate, on both sides, inversion-related organic cation pairs. The organic cations are required by mirror-plane symmetry to be disordered in (I) and (II). The organic cations and [CuCl3(H2O)](-) complexes are nearly coplanar and tilted out of the layer plane to establish a hybrid organic-inorganic layer structure parallel to (202) [(11 (2) over bar) in (III)], with hydrate columns (defined by water molecules) and hydrophobic columns (defined by methyl groups) parallel to each other [and along the 2(1) axes in (I) and (II)]. In 1,1-dimethylpiperidinium aquatrichloridocuprate(II), (C7H16N)[CuCl3(H2O)], (IV), the bulkier organic cation prevents semicoordinate bonding between complexes, which are hydrogen bonded side-to-side in zigzag chains that place water molecules in columns along half of the 2(1) axes.
• Structures and Magnetic Susceptibility Studies of Four New High-Nuclearity Copper(II) Halide Oligomers
  作者：M. R. Bond、H. Place、Z. Wang、R. D. Willett、Ying Liu、Todd E. Grigereit、John E. Drumheller、George F. Tuthill

  DOI：10.1021/ic00116a003

  日期：1995.6

  The syntheses, crystal structures, and powder magnetic studies of several new quasi-planar bibridged Cu(n)X(2n+2)(2-) oligomers (n = 3, 4, 6, and 7; X = Cl or Br) are reported, based on the 1-methylpyridinium (C6H8N)(+) and 1,2-dimethylpyridinium (C7H10N)(+) cations. These include (C7H10N)(2)Cu3Br8, (C6H8N)(2)Cu4Cl10, (C7H10N)(2)Cu6Cl14, and (C7H10N)(2)Cu7Br16. Crystallographic data: (C7H10N)(2)Cu3Br8, triclinic, space group P (1) over bar, a = 7.947(2) Angstrom, b = 8.799(2) Angstrom, c = 9.840(2) Angstrom, alpha = 86.95(2)degrees, beta = 76.23(2)degrees, gamma = 71.54(2)degrees, V = 633.6(3) Angstrom(3), Z = 2, d(x) = 2.78 g/cm(3), and R = 0.0483; (C6H8N)(2)Cu4Cl10, monoclinic, space group P2(1)/n, a = 11.759(2) Angstrom, b = 9.056(2) Angstrom, c = 12.048(3) Angstrom, beta = 106.21(2)degrees, V = 1232.1(5) Angstrom(3), Z = 2, d(x) = 2.15 g/cm(3), and R = 0.0321; (C7H10N)(2)Cu6Cl14, triclinic, P (1) over bar, a = 8.997(3) Angstrom, b = 9.288(3) Angstrom, c = 11.540(4) Angstrom, alpha = 80.53(2)degrees, beta = 67.82(2)degrees, gamma = 60.22(2)degrees, V = 714.7(4) Angstrom(3), Z = 1, d(x) = 2.34 g/cm(3), and R = 0.0363; (C6H8N)(2)Cu7Br16, triclinic, P (1) over bar, a = 7.237(2) Angstrom, b = 10.880(2) Angstrom, c = 12.880(2) Angstrom, alpha = 89.47(2) Angstrom, beta = 75.08(2)degrees, gamma = 79.48(2)degrees, V = 962.7(3) Angstrom(3), Z = 1, d(x) = 3.35 g/cm(3), and R = 0.0520. A common feature of the structures is the existence of oligomers containing quasi-planar symmetric bibridged finite chains of edge-sharing CuX(4), (X = halide) monomeric units. The n = 3 oligomers aggregate into chains through the formation of asymmetric bibridged linkages between terminal copper ions on adjacent trimers. In the n = 4 salt, the oligomers aggregate into stacks in which pairs of the copper ions extend their coordination sphere by forming a long, semicoordinate bond to a halide ion from a neighboring oligomer. For both the n = 3 and n = 4 salts, the pyridinium cations lie parallel to and directly above and below the anionic oligomers, separating the chains. In the n = 6 rind n = 7 salts, the stacks formed in this manner interdigitate, forming two-dimensional slabs. The slabs are separated by the organic cations. The magnetic properties of compounds are dominated by antiferromagnetic intraoligomer interactions. Thus, the n = 4 and n = 6 salts depopulate into singlet ground states at low temperature. In contrast, the n = 3 and n = 7 oligomers have S = 1/2 ground states. Expressions for the magnetic susceptibility of the n = 6 and n = 7 oligomers were obtained by diagonalization of a nearest neighbor Heisenberg Hamiltonian. The data were fit to these expressions, with inclusion of a mean field correction for interoligomer exchange. The intra-oligomer exchange coupling constants are J(1)/k = -153 K for n = 3; J(1)/k = -60 K, J(2)/k = -40 K for n = 3; J(1)/k = -23 K, J(2)/k = -30 K, and J(3)/k = -52 K for n = 5 and J(1)/k = -90 K, J(2)/k = -90 K and J(3)/k = -120 K.At low temperature, the n = 3 oligomer exhibits ferromagnetic behavior. Since the oligomer has depopulated to a spin 1/2 ground state, the system can be modeled as a spin 1/2 ferromagnetic chain with J'/k = 22.8 K.
• EP0859768A4
  申请人：——

  公开号：EP0859768A4

  公开（公告）日：1998-11-11
• AMINE ACID SALT COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF
  申请人：Yoo, Seo Hong

  公开号：EP0859768B1

  公开（公告）日：2003-01-08
• NOVEL LACTAM METALLOPROTEASE INHIBITORS
  申请人：Du Pont Pharmaceuticals Company

  公开号：EP1027332A1

  公开（公告）日：2000-08-16