（R）-N'-亚硝基尼古丁 | 61601-78-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: （R）-N'-亚硝基尼古丁
• 英文名称: (R)-N′-nitrosonornicotine
• 英文别名: 3-[(2R)-1-nitrosopyrrolidin-2-yl]pyridine
• CAS: 61601-78-3
• 化学式: C₉H₁₁N₃O
• 分子量: 177.206
• InChiKey: XKABJYQDMJTNGQ-SECBINFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• METHODS AND APPARATUS FOR THE ION MOBILITY BASED SEPARATION AND COLLECTION OF MOLECULES
  申请人：Wu Ching

  公开号：US20080173809A1

  公开（公告）日：2008-07-24

  This invention describes an apparatus for the separation and collection of components in a sample of interest comprising: an ionization source; an ion mobility separator and an ion collector positioned to receive ions leaving the ion mobility separator. The ion mobility separator having an inlet to supply at least one separating substance which comprises particles which selectively interact with at least one analyte component of interest to certain degree different from the others. The analyte component of interest may be enantiomers, diastereomers, stereoisomers, isomers, etc. The ion collector can be used to conduct analytical, preparative, and semi-preparative separation. In addition, a combined primary electrospray and secondary electrospray ionization source is disclosed to enhance ionization efficiency of interest.
• Polymers Selective for Tobacco Specific Nitrosamines and Methods of Using the Same
  申请人：Karlsson Ola John Ivar

  公开号：US20130139835A1

  公开（公告）日：2013-06-06

  A class of molecularly imprinted polymers that specifically recognizes and binds to TSNAs are useful, for example, in analysis and separation of TSNAs from biological fluids. Such polymers are also useful in methods of treating and manufacturing tobacco products and materials. Also disclosed are selectively adsorbent non-molecularly imprinted polymer of a non-acidic monomer and a cross-linker having polar functionality, one of which is hydrophilic, the other of which is hydrophobic, and the use of such polymers in the treatment of materials containing nicotine and nitrosamine.
• Polymers Selective for Nitro-Containing Compounds and Methods of Using the Same
  申请人：British American Tobacco (Investments) Limited

  公开号：US20130139834A1

  公开（公告）日：2013-06-06

  Porous beads are provided of a polymer of a non-acidic monomer and a cross-linker having polar functionality, one of which is hydrophilic, the other of which is hydrophobic, further comprising residues of polyvinyl alcohol. The beads may be molecularly imprinted or non-molecularly imprinted. The use of such beads in the removal of nitroso-containing compounds from material containing them is also disclosed. Also disclosed is a non-molecularly imprinted polymer which is selectively adsorbent for at least one tobacco specific nitrosamine in the presence of nicotine, said polymer being a polymerization product of a non-acidic monomer and a cross-linker having polar functionality, one of which is hydrophilic, the other of which is hydrophobic.
• Improvements in methods of treating tobacco
  申请人：British American Tobacco (Investments) Limited

  公开号：US20180070627A1

  公开（公告）日：2018-03-15

  The invention relates to method of treating a material containing nicotine and at least one nitrosamine to reduce the quantity of nitrosamine therein and to methods of producing a tobacco extract with reduced nitrosamine content. The methods comprise contacting tobacco with a solvent to produce a liquid phase tobacco extract containing nitrosamines and treating the liquid phase tobacco extract to decompose the nitrosamines in the liquid phase. The liquid phase extract may then be treated to reduce nitrosamine decomposition products therein. The invention also relates to tobacco material produced using these methods and to tobacco products incorporating such tobacco material.
• US9243096B2
  申请人：——

  公开号：US9243096B2

  公开（公告）日：2016-01-26